Neonatology Flashcards

(32 cards)

1
Q

what is the normal BP, RR and HR of a full term newborn?

A

BP:
- 1hr old: 70/44
- 1 day old: 70(+/-9)/42(+/-12)
- 3 days old: 77(+/-12)/49(+/-10)

RR: 30-60/min

HR:
- normal: 120-160bpm
- tachycardia: > 160bpm
- bradycardia: < 100bpm

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2
Q

how do newborn babies thermoregulate?

A
  • Maternal thermoregulation in the womb.
  • Newborn babies lack shivering thermo genesis thus need a metabolic production of the heat.
  • Brown fat well innervated by sympathetic neurons.
  • Cold stress leads to lipolysis and heat production.
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3
Q

what are some causes of a baby being born small for dates?

A
  • maternal: smoking, maternal pre-eclamptic toxemia (PET)
  • foetal: chromosomal (e.g. Edward’s syndrome), infection (e.g. CMV)
  • placental e.g. abruption
  • twin pregnancy
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4
Q

what are some common problems that can happen to a baby born small for dates?

A
  • perinatal hypoxia
  • hypoglycaemia
  • hypothermia
  • polycythaemia
  • thrombocytopenia
  • hypoglycaemia
  • GI problems
  • RDS, infection
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5
Q

What are some long-term problems associated with being born small for dates?

A
  • hypertension
  • reduced growth
  • obesity
  • ischaemic heart disease
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6
Q

what is considered pre-term and extremely pre-term?

A
  • pre-term < 37w
  • extremely preterm < 28w
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7
Q

what is considered a low, very low and extremely low birth weight?

A
  • low: < 2500g
  • very low: < 1500g
  • extremely low: < 1000g
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8
Q

how can respiratory distress syndrome be prevented and treated?

A
  • prevention: antenatal steroids
  • early treatment: surfactant
  • early extubation: non-invasive life support (N-CPAP), minimal ventilation (low tidal volume and good inflation)
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9
Q

hopw are minor respiratory problems such as apnoea/irregular breathing and desaturations in a pre-term infant treated?

A
  • caffeine
  • N-CPAP
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10
Q

jaundice treatment

A
  • treat underlying cause
  • hydrate
  • phototherapy
  • exchange transfusion
  • immunoglobulin
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11
Q

how is cold stress treated?

A
  • dry quickly
  • remove wet linens
  • use warm towels/blankets
  • provide radiant warmer heat
  • use heated/humidified oxygen
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12
Q

what is considered hypoglycaemia in a neonate?

A

blood sugar < 2.0mmol/l

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13
Q

what are symptoms/signs of hypoglycaemia in a neonate?

A
  • jitteriness
  • temperature instability
  • lethargy
  • hypotonia
  • apnoea, irregular respiration
  • poor sucking/feeding
  • vomiting
  • high pitched or weak cry
  • seizures
  • asymptomatic
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14
Q

why is it very important that the femoral pulses are palpated during the newborn examination?

A
  • absent/weak femoral pulses can indicate coarctation of the aorta
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15
Q

what could the presence of spinal dimples indicate?

A
  • can reveal a more serious abnormality involving the spine and/or spinal cord, such as spina bifida occulta which is the least serious form of spina bifida +/- tethered cord
  • if the dimple is large, or midline, high, or with other cutaneous markers (e.g. hairy tuft) > spinal imaging
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16
Q

developmental dysplasia of the hip (DDH) tests

A
  • Barlow
  • Ortolani
17
Q

DDH treatment

A
  • goal: relocate head of femur to acetabulum so hip develops normally
  • Pavlik harness
  • surgical reduction
18
Q

neonatal sepsis treatment

A
  • admit NNU
  • partial septic screen (FBC, CRP, blood cultures) and blood gas
  • consider CXR, LP
  • IV penicillin and gentamicin 1st line
  • 2nd line IV vancomycin and gentamicin
  • add metronidazole if surgical/abdominal concerns
  • fluid management and treat acidosis
  • monitor vital signs and support respiratory and CV systems as required
19
Q

what are the 5 most common causative organsims in neonatal sepsis?

A
  • group B streptococcus
  • e.coli
  • listeria
  • coag-neg staphylococcus (if lines in situ)
  • haemophilus influenzae
20
Q

what is considered early and late onset GBS sepsis?

A
  • early: birth to 1 week
  • late: up to 3 months
21
Q

GBS sepsis complications

A
  • meningitis
  • DIC
  • pneumonia and respiratory collapse
  • hypotension
  • shock
22
Q

what are some causes of RDS?

A
  • sepsis
  • TTN: transient tachypnoea of the newborn
  • meconium aspiration
23
Q

Meconium aspiration risk factors

A
  • post dates
  • maternal diabetes
  • maternal hypertension
  • difficult labour
24
Q

meconium aspiration investigations

A
  • blood gas
  • septic screen
  • CXR
25
differential cardiac diagnoses for the 'blue baby'
5 Ts: - truncus arteriosus - TGA - tricuspid atresia - ToF - TAPVD
26
how is neonatal hypoglycaemia treated?
- admission to NNU - monitor blood glucose - start IV 10% glucose - increase fluids - increase glucose concentration - glucagon - hydrocortisone
27
what are some causes of birth asphyxia?
- placental problem - long, difficult delivery - umbilical cord prolapse - infection - neonatal airway problem - neonatal anaemia
28
describe the stages of birth asphyxia
1st: - within minutes - cell damage occurs with lack of blood flow and O2. 2nd: - reperfusion injury - can last days or weeks - toxins are released from damaged cells
29
what are some causes of failure to pass stool in a neonate?
- large bowel atresia - imperforate anus +/- fistula - Hirchsprungs disease - meconium plug - meconium ileus, think cystic fibrosis
30
describe neonatal abstinence syndrome (NAS)
- withdrawal from physically addicitve substances taken by the mother in pregnancy such as opioids, benzos, cocaine, amphetamines
31
neonatal abstinence syndrome treatment
- comfort e.g. swaddling - morphine - phenobarbitone
32
hypoxic ischaemia encephalopathy treatment
- early supportive manahement - cooling of baby - treat seizures - fluid restriction