nervous and intro to genetics Flashcards

1
Q

Making connections to the world from the body (reacting to stimuli) this is called

A

irritability

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2
Q

Organizing and storing information is

A

conductivity

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3
Q

Produce movements

A

effectors

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4
Q

CNS make up

A

brain, spinal cord, neurons cluster in nuclei, axons are bundles in tracts/fasciculi

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5
Q

PNS

A

cranial nerves, spinal nerves, carries messages to and from the CNS
neurons cluster in ganglia, axons are bundles as nerves

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6
Q

Glial cells are ____ cells

A

support cells

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7
Q

Grey matter is composed of

A

cell bodies and dendrites

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8
Q

white matter is composed of

A

axons

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9
Q

Soma =
Dendrites=
axon=

A

Soma= cell bosy, responsible for reception and integration of information
neurons= processes that recieve information
axon= conducts information away from the cell via and action potential or nerve impulse

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10
Q

Multipolar:
bipolar:
pseudounipolar:

A

multipolar: many dendrites, one axon (motor)
bipolar: one dendrite, one axon (special senses)
pseudounipolar: one nerve process (sensory ganglia of spinal and cranial nerves)

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11
Q

PNS neurons cluster within ____

A

ganglia.

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12
Q

An area where gray matter forms a layered surface that covers some part of the CNS is referred to as a _____

A

cortex

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13
Q

The ridges/ folds are called ____
The grooves between gyri are called _____

A

Ridges: gyri
grooves: sulcus

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14
Q

Where do our motor/efferent neurons exist?

A

the ventral/anterior horn

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15
Q

Simply put, what is a peripheral nerve?

A

simply a bundle of axons that are traveling together

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16
Q

Endoneurium:
perineurium:
epineurium:

A

Endoneurium: connective tissue that surrounds and holds together axons into bundles (called fasicles)
perinerium: Layer that surrounds each fasicle
epineurium: all fasciles are bound together and surrounded by

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17
Q

T/F Axons converge and diverge in the fascicles of a nerve

A

T. fasicles are not completely independent

18
Q

Simply put, what are cranial nerves

A

cranial nerves are nerves that emerge from the brainstem
there are 12 cranial nerves

19
Q

The ventral root is (efferent or afferent) only
the dorsal root is (efferent or afferent) only

A

ventral = efferent
dorsal = afferent
BUT both dorsal and ventral rami typically contain both afferent and efferent axons

20
Q

Afferent means

A

neurons that carry information FROM sensory receptors found all over the body towards the CNS

21
Q

Efferent means

A

neurons carry motor information away from the CNS to the muscles and glands of the body in order to initiate an action

22
Q

T/F a peripheral nerve cannot be made up of motor and sensory axons from more than one spinal nerve.

A

FALSE. fascicles split apart and join together as the nerves course through the body, this also ensures that a peripheral nerve is made up of motor and sensory axons from more than one spinal nerve.

23
Q

All of our blood to our brain will be derived from two specific arteries

A
  1. the internal carotid = anterior circulation
  2. Vertebral artery = posterior circulation
24
Q

Lateral aspect of the cerebrum is supplied by the

A

middle cerebral artery

25
The medial aspect is supplied by the
both anterior cerebral artery and posterior artery
26
Posterior intercostal aa that branch from the aorta and then divide into segmental spinal arteries. These then give off_______ aa that supply the _________ and the roots that form it.
these give off RADICULAR AA that supply the spinal nerve and the roots that form the spinal nerve. The radicular arteries will also contribute to the anterior spinal a.
27
An aneursym
weakening of the artery wall
28
occluded vessels
development of a plaque within the lumen of a vessel
29
aterioneous malformations
developmental abnormalities where there is an abnormal connection between arteries and veins
30
Allosomal vs autosomal
Autosomal = on a chromosome that is not a sex chromosome Allosomal= on a sex chromosome
31
What is the simplest form of genetic polymorphism?
Single nucleotide polymorphism= single base (point) mutation
32
T/F a SNP in a coding region can be synonymous
yes. it does not change the amino acid that is produced
33
A SNP in a coding region can be non-synonymous. What is the result of this
1. results in missense or nonsense mutations missense= incorrect amino acid, produces malfunctioning protein nonsense= incorrect sequence causes shortening of protein IT STOPS
34
pleiotropy
multiple traits are effected by one gene.
35
polygenic inheritance
multiple genes affect one trait
36
What is X inactivation
one copy of X chromosome in each cell is silenced. this leads to mosaic phenotypes in heterozygotes
37
epistasis
interaction between genes alleles at one locus are blocked by the presence of a specific allele at another locus
38
Linkage Recombination (meiosis) allows swapping of ______ to increase variation -genes close to each other on the same chromosome are ________ to be inherited together
swapping of genes are much more likely to be inherited together
39
What is linkage disequilibrium
nonrandom association of alleles of different loci basically measures the degree to which alleles at two loci are associated
40
penetrance
is the liklihood that you will develop the disease given that you have the risk allele
41
Expressivity
refers to the severity of the disease if the risk allele is present example: having a cleft lip