nervous system Flashcards
1
Q
clozapine se
A
neutropenia
2
Q
clozapine tests
A
leucocyte and different blood counts
3
Q
quetiapine and amiodarone causes what…
A
qt prolongation
4
Q
clozapine monitoring
A
fbc, blood glucose, lipids
5
Q
amisulpride and furosemide can cause…
A
ventricular arrhythmias
6
Q
metoclopramide is contraindicated in…
A
pts who have had gastro surgery in the past 3-4 days
7
Q
24 yr old female thrown up twice in 2 weeks tx
A
metoclopramide 10mg tds
8
Q
max duration of domperidone
A
7 days
9
Q
first trimester nausea tx
A
nothing
10
Q
cyclizine dose in post surgery female
A
50mg tds
11
Q
how long do the effects of promethazine teoclate work for
A
24 hours
12
Q
most sedative otc brand for motion sickness
A
phenergan
13
Q
most suitable for a 6 hour journey otc brand for motion sickness
A
sominex
14
Q
what percentage of nytol is excreted unchanged in the urine?
A
1%
15
Q
how long does nytol last?
A
1-3 hours
16
Q
zimovane side effect
A
dyspepsia - altered taste
17
Q
what is zopiclone used for
A
insomnia
18
Q
a contraindication for sumatriptan
A
ischaemic heart disease
19
Q
what is tolfenamic acid used for
A
acute migraines
20
Q
topiramate can develop these three conditions
A
acute myopia, secondary angle-closure glaucoma, kidney stones
21
Q
codeine is contraindicated in…
A
tonsil surgery
22
Q
paracetamol dose for 3-5 month old
A
60mg every 4-6 hours
23
Q
paracetamol dose for 6-23 month old
A
120mg every 4-6 hours
24
Q
paracetamol dose for 2-3 year old
A
180mg every 4-6 hours
25
paracetamol dose for 4-5 year old
240mg every 4-6 hours
26
paracetamol dose for 6-7 year old
240-250mg every 4-6 hours
27
paracetamol dose for 8-9 year old
360-375mg every 4-6 hours
28
paracetamol dose for 10-11 year old
480-500mg every 4-6 hours
29
paracetamol dose for 12-15 year old
480-750mg every 4-6 hours
30
what is 1st, 2nd and 3rd line for palliative pain?
morphine, oxycodone, diamorphine
31
what would you add if pt was already on paracetamol, ibuprofen, oramorph 2.5mg/2hrs and pain still not controlled?
morphine mr 15mg bd - match the daily dose of immediate
32
what is the dose of iv paracetamol if pt weighs <50kg (mg/kg)
15mg/kg
33
morphine iv dose is ____ of oral daily dose
half
34
oral morphine is a __th of the dose of oral codeine
10th
35
max breakthrough pain is a __th of total daily dose
1/6th
36
sc dose of morphine is a ___ of oral dose
half
37
which antidepressant drug is not suitable for non adherent people
venlafaxine
38
which antidepressant drug cannot be started immediately if pt wants to switch from ssri
moclobemide
39
which antidepressant class interacts with asian diets
MAOIs
40
which drug interacts with alcoholic mouthwash
disulfram
41
which drug to give if pt continues to be at high drinking risk level after 2 weeks?
nalmefene
42
pt is experiencing symptoms of opioid withdrawal - what do you give?
lofexidine
43
varenicline side effect
suicidal thoughts
44
nicorette max no of sprays daily
64
45
mins one nicotinell gum lasts
30
46
mins one nicorette 15mg inhalator cartridge lasts if used intensely
40 if 10mg - 20 mins
47
max number of nicorette microtabs daily
40
48
when should you discontinue bupropion?
if abstinence is not achieved in 7 weeks
49
what drug is keppra
levetiracetam
50
which aed comes in alcohol and sugar free preparation and should sign the back of an rx
phenobarbital
51
which aed do you take with food
sodium valproate
52
dose of folic acid if pregnant pt is epileptic
5mg
53
drug for a seizure lasting more than 5 mins
iv lorazepam
54
which aed is taken at night
clobazam
55
which aed causes acne
phenytoin
56
target range for phenytoin
10-20mg/l
57
ratio of phenytoin sodium:phenytoin
100:92
58
sodium valproate is contraindicated in...
severe hepatic impairment
59
which aed can cause pancreatitis
sodium valproate
60
which antibiotic does carbamazepine interact with
clarithromycin
61
target range for carbamazepine
4-12mg/l
62
how should you titrate carbamazepine slowly
increase 100-200mg every 2 weeks
63
carbamazepine decreases...
inr
64
primidone undergoes biotransformation into...
phenobarbitone and phenylethylmalonamide
65
which aed do you give if you had seizures and porphyria
clonazepam
66
sertraline increases risk of bleeding when given with...
nsaids
67
which antidepressant interacts with SSRIs
st johns wort
68
escitalopram and quinine can cause...
ventricular arrhythmias
69
olanzapine and citalopram can cause...
dizziness, faint, qt prolongation
70
this antidepressant is safe for mi pts
sertraline
71
which antidepressant can cause suicidal thoughts
citalopram
72
which antidepressant class can cause this electrolyte imbalance and what symptoms does it cause?
SSRI hyponatraemia - drowsiness and confusion
73
which antidepressant if stopped abruptly has the highest risk of withdrawal symptoms?
paroxetine
74
this drug should be taken with caution with sodium in diet
lithium
75
lithium enhances which drug
lisinopril
76
is lisinopril safe for bf
no
77
is lithium safe for bf
no
78
if pt has high levels of lithium which three drugs should you stop
lithium, ace, bendro
79
target range for lithium
0.4-1mmol/l
80
4 side effects of lithium
blurred vision, convulsions, lack of coordination, muscle weakness
81
if you have alcohol with tca it can cause
sleepiness
82
amitriptyline side effect
dry mouth
83
which antidepressant has highest fatality in overdose
amitriptyline
84
how much time should be left between stopping tcas and starting maoi
1 week
85
apomorphine side effect
binge eating
86
cabergoline side effect
sudden onset of sleep
87
risperidone exacerbates...
pd
88
which drug causes fatal liver toxicity
tolcapone
89
list three SNRIs
venlafaxine, tramadol, duloxetine
90
what is buspirone used for
anxiety
91
procyclidine indication
acute dystonia (involuntary muscle movements)
92
drug for motion sickness for 3 hr journey 4 yr old
kwells kids 150mcg
93
teething first line for 3 months over
paracetamol and/or ibuprofen
94
which patch is once a week
buprenorphine
95
name 3 tramadol interactions
carbamazepine
fluoxetine
terbinafine
96
which drug treats both depression and bipolar
lithium
97
scz 1st line
chlorpromazine
98
gabapentin titration dose
300mg day 1, 600mg day 2, 900mg day 3 then increase in steps of 300mg every 2-3 days
99
which antipsychotic increases appetite
olanzapine
100
which two antipsychotics are affected by smoking
olanzapine and clozapine
101
lithium concentration is increased by...
NSAID
102
phenalizine is a ___ that interacts with _____. Action taken?
MAOI. epinephrine. Avoid when pt on MAOI and 14 days after stopping MAOI if stopped for whatever reason.
103
1st line for focal seizures
Carbamazepine or lamotrigine
104
First line for tonic clonic seizures
SV
105
First line for absence seizures
Ethosuximide or sv
106
First line for myoclonic seizures
Sv
107
First line for atonic and tonic seizures
Sv
108
Night time aeds
Lamotrigine
Phenobarbital
Phenytoin
