Neuraxial Lecture 3 (Exam 1) Flashcards

(26 cards)

1
Q

Isobaric solution has a baracity of:

A

1 (Same as CSF)

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2
Q

The density of a LA solution compared to the CSF

A

Baracity

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3
Q

Hyperbaric solution has a baracity of:

A

> 1 - sinks and moves downward from the point of injection

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4
Q

Hypobaric solution has a baracity of :

A

< 1 - moves upwards and rises from the point of injection

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5
Q

Isobaric Bupivicaine dose

A

0.5% or 0.75% in saline

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6
Q

Isobaric Lidocaine dose

A

2% in saline

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7
Q

Isobaric Tetracaine dose

A

0.5% in saline

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8
Q

Hypobaric bupivicaine dose

A

0.3% in water

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9
Q

Hypobaric Lidocaine dose

A

0.5% in water

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10
Q

Hypobaric tetracaine dose

A

0.2% in water

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11
Q

Hyperbaric bupivicaine dose

A

0.75% in 8.25% dextrose

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12
Q

Hyperbaric lidocaine dose

A

5% in 7.5% dextrose

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13
Q

Hyperbaric tetracaine dose

A

0.5% in 5% dextrose

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14
Q

Hyperbaric procaine dose

A

10% in water

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15
Q

What is the lowest possible level the hyperbaric LA will travel during SAB procedure? (injected at around L4-5)

A

T6-S2

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16
Q

The spinal cord uptake of the LA is possible due to the _______ nature of the LA

A

lipid-soluble

17
Q

Spread of LA occurs in a ______ and _____ direction from the site of injection simultaneously

A

cephalad and caudad

18
Q

Does metabolism of the LA take place in the CSF?

19
Q

How are LA eliminated?

A

LA are eliminated via reuptake (vessels in the pia mater)

20
Q

______ drugs have slow reuptake because they have a hihg affinity for epidural fat

A

Lipophilic (Bupivicaine has a longer duration than lidocaine)

21
Q

During which procedure are you always aspirate before injection?

22
Q

Epidurals have an onset time of about:

A

10-25 minutes

23
Q

When dosing epidurals, we should dose _______ with ___ mL to avoid: (3)

A

Dose intermittently with 5 mL to avoid:
Accidental High spinal
Hypotension from rapid autonomic blockade
LAST

24
Q

Re-dose epidurals when you have dropped sensory blockade to ___ segments below baseline block

A

2 segments below
(If original block was at T4, and now its only at T6, you can re-dose)

25
What drug has the fastest onset of all LA even though its pKA is not the closest to the physiologic pH?
2-Chloroprocaine (d/t high concentration)
26
2-Chloroprocaine is commonly used in ______ anesthesia and metabolized by ________ Redose every: _____ min
OB anesthesia Metabolism: Plasma cholinesterase Redose q 45 min