Need to Remember Flashcards
What amino acids absorb UV?
Phe
Tyr
Trp
SAME AS Chymotrypsin
Monoubiquitination regulates …
histones
Multiubiquitination regulates …
endocytosis
What are the 2 endopeptidases?
- trypsin
- chymotrypsin
What amino acid doesn’t have a chiral carbon?
glycine
What is the structure of collagen?
triple helix
Does collagen have left or right handed helix?
left (forms a right supercoil)
What is the structure of keratin?
2 antiparallel dimers form a tetramer
Does Keratin have a right handed or left handed helix?
right (forms a left supercoil)
Jelly rolls beta strands follow the ______ of the barrel
surface
What amino acids have hydroxyl groups?
Ser
Thr
Tyr
PHOSPHORYLATION
What amino acids have amine groups?
Arg
His
Lys
BASIC AMINO ACIDS
What amino acid has thiol groups?
Cys
What amino acids have carboxylate groups?
Aspartic acid
Glutamic acid
Why do tertiary structures have stability?
surface/volume ratio increases favorable protein-protein interactions rate
Why do tertiary structures have efficiency?
large proteins are synthesized in smaller chunks
Why do tertiary structures have assembly?
catalytic sites are made
Why do tertiary structures have regulation?
protein protein interactions
What are the 4 proteases that target functional groups?
Cysteine protease
Serine protease
Aspartic acid protease
Zinc metalloprotease
Where is a left handed helix located on a Ramachndran map?
+60 +60 (top right)
Where is the alpha carbon located?
connected to the NH and carbon with COO on it
T/F? Due to its partial double bond characteristic, the peptide bond does not freely rotate.
true
Are proteins more or less soluble at the isoelectic point?
less
What aid in platelet formation?
fibrin
