Nerves and Synapses Flashcards

1
Q

how does nervous control compare to hormone action

A

nervous control is faster, more precise and shorter
hormone is slower but longer lasting

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2
Q

what does nervous control usually involve

A

receptors (eyes,ear,nose) and effectors (muscles) and an interlinking coordinator

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3
Q

what do receptors respond to

A

a particular type of stimulus
eg. something we see, hear, touch or smell

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4
Q

what do effectors do

A

parts of the body that produce the response eg mammalian muscle

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5
Q

what is the CNS

A

central nervous system which comprises the brain and spinal cord

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6
Q

what are the three types of neurones

A

motor - carry impulse from CNS to effector
sensory- carry impulse from receptors to CNS
connector/association - connects neurones with CNS

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7
Q

what does axon do

A

a nerve fibre that transmits impulses away from the cell body

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8
Q

what is the difference between dendron and dendrite

A

dendrites are very small and numerous extensions that conduct impulses to the dendron
dendron is a part of the fibre carrying impulses to the cell body

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9
Q

what are nodes of ranvier

A

small gaps along the nerve fibre, in the absence of schwann cells

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10
Q

what organelles does the cell body usually contain

A

nucleus, mitochondria, RER, golgi, nissls granules etc

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11
Q

what does resting potential mean

A

at rest the neurone is -70mv inside relative to the outside. the membrane is polarised

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12
Q

what is action potential

A

when rapid depolarisation occurs, causes a change to +40mv inside relative to outside (the action potential occurs)

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13
Q

define the all or nothing law

A

the principle that once the threshold stimulus is reached, the action potential results ie. the action potential either occurs or it does not (only occurs above the critical level

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14
Q

what is the threshold stimulus

A

the level of stimulus a neurone requires before an action potential is produced

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15
Q

how is a nerve impulse propagated

A

as one part of the membrane becomes depolarised, it sets up local (electrical) circuits with the areas immediately adjacent on each side, +ve ions from the depolarised zone pass along the inside of the membrane towards the polarised zone immediately infront.
similarly on the outside +ve ions move back from the still polarised zone into the depolarised zone
it is these processes occurring that cause a wave of depolarisation that moves rapidly along neurone
similar circuits enable resting potential to be restored directly behind action potential

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16
Q

what factors increase the speed of nerve impulses

A

-presents of myelin sheath(acts as an insulator, as it prevents depolarisation)
-thicker diameter of axon - thicker the axon faster the impulse( there is proportionally less leakage of ions in a neurone with a larger diameter making it easier to maintain potential gradients

17
Q

what is saltatory conduction

A

a term which describes how action potentials ‘jump’ from node of ranvier to node of ranvier

18
Q

what is a synapse

A

junction between axon of one neurone and the dendrite of an adjacent neurone

19
Q

what are neurotransmitters

A

a chemical which diffuses across the synapse, carrying information

20
Q

how do they pass into the synapse

A

through synaptic vesicles

21
Q

what is an EPSP

A

an excitatory post-synaptic potential
occurs when positive ions fuse in, making membrane +40 mv, leading to formation of an action potential

22
Q

why are there many mitochondria in the pre synaptic neurone

A

-they are important in manufacturing neurotransmitters
-atp produced by mitochondria is required to allow acetylcholines breakdown products to diffuse out and be resynthesised

23
Q

explain the 4 advantages of synapses

A

1.enable the continuous nature of nerve communication from neurone to neurone throughout the body
2.ensure unidirectionality - neurotransmitters is ONLY made in the presynaptic neurone and neurotransmitters receptors are only in the post synaptic membrane
3. prevents over stimulation of effectors. too many impulses in a short period will exhaust the supply of neurotransmitters- leading to their fatigue
4. provide integration. synapses provide flexibility without them, nervous activity would be little more than a series of reflexes

24
Q

what is summation ***

A

it is important in providing complexity and flexibility that synapses show
eg.

25
what are inhibitory synapses
-make it more difficult for synaptic transmission to occur -make it. ore difficult for an EPSP -inhibitory neurotransmitters lead to an influx of chloride ions in the psm making it even more negative thus producing an IPSP
26
why do we have inhibitory synapses
they reduce input of background stimuli that would clutter up nervous activity in the brain or may prevent reflex actions
27
what is acetylcholine
the primary neurotransmitters substance in the cns if vertibrates
28
what is GABA
a neurotransmitter reached at inhibitory synapses has many roles including helping reduce anxiety and panic attacks trough a damping down of nerve pathways of the brain
29
what effect does nicotine have on synapses
stimulates release of acetylcholine and other neurotransmitters making action potential more likely
30
what effect does curare have on synapses
blocks receptors at neuromuscular junctions preventing synaptic transmission (loss of muscular function
31
what effect do opioids have on synapses
block calcium channels in pre synaptic neurone less transmitter substance is released and action potential is less likely opioids and related compounds can provide pain relief by reducing impulses coming from pain receptors