Neonatology Flashcards

(50 cards)

1
Q

T/F: Mothers with prior pregnancies with + GBS screen should be treated prophylactically automatically on current pregnancy

A

False- only if prior infant had invasive GBS disease

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2
Q

What should women receive if GBS+ and had anaphylactic response to penicillin?

A

Clindamycin

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3
Q

What is the biggest risk factor for preterm delivery?

A

Prior preterm delivery

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4
Q

What test can be done to confirm the diagnosis of premature rupture of membranes (PROM)?

A

Nitrazine paper test

Amniotic fluid is pH 7-7.3 compared to vaginal pH of 3.8-4.2

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5
Q

When should fetal pulmonary maturity testing be done?

A

Between the weeks of 32-39 weeks gesttaion

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6
Q

If a mom is PROM, what is the goal gestational age to be reached for delivery if baby’s lungs are mature?

A

34 weeks

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7
Q

What is HELLP?

A

Hemolysis
Elevated liver enzymes
Low platelets

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8
Q

What is an important measure of incidence of malformations associated with maternal DM?

A

Degree of hyperglycemia PRIOR TO conception

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9
Q

Which type of deceleration prenatally is associated with uteroplacental insufficiency?

A

Late deceleration

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10
Q

What is the only APGAR association to worsened mortality and severe neurologic sequelae?

A

APGAR < 3 at 15 minutes of life

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11
Q

How do you estimate the length of an ETT for a neonatal intubation?

A

6 + weight in kg

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12
Q

What are the stages of ear form development in the newonate?

A

24-33 weeks: flat, shapeless
34-35: superior incurving
36-38: upper 2/3 incurving
> 39: well defined incurving to lobe

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13
Q

What are the stages of sole crease development by gestational age?

A
24-31: no anterior sole creases
32-33: 1-2 anterior sole creases
34-35: 2-3 anterior sole creases
36-37: creases covering 2/3 of anterior sole 
38-41: heel creases present 
> 42: deep creases on entire sole
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14
Q

What are the stages of lanugo presence by gestational age?

A

entire body: 22-32 weeks
absent from face- 33-37 weeks
present on shoulders only - 38 - 41 weeks
none present > 42 weeks

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15
Q

What is the name of the rash in the newborn defined as an ulcerated, noninflammatory, well-demarcated congenital absence of skin?

A

Aplasia cutis congenita

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16
Q

When does the anterior fontanelle close?

A

Between 9-18 months

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17
Q

When does the posterior fontanelle close?

A

By 4 months age

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18
Q

Which type of neonatal skull fracture has the worst prognosis?

A

Basilar skull fracture

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19
Q

What is the likely organism responsible for conjunctival purulence in the first 2-5 days of life?

A

Neisseria Gonorrhea

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20
Q

What is the likely organism responsible for conjunctival purulence in the first 5-14 days of life?

A

Chlamydia trachomatis

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21
Q

What is the treatment of chlamydia conjunctivitis?

A

Erythromycin x 14 days

22
Q

What is the treatment of gonorrhea conjunctivitis?

A

3rd generation cephalosporin

23
Q

What is a benign mass on the floor of the mouth due to dilatation of the salivary gland?

24
Q

T/F: Coughing int he newborn is a normal finding

A

False, almost never normal

25
What maternal diagnosis should be considered in a neonate with complete heart block?
SLE
26
What is the pressure difference betwen upper and lower extremities in coarctation?
>20 mm Hg
27
What is the likely diagnosis in a neonate with sudden onset gross hematuria, unilateral/bilateral flank masses and thrombocytopenia?
Renal vein thrombosis
28
Are omphaloceles are gastroschisis more likely to be associated with a genetic syndrome?
Omphalocele
29
What are common risk factors for gastroschisis?
Maternal young age and drug use
30
What is the possible immunodeficiency associated with delayed umbilical cord separation?
LAD (Leukocyte adhesion deficiency)
31
What is considered an abnormally small penile length in a neonate?
< 2.5cm
32
What is the syndrome: - Pancytopenia (aplastic anemia) - Skin findings (cafe au lait) - Skeletal anomalies - Microcephaly - Thumb hypoplasia
Fanconi anemia
33
What is the syndrome: - Hypoplastic anemia, low Hgb and retic count - Short stature - Limb abnormalities
Diamond Blackfan anemia
34
What is the syndrome: - normal/increased WBC, normal Hgb - Thrombocytopenia - Absent bilateral radii
Thrombocytopenia with absent radii (TAR) syndrome
35
What should be given to babies born to mothers with HbsAg positive? How soon after birth?
HBIG and Hep B vaccine, within 12 hours
36
What is considered a pass on the CCHD screen?
Sats > 95% in pre and post ductal sats | Sats =< 3% difference between pre and post ductal
37
Which antiepileptic increases the risk of fetal hydantoin syndrome?
Phenytoin
38
What is the risk of maternal use of methotrexate in pregnancy?
Limb defects and craniosynostosis
39
What is the risk associated with maternal use of ACE-inhibitors during pregnancy?
Renal dysgenesis, oligohydramnios and skull ossification defects
40
What is the side effect of maternal use of streptomycin during pregnancy?
Hearing loss in infant
41
What is the effect of maternal tetracycline use after 20 weeks gestation in neonate?
Tooth discoloration
42
What is the effect of maternal warfarin use during pregnancy on the neonate?
Fetal warfarin syndrome: Nasal hypoplasia and stippled epiphyses
43
What are the three categories of FAS abnormalities in the neonate?
Facial abnormality + Growth deficiency + Cognitive abnormality
44
What is the most common cause of intellectual disability?
FAS
45
What congenital infection is associated with abnormal teeth/bones, ID and proteinuria?
Syphilia
46
What is the etiology of RDS in an IDM?
Insulin blocks enzymes necessary for synthesis of precursor of surfactant
47
Which test on the amniotic fluid can be done to evaluate for lung maturity?
L/S ratio
48
What is a side effect of iNO therapy in pulmonary hyprtension?
Methemoglobinemia
49
What is the finding of CT with intraabdominal calcifications concerening for?
Meconium peritonitis
50
What is the impact of phenobarbital on the development of Crigler Najjar?
Phenobarb induces expression of enzyme in patients with TII Crigler Najjar, decreases serum bili level