Nephron Flashcards
(22 cards)
Nephron
Microscopic independent filtering units called nephrons, nephron filter, water and solute from blood.
6 structures in the nephron
Glomerulus,
bowman capsule,
proximal tubule,
loop of henle,
distal tubule,
collecting duct
Glomerulus
A microscopic ball of capillaries
Bowman’s capsule
Cup like structure that filters and collects the leaking fluids forced out of the glomerulus
Loop of henle
Continuation of the proximal that dips down into the renal medulla divided into two parts the descending loop and the ascending loop
Distal tubule
As the ascending loop of Henle returns to the Renal cortex, it turns into the distal tubule
Collecting duct
Collecting ducts funnel urine into the renal pelvis where it is collected and leaves the kidney via the ureter several nephrons drain urine into a single collecting duct
Afferent arteriole
A small branch of the Renal artery this Effron arterial enters the nephron first with unfiltered blood
Efferent arteriole
Filtered blood leaves in nephron through the Efferent arteriole which turns into a capillary network that surrounds the rest of the nephron
Renal cortex
The outermost region of the kidney this is the site of filtration of wastes from blood
Renal medulla
The middle region which regulates salt/water balance of blood
Order of blood flow in each nephron
Renal artery
Afferent arteriole
Efferent arteriole
Capillary network
Renal vein
Renal artery
Artery that brings unfiltered blood to each kidney
Capillary network
After going through the glomerulus, the efferent arteriole turns into a capillary network that surrounds the rest of the nephron
Renal vein
That takes up the filtered blood away from the kidney
3 processes of the nephron
Glomerular filtration
Tubular reabsorption
Tubular secretion
Glomerular filteration
Has blood enters the glow Mirlis, which is encased by the Bowmans capsule the blood entering the glomerulus is under pressure and the walls of the glomerular capillaries are semi permeable much of the plasma, and the solute dissolved in the plasma leave the blood through spaces in the glomerular capillaries the blood and dissolved materials that are filtered from the blood are known as filtrate plasma proteins, and blood cells are too large to pass through glomerulus and the membrane of the Bowmans capsule so they remain in the blood of the efferent arteriole
Tubular reabsorption
Happens in the proximal tubule is where majority of the reabsorption of the filtrate happens, but also happens within different parts of the nephron like the distal tubule or the loop of Henley or collecting duct but majority in proximal tubule
Tubular secretion
Happens in the distal tube, where additional substances pass from the blood into the filtrate through a process called secretion. These substances can include uric acid ammonia, some drugs, and toxic materials.
Some secretion happens in the proximal tubule but very little so majority of secretion happens in the distal tubule
The pH of blood is also adjusted by hydrogen ions that are separated from the blood into the filtrate
Proximal tubule
Thin hollow tube that leads out of the Bowman’s capsule
Renal pelvis
Hollow funnel like chamber that collects urine and directs it to the ureter
Full flow of filtrate
Efferent arteriole into proximal tubular, which is the site of reabsorption of ion salts, etc., back into the blood infiltrate, then goes down into the descending loop of Henley, where it reaches the medulla, and as it gets saltier, more water gets drawn out and reabsorbed the bottom of loop of henly is where soltute concentration is at peak on the way up the ascending loop of henly salt becomes permeable, and water is not permeable, which means salt absorption happens in this area as it goes up and the interstitial fluid is less salty as it goes up then into the distal tubule where tubule secretion occurs as wastes get transferred into the filtrate from the blood, and also very little salts and ions get reabsorbed at this stage, then going down into the medulla into the collecting duct concentration of the interstitial fluid gets more salty, which leads to more water getting drawn out before it becomes urine. Then that urine goes into the renal pelvis down to the ureter into the bladder through the internal sphincter into the urethra outside the external sphincter.