Neonate Flashcards

(44 cards)

1
Q

Define preterm

A

A birth that occurs before 37 completed weeks of gestation

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2
Q

Define term

A

A birth between 37 weeks and 42 weeks of gestation

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3
Q

Define post term

A

A birth that occurs after 42 completed weeks of gestation

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4
Q

Over half of deaths in childhood occur when and are strongly influenced by which factors?

A
  • in the first year
  • strongly influenced by pre-term delivery and low birth weight
  • other risk factors include; mothers maternal age, smoking and disadvantaged circumstances
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5
Q

Which babies are most at risk for death in the first year?

A
  • black or black british, asian or asian british >50% higher risk
  • teenage mother and mothers over 40 39% higher risk
  • mothers living in poverty 57% higher risk
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6
Q

Name causes of preterm birth from most to least common

A
  • spontaneous preterm labour - multiple pregnancy
  • preterm prelabour rupture of membranes
  • pregnancy associated hypertension
  • cervical incompetence / uterine malformation
  • antepartum haemorrhage
  • intrauterine growth restriction
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7
Q

Name risk factors for pre term birth

A
  • > 2 preterm deliveries previously (70% risk)
  • abnormally shape uterus increases by 19%
  • 9 times more likely if multiple pregnancy
  • interval of <6 months between pregnancies
  • conceiving through in vitro fertilisation
  • smoking, drinking alcohol and using illicit drugs
  • poor nutrition, some chronic conditions
  • multiple miscarriages or abortions
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8
Q

Name common problems of prematurity

A
  • temperature control
  • feeding / nutrition
  • sepsis
  • system immaturity / dysfunction; RDS, patent ductus arteriosus, intraventricular haemorrhage, necrotising enterocolitis
  • others; metabolic, ROP
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9
Q

Why is thermal regulation ineffective in the neonate?

A
  • low BMR
  • minimal muscular activity
  • subcutaneous fat insulation is negligible
  • high ratio of surface area to body mass
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10
Q

Name reasons why there is an increased risk of nutritional compromise in the neonate

A
  • limited nutrient reserves
  • gut immaturity
  • immature metabolic pathways
  • increased nutrient demands
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11
Q

When can neonatal sepsis be acquired?

A
  • early onset; mainly due to bacteria acquired before and during delivery
  • late onset; acquired after delivery (nosocomial or community sources)
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12
Q

Name organisms causing neonatal sepsis

A

Early onset;

  • group B streptococcus
  • gram negatives

Late onset;

  • coagulase negative staphylococci
  • gram negatives
  • staph aureus
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13
Q

Name respiratory complications of prematurity

A
  • respiratory distress syndrome (RDS)
  • apnoea of prematurity
  • bronchopulmonary dysplasia
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14
Q

Describe respiratory distress syndrome - hyaline membrane disease

A
  • primary pathology; surfactant deficiency, structural immaturity
  • secondary pathology
  • alveolar damage; formation of exudate from leaky capillaries, inflammation, repair
  • common; 75% of infants born before 29 weeks, 10% in infants born after 32 weeks
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15
Q

Describe the clinical features of RDS

A
  • respiratory distress
  • tachypnoea; grunting, intercostal recessions, nasal flaring, cyanosis
  • worsen over minutes to hours
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16
Q

Describe the management of RDS

A
  • maternal steroid
  • surfactant
  • ventilation; invasive / non-invasive
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17
Q

Name the grades and outcomes of intraventricular haemorrhage

A
  • Grade 1 and 2; neurodevelopmental delay up to 20%, mortality 10%
  • grade 3 and 4; neurodevelopmental delay up to 80%, mortality 50%
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18
Q

What is the normal weight for a term newborn?

A
  • 2.5 kg - 4 kg
  • over 4kg large for gestational age
  • under 2.5kg small for gestational age
19
Q

What is the average daily weight gain of the neonate in the 3rd trimester?

20
Q

How much iron is transferred across the placenta?

A

Enough to last the first year of life

21
Q

Name causes of placental insufficiency

A
  • pregnancy induced hypertension
  • pre-eclampsia
  • mother used drugs or alcohol during pregnancy
22
Q

What is the apgar score a measure of?

A

A measure of perinatal adaptation

23
Q

Describe haemorrhagic disease of the newborn

A
  • rare 2:1,000
  • potential mortality / morbidity; GI, lungs, CNS
  • vitamin K is given in order to prevent at birth; IM or oral
  • spontaneous bleeding and coagulopathy if untreated
24
Q

Name the screening tests performed on the new born

A
  • newborn examination
  • universal hearing screening
  • hip screening
  • blood spot day 5; cystic fibrosis, haemoglobinopathies, metabolic disease
  • thyroid function testing
25
How does the new born blood spot aid a CF diagnosis?
- not a direct diagnosis - blood sport would be abnormal for immuno-reactive trypsin - refer for further tests
26
What is looked for on the head in the new born exam?
- OFC - overlapping sutures (normal after birth) - fontanelles - ventouse / forceps marks - moulding - cephalohematoma - caput succedaneum
27
What is a cephalohematoma ?
- common - bruising or bleeding between bone periosteum and the epicardial aponeurosis - limited to the suture line - often parietal - can take a while to heal - can calcify
28
What is caput succedaneum?
- swelling and oedema of the outer layer of the skin - can be dramatic - leaves quickly, within 48 hours
29
What is looked for in the eyes in the new born exam?
- size - red reflex (if absent, cataract until proven otherwise) - conjunctival haemorrhage - squints (frequent) - iris abnormality
30
What is looked for in the ears in the new born exam?
- position - external auditory canal - tags / pits - folding - family history of hearing loss
31
What is looked for in the mouth in the new born exam?
- shape - philtrum (if smooth can be a sign of foetal alcohol syndrome) - tongue tie - palate (teeth should be removed) - neonatal teeth - ebsteins pearls - sucking / rooting reflex
32
What is looked for in the face for the new born exam?
- facial palsy | - dysmorphism
33
What respiratory signs are looked for in the new born exam?
- chest shape - nasal flaring - grunting - tachypnoea - in drawing - breath sounds
34
What cardiovascular signs are looked for in the new born exam?
- colour / saturation (SaO2) - femoral pulse - apex - thrills / heaves - heart sounds
35
What abdominal signs are looked for in the new born exam?
- moves with respiration - distension - hernia - umbilicus - bile stained vomiting - passage of meconium - anus
36
What genitourinary signs are looked for in the new born exam?
- normal passage of urine - normal genitalia - undescended testes - hyposapdius
37
What MSK signs are looked for in the new born exam?
- movement and posture - limbs and digits - spine - hip examination
38
What neurological signs are looked for in the new born exam?
- alert, responsive - cry - tone - posture - movement - primitive reflexes; suck, rooting, moro, ATNR, stepping, grasp
39
Describe the apgar score
- out of 10 - 2 for heart rate - 2 for resp effort - 2 for tone - 2 for colour - 2 for response
40
What are the normal ranges for vital signs of the new born?
- RR; 40 - 60 / minute - HR; 120-140 BPM - cap refill - 2-3 seconds - SaO2 95%
41
What is the blood volume of a newborn?
80ml per kilo
42
Describe therapeutic chemotherapy
- total body cooling - cooled to 33 and a half degrees for 72 hours - shown to be protective for babies with ischaemia, can help prevent lasting damage
43
Name common bacteria for infection of the new born
- group B streptococcus (most common) - e coli - listeria mycocytogenes - staph aureus - staph epidermidis
44
Name common viruses infecting the new born
- cytomegalovirus - parvovirus - herpes viruses - enteroviruses