nervous system histology Flashcards

(63 cards)

1
Q

three functions of nervous system

A

gathers information or sensory input. to detect internal or external stimuli

  1. integration: it processes and interprets sensory input and decides what action should be taken (association neurons or interneurons)
  2. motor output activating effector organs
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2
Q

how many spinal nerves and how many cranial nerves

A

31, 12

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3
Q

a nerve is a collection of ____ i.e. process of a neuron that can generate ____

A

axons, action potentials

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4
Q

neurons are ___ cells that can produce electrical signals

A

excitable

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5
Q

action potential

A

rapid changes in electrical potential of cells created across plasma membrane

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6
Q

neuroglia or glia

A

smaller neurons, supporting cells. important for electrical Mediate or metabolic exchange between vascular system and neurons

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7
Q

neuroglia and glia do NOT

A

generate action potential

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8
Q

are nerve cells or neuroglia are more numerous

A

neuroglia (they can multiply and divide)

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9
Q

special characteristics of neurons

A
  1. extreme longevity (100 yrs)
  2. amitotic (lose ability to divide can’t be replaces)
  3. high metabolic rate (need large supply of O2 and glucose; die in minute without o2)
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10
Q

perikaryon

A

neuron cell body

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11
Q

can you have multiple dendrites or axons

A

dendrites

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12
Q

main function of the perikaryon

A

biosynthetic center of the neuron; no CENTRIOLES because its amitotic; no action potential

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13
Q

nissl bodies

A

free ribosomes that clump together

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14
Q

what helps maintain the shape of neurons

A

microtubules and neurofibrils

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15
Q

axon hillock

A

part of cell body where axon attaches; no organelles

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16
Q

dendrite function

A

main receptive or main input regions. lots of surface area and greatly branched

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17
Q

dendrites are always

A

unmyelinated with no action potential

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18
Q

all organelles except ___ extend into dendrites

A

Golgi

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19
Q

secretory portion of the neuron

A

axon hillocks

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20
Q

anterograde transport

A

substances move from cell body towards axon terminal

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21
Q

retrograde transport

A

substance move from axon terminal towards the cell body

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22
Q

what releases neurotransmitters

A

axon terminal or terminal boutines

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23
Q

the cell body of a neuron is never

A

mylenated

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24
Q

multipolar neurons

A

3 or more processes

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25
bipolar nuerons
2 processes
26
unipolar neurons
1 process
27
3 types of neurons based on function
1. sensory or afferent neurons 2. motor or efferent neurons 3. interneurons or association neurons- found between motor and sensory
28
trigger zone
nerve impulses generated at area
29
rarest type of neuron in human body
bipolar
30
all bipolar neurons are
sensory neurons (some special sensory)
31
most unipolar neurons are
sensory neurons
32
postsynaptic neuron
neuron carrying impulse away from synapse (can be an effector cell)
33
chemical synapses are released into the ____ while electrical synapses are sent directly to the adjacent cell via ____
synaptic cleft, gap junctions
34
synaptic cleft is filled with
interstitial fluis, so action potential can't babe conducted
35
which synapse type is faster
electrical because chemical synapses have to be changed into electrical
36
post synaptic neurons contain
ligand gated receptors to which the neurotransmitter binds
37
nerve impulse depolarization causes`
voltage gated CA2 channels to open
38
3 ways neurotransmitters are removed from postsynaptic receptors
degradation by enzymes, reuptake by astrocytes or presynaptic terminal, diffusion away from synapse
39
6 types of neuroglia (4 CNS, 2 PNS)
1. astrocyte 2. microglia cell 3. ependymal cells 4. oligodendrocyte 5. schwann cells 6. satellite cells
40
which cells produce myelin
oligodendrocytes and schwann cells
41
intranodal segment
oligodendrocytes produce one sheet of myelin for multiple neurons`
42
predominant glial cells are found in
white matter
43
oligodendrocyte histology
unstained cytoplasm and dark nucleus. usually in rows
44
largest nueroglia
astrocyte
45
astrocytes are found in
white matter and grey matter
46
major function of astrocytes
controlling the ionic environment of neurons | other: get rid of excess neurotransmitters, form cellular scar tissue, assist in CNS embryo development
47
perivascular feet
part of astrocyte that cover capillary endothelia cells and contribute to the blood brain barrier
48
ependymal cells
low columnar or cuboidal. line spaces found in brain and spinal cord.
49
ependymal cells have
cilia that extends into places with cerebral spinal fluid; helps CSF move
50
ependymal cells are modified in
the ventricles to become the choroid plexus
51
cells that line the central canal
ependymal cells
52
microglia are distributed in
white and grey matter evenly
53
microglia histology
short irregular processes with spikes, nuclei are elongated
54
major function of microglia
analyze cells for damaged tissues ; major mechanism for immune defense
55
neuroglia that can migrate
microglia
56
neuroglia that originates form blood monocytes
microglia
57
what morphology do microglia assume when activated
macrophages; become phagocytotic and antigen presenting
58
satellite cell
create covering layer over neuronal bodies in the PNS ganglia
59
white matter is composed of primarily ____ while gray matter is composed of ____
myelinated axons with some neuroglia, unmylennated axons with nissl bodies
60
myelinated fibers conduct impulses ____ while unmyelinated fibers conduct _____
rapidly, slowly
61
continuous conduction
ummylenated axons
62
saltatory conduction
mylenated axons
63
action potential has to be regenerated at
nodes of ranvier