Flashcards in Nepritic syndrome - IgA nephropathy Deck (11):
What is IgA nephropathy?
The deposition of polymeric underglycosylated IgA in the mesangial matrix. (most common nephropathy worldwide)
What disease is considered a characteristic form of IgA nephropathy?
What disease also shows and increase in incidence of IgA nephropathy?
Celiac disease and chronic liver disease who have decreased hepatobiliary clearance.
What diseases can IgA nephropathy be secondary to?
1.inflammatory bowel disease
In what subset of patients is IgA nephropathy most common?
Children and young males
In what race is IgA nephropathy most prevalent?
May have genetic predisposition or be familial
What infections usually trigger IgA nephropathy?
Upper respiratory or gastrointestinal tract infection (mucosal infection).
How soon after infection does nephritic urinary sediment occur?
1 or 2 days after infection
What are the findings in IgA on immunoflurescence?
Mesangial IgA deposits with C3 and properdin
What is the treatment for IgA nephropathy?