Neoplasms Flashcards
(50 cards)
Risk factors for breast cancer
Nulliparity
Early menarche
Late menopause
Postmenopausal combo HRT
S/S of breast cancer
Painless breast mass
Fixed
Hard
Irregular margins
MC location of breast cancer
Upper outer quadrant
S/S of Paget’s disease of the breast
Itching, pain, and burning of breast
Superficial erosion or ulceration
Bloody nipple discharge
Diagnosis of Paget’s disease of the breast
Full-thickness biopsy
Treatment of Paget’s disease of the breast
Mastectomy
S/S of inflammatory carcinoma
Orange peel sign (peau d’orange)
Brawny edema
Treatment of inflammatory breast cancer
Multiple chemo rounds
Followed by radiation and surgery
Screening for breast cancer
Mammogram annually after 40
Diagnosis of breast cancer
Core needle biopsy
Which has better outcomes, ER- or +?
+
If ER+ ___
Raloxifene or Anastrozole
Worst type of breast cancer
Triple negative
CIN types
CIN 1: mild, lower 1/3
CIN 2: moderate, lower 2/3
CIN 3: severe, over 2/3
Gardasil vaccine
Recommended at age 11-12 (from Hannah’s quizlet)
Age 9-14: 2-dose - 0 months and 6-12 months OR 3-dose - 0, 2, 6 months
Age 15-45: 3-dose (0, 2, 6 months)
(from Epperly’s slides)
Cervical cancer screening
Start at age 21
Pap every 3 years until 30
Pap & HPV every 5 years from 30-65 OR pap only every 3 years
When to stop screening for cervical cancer?
65+
No hx of moderate or severe dysplasia
3 negative paps in a row
Pap smear results
ASCUS (undetermined significance)
ASCH (cannot exclude high-grade lesion)
LGSIL (low-grade squamous intraepithelial, corresponds to CIN 1)
HGSIL (high-grade squamous intraepithelial, corresponds to CIN 2/3)
AGC (atypical glandular cells)
Treatment of ASCUS
Repeat paps every 6 months until normal
Next step for LGSIL and HGSIL
Colposcopy and biopsy
Treatment of CIN 1
Expectant management
2 paps every 6 months or pap & HPV test every 6 months
Treatment of CIN 2 or 3
Surgical procedure
HPV strains most correlated with cervical cancer
16, 18, 45
S/S of cervical cancer
Abnormal vaginal bleeding
*Postcoital bleeding
