Neural tube defects Flashcards
(4 cards)
1
Q
Definition of neural tube defects
A
Congenital abnormalities that result from the premature closure of the neural tube within 28 days of conception e.g., spina bifida, anencephaly, and encephalocele
2
Q
Risk factors for neural tube defects
A
Folate deficiency
Maternal B12 deficiency
History of having an infant with a neural tube defect
Smoking
Diabetes
Obesity
Use of antiepileptic drugs
3
Q
Which patients groups should have high-dose folic acid (5mg) during pregnancy?
A
Women with diabetes, sickle-cell disease, and on antiepileptics
4
Q
When should 4000mcg folic acid be taken in pregnancy?
A
All pregnancies up until 12 weeks.
