Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Abdomen 2 > Neoplastic Pancreas > Flashcards

Neoplastic Pancreas Flashcards

0
Q

Etiologies of Von Hippel-Lindau Syndrome

A

Autosomal dominant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Etiologies of Polycystic Kidney Disease

A

Autosomal dominant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Characteristics of pt’s with Von Hippel-Lindau Syndrome

A
  • 75% have pancreatic cysts
  • Neuroendocrine tumors - related to, or involving, the interaction between the nervous system and the hormones of the endocrine glands
  • Renal cell carcinoma
  • Eye tumors
  • Brain/spinal cord lesions
  • Pheochromocytomas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clinical signs of Von Hippel-Lindau Syndrome

A
  • Asymptomatic
  • Pain/pressure/jaundice if obstruction of the bile ducts occurs
  • HTN w/ pheochromocytomas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Sonographic appearance of Von Hippel-Lindau Syndrome

A
  • Single or multiple of various sizes
  • Size and number of cysts can increase with age
  • 72% found in patient at autopsy
  • 25% found in patients with ultrasound
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What percentage of pancreatic cysts does neoplastic cysts make up?

A

10-15%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the 2 types of neoplastic cysts?

A
  • Microcystic adenoma (serous)

- Macrocystic adenocarcinoma (mucinous)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where is Microcystic Adenoma Found?

A
  • Rare
  • Benign
  • Elderly women
  • No potential for malignency
  • Seen in patients with Von Hippel-Lindau Syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where is Macrocystic Adenocarcinoma Found?

A
  • Rare
  • Significant malignancy potential
  • Slow growing
  • 35-60% found in body and tail, only 5% found in head
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Clinical Signs of Microcystic Adenoma (Cystadenoma)

A
  • Asymptomatic
  • More frequent in females
  • People over 60yo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Labs associated with microcystic adenoma (cystadenoma)

A
  • None specific

- Increase in amylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sonographic appearance of microcystic adenoma (cystadenoma)

A
  • Large, well circumscribed lesion with multiple tiny cysts

- Cyst size varies from 1-20mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Clinical signs of macrocystic adenocarcinoma (cystadenoma)

A
  • Non-specific abd. epigastic pain
  • Palpable mass
  • Concurrent disease, such as diabetes, calculous disease of biliary tree, arterial hypertension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Sonographic appearance of macrocystic adenocarcinoma (cystadenoma)

A
  • Well circumscribed
  • Thin or thick walled
  • Uni- or multi-loculared
  • > 20mm in size
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Etiology of Adenocarcinoma

A
  • Most common primary tumor of the pancreas
  • 60-70% occur in the head of pancreas
  • Involves the EXOCRINE!!! portion of gland
  • > 90% of all malignant tumors of the pancreas
  • 4th leading cause of cancer death, behind lung, breast, & colon
  • Rare before 40yo. 2/3 present after 60.
  • More common in males!!!
  • Poor prognosis. Mean average survival time is 2-3 months
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clinical signs of Adenocarcinoma

A
  • Symptoms appear late in disease
  • Pain radiating to back, dull ache in mid epigastrium
  • Painless jaundice
  • N/V
  • Weight loss!!!!!
  • Clay colored stools
16
Q

Labs associated with Adenocarcinoma

A

-Increased bilirubin (direct or indirect???)

17
Q

Etiology of Islet Cell Tumors

A
  • Endocrine!!!
  • Neuroendocrine tumors
  • Of, or relating too, or involving the interaction between the nervous system and the hormones of the endocrine glands
18
Q

Characteristics of Non-Functioning Islet Cell Tumors

A
  • Make up 1/3 of all islet cell tumors
  • 92% of these are malignant
  • Slow growth rate
  • Typically no distant metastasis
19
Q

Characteristics of Functional Islet Cell Tumors

A
  • Typically benign

- Produce symptoms

20
Q

Types of Functional Islet Cell Tumors

A
  • Insulinoma
  • Gastrinoma
  • Glucagonoma (highly malignant)
  • Vipoma (highly malignant)
  • Somtostinoma
  • Last 3 are rare
21
Q

Clinical signs of Insulinoma

A
  • Most common islet cell tumor (60%)
  • 10% will be malignant
  • Produces too much insulin
  • Pt will present with hypoglycemia
22
Q

Labs associated with insulinoma

A

-Low glucose

23
Q

Sonographic appearance of insulinoma

A

-Well defined, small, hypoechoic mass

24
Q

Clinical signs of gastrinoma

A
  • 2nd most common functional tumor (18%)
  • Higher malignancy rate of 25-60%
  • Produces a syndrome known as Zollinger-Ellison syndrome
  • Pt presents with diarrhea and peptic ulcer disease (PUD)
  • Mean age at presentation is 50yo
25
Q

What is cystic fibrosis?

A
  • Common hereditary disease which affects the entire body causing progressive disability and often early death.
  • Name refers to the characteristic scarring (fibrosis) and cyst formation within the pancreas, first recognized in the 30s
26
Q

Sonographic appearance of cystic fibrosis

A
  • Increased echogenicity - caused by fibrosis and fatty replacement
  • Cysts are very tiny and unresolvable for US

Abdomen 2 (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions