Nerve Malformations Flashcards

(28 cards)

1
Q

This category of drugs in which studies have shown no risk to the fetus

A

Category A

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2
Q

This category of drugs w/ no human studies but animal studies have shown effects of fetus

A

Category B

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3
Q

This category of drugs has studies that are inadequate in both human and animal to show effect the fetus

A

Category C

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4
Q

This category of drugs defiantly causes harm to the fetus but benefits the mother

A

Category D

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5
Q

This category of drugs causes harm to the fetus with no benefit to the mother

A

Category X

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6
Q

What is a tetrogen?

A

Any agent that can produce congenital malformations

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7
Q

That is a sign?

A

An objective evidence of disease

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8
Q

A Subjective evidence of disease is a what?

A

Symptom

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9
Q

A syndrome is…

A

a set of symptoms and signs that occur together

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10
Q

What is the study of the cause of disease

A

Etiology

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11
Q

The critical period of development for the nervous system

A

3rd-7th week

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12
Q

The critical period of development for the cardiovascular system

A

4th-6th week

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13
Q

The critical period of development for the ears

A

4th-8th week

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14
Q

The critical period of development for the eyes

A

4th-8th week

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15
Q

The critical period of development for the limbs

A

4th-7th week

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16
Q

What are the two kinds of “Trisomy of Y”?

A

47XXY male-Klinefelter’s syndrome and 47XYY- Modified Klinefelter’s

17
Q

Individuals that are 47XXY, have the following symptoms:

A

Tall stature, Normal development, average IQ, Long legs when compared to trunk, chromatin positive

18
Q

Individuals with 47 XYY would have the following symptoms:

A

Tall stature, Normal IQ, Hypertelorism, Long legs, Scanty Facial Hair, Cryptorchism, Chromatic Negative

19
Q

What are the symptoms of of turner’s syndrom

A

Horse shoe kidney, unilateral renal agenesis, lack of breast development, infantile external genitalia, chromatin negative

20
Q

The symptoms of 46 (22q+)

A

Cat-eye syndrome, Anal Atresia, Inferior Coloboma, ASD, Posible mosaic, renal agenesis, agenesis of uterus or Fallopian tubes, reto-vestibular fistula

21
Q

The symptoms of 46 (5p-)

A

Mental retardation, low birth weight, high pitch cry, hypotonia, microcephaly, hypertelorism, simian crease, short metacarpals, cardiac defects, renal agenesis, premature greying of the hair

22
Q

Waht does RAD stand for?

A

Radiation Absorbed Dose

23
Q

What is the standard x-ray radiation does?

A

below 5,000 milli-REM

24
Q

What does REM stand for?

A

Roentgen Equivalent of Man

25
What are some of the effects of radiation damage in the human body?
1) produce free radicals 2) Break and produce new chemical bonds 3) Damage molecules that regulate vital cell processes
26
What is the major risk of radiation to the fetus in the 1st trimester?
Will often cause fetal death while the fetus is most sensitive
27
In the 2nd trimester, what is the risk to the fetus when radiation is applied
The major organ systems are most sensitive and can cause several malformations
28
In the 3rd trimester, what is the risk to the fetus when radiation is applied?
The cell population is severely depleted and can lead to leukemia