Neuro 1 Flashcards
(64 cards)
What is Akinetic Mutism?
Unresponsiveness to the environment, makes no movement, but sometimes opens eyes.
What is a Persistent Vegetative State?
Devoid of cognitive function, but has sleep-wake cycles
Usually from severe brain damage, comes with end of life decisions
What is Locked In Syndrome?
Inability to move or respond except eye movements due to a lesion affecting the pons
What is meant by Altered Level of Consciousness?
When a patient is not oriented, doesn’t follow commands, or needs persistent stimuli to achieve a state of alertness
The patient with an altered LOC is at risk for alterations in every body system
What is the Glasgow Coma Scale?
What is Decorticate Posturing?
Posturing and flexion of the upper extremities, internal rotation of the lower extremities, and plantar flexion of the feet.
Results from neurologic injury
What is Decerebrate Posturing?
Extension and outward rotation of upper extremities and plantar flexion of the feet
Results from neurologic injury
What would inhibit an accurate motor response assessment?
If the patient was taking neuromuscular-blocking agents or paralytics
What is the most common diagnostic testing for a suspected neurological injury?
Computed Tomography
CT
Which labs may be diagnostic for neurological injury?
- Blood glucose
- Serum electrolytes
- Serum ammonia (hepatic encephalopathy)
- Serum BUN
- Serum Osmolality
- Calcium Levels
- PT/PTT
- Serum Ketones (DKA?)
- ETOH/BAC
- Drug concentrations
- Arterial Blood Gases
What is Delirium?
ACUTE CONFUSION STATE
- Begins with disorientation, can progress to changes in LOC, irreversible brain damage, and death
- Happens to 80% of ICU patients
- Can be mistaken for dementia
- Need to assess closely with CAM (Confusion Assessment Method)
What are the risk factors for Delirium?
- Use of benzodiazepines
- Blood transfusions
- Age
- Dementia
- Prior coma
- Recent emergency or trauma
- Older adults with polypharmacy
What is Dementia?
GRADUAL PROGRESSIVE CONFUSION
- Progression can take months or years
- Cause: neurodegeneration
Some cases can be reversible IF the cause is a pathologic condition masquerading as dementia
What is the most common type of Dementia?
Alzheimer’s Disease
Up to 75% of dementia cases
Other types: Vascular, Neoplastic, Demyelinating, infectious, inflammatory, toxic, metabolic, psychiatric
What is a Seizure?
- Abnormal electrical discharges in the cerebral cortex
- Manifests as an alteration in sensation, behavior, movement, perception, or consciousness
What is Epilepsy?
A group of syndromes characterized by more than one unprovoked seizure
What is a Focal Onset Seizure?
- Electrical activity begins on one side or “focus” of your brain.
- Symptoms usually affect one side of your body and may or may not affect your awareness
- May or may not remember the seizure
What is a Generalized Onset Seizure?
- Affect both hemispheres of your brain
- Symptoms affect both sides of your body
- Usually more severe
What are some specific causes of seizures?
- Cerebrovascular Disease
- Hypoxemia
- Fever (in children)
- Head Injury
- Hypertension
- Central Nervous System Infections (e.g. meningitis)
- Metabolic and toxic conditions
- Brain tumor
- Drug and alcohol withdrawal
- Allergies
What is Status Epilepticus?
Acute prolonged seizure activity
- Lasts 5 minutes or longer
- Serial seizures occurring without full recovery of consciousness between attacks
- Also describes a seizure without impairment of consciousness lasting 30 minutes or longer
- Produces cumulative effects
- Vigorous muscular involvement causes heavy metabolic demand
- Can lead to brain anoxia and respiratory arrest
- Medical emergency
What can cause Status Epilepticus?
- Interruption in anticonvulsant therapy
- Fever
- Concurrent infection
- Illness
What is a Stroke?
- Sudden loss of function resulting from a disruption of the blood supply to part of the brain
- Types: Ischemic and Hemorrhagic
The leading cause of long term disability in the US and 5th leading cause of death
What is a Transient Ischemic Attack (TIA)?
- Temporary neurologic deficit resulting from a temporary impairment of blood flow
- A warning sign of an impending stroke!
What are the modifiable risk factors for Stroke & TIA?
- Hypertension (primary risk factor)
- Cardiovascular disease
- Elevated cholesterol
- Elevated hematocrit
- Obesity
- Diabetes
- Oral Contraceptive use
- Smoking, drug, alcohol abuse