Neonatal Sepsis

Question 0

Neonatal sepsis presents how

Answer 0

Anything
GEN-lethargy ,irritable ,temp instability
RS-distress
CVS-bradycardia
GIT-poor feeding,vomiting,and distention ,jaundice
CNS-seizure ,tense fontanell,opisthotonos

Question 1

Neonatal sepsis catogories

Answer 1

Early onset before 72 h

Late onset after 72h -3 months

Question 2

Early onset sepsis risk factors4

Answer 2

PROM
Chorioamnionitis
Maternal fever-UTI
Preterm

Question 3

Organisms come from where in early onset

Answer 3

Fecal o vaginal origin>membranes>amniotic fld>res tract of fetus>sepsis>meningitis

Question 4

Ix in neonatal sepsis 5

Answer 4

FBC 
Blood cultures
CRP
Xray
If meningitis suspect CSF

Question 5

CRP rices when and how does it help

In diagnosis

Answer 5

Rises 12-24 hours later
One value normal can’t exclude sepsis
It 2normal sepsis unlikely

Question 6

Organisms in early sepsis

Answer 6

Gram pos- group B streptococci
Listeria monocytogen
Gram neg-ecoli and others

Question 7

Treatment in early sepsis given when what
When to stop
When to check CSF

Answer 7

Broad spectrum AB wo waiting for reports Genta and c pen
If cultures neg CRP normal omit in 48hrs
If culture positive O any CNS signs

Question 8

Late onset sepsis sources 2

Answer 8

Usually from environment
Also
From birth canal

Question 9

Organisms in late sepsis 5

Answer 9

Common -Staph epididimis
Staph aureus
Pseudomonas
Candida

Less common-group B strepto
Listeriap

Question 10

Treatment in late sepsis

Initially to cover what if not responding

Answer 10

Staph and gram negatives -flucloxacc and Genta

Not resp-Vancomycin

Question 11

If meningitis suspected antibiotics

Answer 11

Penicillin and 3rd gen cephalosporin;cefotaxim)

Question 12

Complications of meningitis early and late

Answer 12

Early -ventriculitis,abscess,hydrocephalus

Late-SN deafness ,cp

Question 13

Grp B streptocc sources 2

Answer 13

Vaginal

Feacal

Question 14

How is GBS transmitted to baby

Answer 14

At delivery

Ascending infection

Question 15

When will GBS sympt present 2

Answer 15

Early

Late 3days to 3 weeks

Question 16

GBS early and late presents how

Answer 16

Pneumonia
Sepsis
Meningitis -rare

Late meningitis
osteomyelitis
Septic arthritis

Question 17

How can it be prevented

Answer 17

By selective and universal screening of mothers and antibiotic prophylaxis at delivery if positive

Question 18

How is Listeria infection transmitted to mother

Answer 18

By consumption of food (unpasteurized milk,under cooked poultry )

Question 19

Mothers present how2

Answer 19

Flu like illness

Asymptotic fecal or vaginal carriers

Question 20

How the listeria transmitted to baby3

Answer 20

Transplacentally
Ascending
Vag.canal

Question 21

Complication of transplacenta infection 3

Answer 21

Abortion
Preterm delivery
Fetal infection

Question 22

Characteristic symptom

In listeria infection

Answer 22

Preterm with Meconium

Question 23

Listeria early 4 and late infection types

Answer 23

Pneumonia
Sepsis
Rash
Meningitis

Late-meningitis

Question 24

Ecoli and gram neg source

Answer 24

Fecal and vaginal

Question 25

Sticky eye in neonates when | And tx

Answer 25

3-4 day | Clean with NS O water

Question 26

Eye discharge only organisms and treatment

Answer 26

Streptococci , staphylococci | Rx-topical Antibiotics

Question 27

Eye swelling and discharge organisms 2

Answer 27

Gonnorrhea | Chalmedia trachimatis

Question 28

Gonnococal infection present when Ix Rx Complication

Answer 28

<48hrs Gram stain and culture Iv AB Blindness

Question 29

Chlamydia present when 2 Ix Rx

Answer 29

Commonly in 1-2 weeks, some time at birth Immunofluracent staining Oral erythromycin 2 weeks

Question 30

Umbilical infection rx | Um granuloma rx

Answer 30

Systemic AB | silver nitrate or copper sulphate

Question 31

HSV Infection sources

Answer 31

Birth canal | Ascending

Question 32

HSV infection risk high when in primary or recurrent

Answer 32

Primary

Question 33

HSV present when | How4

Answer 33

Up to 4 weeks | Lesions in skin ,eye ,encephalitis, disseminated

Question 34

Rx in HSV

Answer 34

Acyclovir

Question 35

If mother has HSV lesion in genitalia delivery how | If recurrent infection deliver how

Answer 35

El lscs | Vaginally as transmission risk less after treating mother

Question 36

Hep B which baby's should receive vaccination and when | Who should be given immunoglobulin and when

Answer 36

Mothers HBs Ag pos Shortly after birth E Ag pos but no AB in mother In first day