Neuro 1.1 Flashcards

1
Q

Possible symptoms of Neuro problems

A
  • decreased vision
  • pain
  • headaches
  • diplopia
  • ocular motility problems
  • nystagmus (spontaneous eye movements)
  • pupillary abnormalities
  • lid/facial abnormalities
  • transient visual loss
  • illusions/hallucinations
  • micropsia (objects appear smaller)
  • macropsia (objects appear bigger)
  • dyschromatopsia (loss of colour perc)
  • metamorphopsia (straight line grid appears wavy)
  • visual agnosia (difficult to recognise visually presented objects)
  • ataxia (loss of bodily movements)
  • hemiparesis (weakness of one side of body)
  • hemisensory weakness (loss of sensation on one side of body)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

H&S of Reduced Vision

A
  • associated symptoms (pain, headache etc)
  • unilateral/bilateral
  • time course
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Reduced vision - unilateral or bilateral

A
  • unilateral - lesion anterior to chiasm
  • bilateral - either bilateral ON’s or retina/chiasmal/retrochiasmal disease
  • homonymous hemianopia - often regarded by px’s as affecting one eye instead of one side of vision
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Reduced vision - time course

A
  • minutes - ischaemic retinal cause
  • hrs - most commonly ischaemic, more likely ON
  • days/weeks - more commonly inflammation
  • months/years - compressive
  • can be overlap
  • px’s can become suddenly aware of chronic problem when fellow eye is covered
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Examination of Neuro cases

A
  • VA
  • pupils
  • fundus examination
  • VF
  • CV
  • contrast sensitivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pupillary testing - sympathetic branch

A
  • sympathetic innervation - innervates dilator pupillae muscle
  • causes pupil dilation
  • has much longer course than parasympathetic branch
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pupillary testing - parasympathetic branch

A
  • parasympathetic innervation - innervates pupil sphincter muscle
  • causes pupil constriction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pupillary testing method

A
  1. Observe size, shape and asymmetry of pupils
  2. Check for D+C responses
  3. Swinging flashlight test (check for RAPD)
  4. Check for near reflex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pupillary testing - Step 1 (size, shape)

A
  • use a distant non-accommodative target of light in dim light
  • check for Anisocoria
    • Difference of >0.4mm is anisocoria
    • 25% of normal px’s have this in dim light, 10% in room light
    • If anisocoria present, measure pupil sizes in dim and bright light and check difference (RE-LE)
  • difference constant - normal
  • difference largest in dim light - possible problem with dilation of smaller pupil
  • difference largest in bright light - possibly problem with constriction of larger pupil
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pupillary testing - Step 2 (D+C responses)

A
  • can get no response or sluggish response
  • magnitude of responses correlated to degree of damage (sluggish - minor, no response - severe)
  • direct reflex affected - problem anywhere in nerve pathway
  • direct reflex reduced but not absent - problem anywhere in nerve pathway
  • No direct reflex in one eye and no consensual reflex in the other eye - likely to be problem inside eye/affecting nerve of eye in which the direct response affected
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pupillary testing - Step 3 (swinging flashlight)

A
  • check for RAPD!
  • Pupil stays constricted (normal) = no RAPD
  • Pupils dilate fully = total RAPD
  • Pupils dilate a little bit and slowly; sluggish response = partial RAPD
  • Magnitude of responses correlated to degree of damage (sluggish - minor, full dilation - severe)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

RAPD

A
  • Gross retinal abnormality (VA of 6/60 or worse) in one eye or asymmetric
  • Impaired ON function
  • Asymmetric chiasmal compression (location affects one eye more than the other)
  • May be detected even if pupillary response in 1 eye can’t be evaluated – trauma, pharmacologic
  • RAPD does not result in anisocoria, are two separate things
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pupillary testing - Step 4 (near reflex)

A
  • usually only needed if abnormality in above steps
  • look at distant, non-accommodative target
  • look at near, accommodative target
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

VF testing

A
  • supplements acuity in assessing visual loss
  • helps localise lesion along afferent visual pathway
  • quantifies defect and assesses change over time
  • choice of field testing, will depend on:
    • degree of detail required
    • px’s ability to co-operate
  • Confrontational, Amsler, Perimetry
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

VF Lesions

A
  • RNFL
    • respect horizontal midline
    • one eye only or difference between eyes
  • ON
    • one eye only
  • Optic Chiasm
    • bitemporal hemianopia (central chiasm)
    • binasal hemianopia (lateral chiasm)
  • LGN
    • inferior and superior fibres 1st meet
  • Optic Radiations
    • fan out, sweeping around lateral ventricle to occipital lobe
    • inferior fibres -> temporal lobe
    • superior fibres -> parietal lobe
  • R field  L retina, L brain
  • L field  R retina, R brian
  • Primary Visual Cortex
    • Disproportionately large area is macular function
  • Post Chiasmal Lesions
    • Affects BE
    • Respect vertical midline
    • More posterior produces:
      • Congruous (same between eyes)
      • Homonymous (same part of field in BE)
      • Macular sparing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Colour Vision

A
  • Optic neuropathies manifest red-green defects
  • Red desaturation - bright red would look more like a ‘maroon’
  • ON affected - dyschromatopsia > VA loss
  • Macula affected - dyschromatopsia = VA loss
  • Dyschromatopsia - inability to normally perceive colours
  • CV defects can often persist even after recovery of VA
17
Q

Contrast Sensitivity

A
  • VA is tested at a high level of contrast
  • Contrast sensitivity more sensitive
  • Grating tests – Vistech
    • Difficulty to administer and reliably reproduce
  • Pelli-Robson
    • Single size optotype with gradually diminishing contrast level
  • Useful in detection and quantitation of visual loss in presence of normal VA
18
Q

Optic Neuropathy

A
  • neuropathy - disease or dysfunction of one or more of the peripheral nerves
  • damage to the ON due to any cause
  • both swelling and atrophy give signs of optic neuropathy
19
Q

Optic Atrophy

A
  • atrophy - wasting away of the ON
  • generally causes pale coloured nerve
20
Q

Optic Oedema

A
  • swelling of the ON
21
Q

Optic Neuritis

A
  • ‘itis’ - inflammation
  • Kanski - “inflammation, infection or demyelinating process of the ON”
  • Retrobulbar neuritis - inflammation behind the ONH