Neuro Flashcards

(64 cards)

1
Q

what is acute colonic pseudoobstruction?

A

Autonomic disruption of the colon causes painful abdominal distension, the inability to poop, and vomiting

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2
Q

what causes acute colonic psuedoobstruction

A
  1. electrolyte imbalances
  2. trauma, recent surgery, infections
  3. medications
  4. Neurological disorders
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3
Q

imaging for acute colonic psuedoobstruction shows what

A

X-Ray will show colonic dilation, normal haustra, and a non dilated small bowel

CT scan will sow colonic dilation and NO anatomic obstruction

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4
Q

what are the symptoms of acute colonic pseduoobstruction

A

abdominal distension, vomiting, inability to poop, decreased bowel sounds, tympanic to percussion

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5
Q

complications of acute colonic psuedoobstruction

A

bowel perforation (gaurding, rigidity, reboudn tenderness)

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6
Q

management of acute colonic psuedoobstruction

A

NPO (bowel rest), nasogastric decompression and IV neostigmine if there is no improvement within 2 days

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7
Q

after an MI what interventions are aimed at achieving the most improvement for a patient’s long term prognosis?

A

time it takes to restore coronary blood flow - this will limit myocardial damage and improve cardiovascular mortality

*this is done by PCI or fibrinolysis

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8
Q

SIADH serum osmolality and urine osmolality levels

A

serum <275 mOsm/kg H20

urine <100 mOsm/kg H20

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9
Q

a patient with a hilar mass in the setting of weight loss, cough, and a significant smoking history is concerning for?

A

small cell lung cancer

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10
Q

small cell lung cancers can cause what paraneoplastic syndrome

A

SIADH

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11
Q

types of SIADH

A

mild hyponatremia: nausea and forgetfulness
severe hyponatremia: seizures and coma
Euvolemia: most mucus membranes, no edema

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12
Q

managemtn of SIADH

A

fluid restriction with salt tablets

for severe Na<120 - hypertonic saline

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13
Q

when adminsitering hypertonic saline you want to correct the sodium levels slowly with a rate of <8 mEq/L over the first 24 hours to prevent what complication

A

osmotic demyelination syndrome

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14
Q

what are the two most important risk factors for stroke on USMLE

A

hypertension and AFIB

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15
Q

ACA stroke signs

A

motor and sensory abnormalities of the contralateral leg

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16
Q

MCA stroke signs

A

motor and sensory abnormalities of the contralteral arm and face

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17
Q

dominant MCA strokes are usually on which side

A

left sided

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18
Q

dominant MCA stroke can lead to?

A

Wernicke or Broca Aphasia

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19
Q

nondominant MCA stroke can cause?

A

hemispatial neglect

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20
Q

what is hemispatial neglect

A

the inability to draw clockface

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21
Q

PCA stroke signs

A

prospagnosia ( inability to recognize faces)

contralateral homonymous hemianopsia with macular sparing

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22
Q

lateral medullary syndrome is caused by?

A

posterior inferior cerebellar artery (PICA) or vertebral artery ischemia

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23
Q

lateral medullary syndrome is also known as?

A

wallenberg syndrome

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24
Q

what are the symptoms of lateral medullary syndrome

A

dysphagia and ipsilateral horner syndrome

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25
what is horner syndrome
ipsilateral miosis, partial ptosis, and anhidrosis
26
horner syndrome can be caused by what two things?
pancoast tumor, or lateral medullary syndrome
27
what is the artery involved in medial medullary syndrome
anterior spinal artery
28
what are the signs of medial medullary syndrome
ipsilateral tongue deviation
29
what is the artery involved in lateral pontine syndrome
anterior inferior cerebellar artery (AICA)
30
signs of lateral pontine syndrome
ipsilateral Bells Palsy (facial droop, ptosis)- cranial nerve 7
31
weber syndrome is a stroke in what location
the midbrain
32
what are the symtoms of weber syndrome
ipsilateral CN III palsy (down and out eye) with contralateral spastic hemiparesis (weakness)
33
locked in syndrome is a stroke of what artery
Basilar artery
34
signs of locked in syndrome
inability to move enitre body expect for the eyes
35
gerstmann syndrome is a stroke of?
the angular gyrus of the parietal lobe
36
what is the tetrad of syndrome from gerstmann syndrome
1. agraphia (inability to write) 2. acalculia (inability to do math) 3. finger agnosia (cant identify fingers) 4. left-right dissociation (cannot differentiate between left and right sides of the body)
37
Hemiballismus is a stroke of what location?
subthalamic nucleus
38
signs of a hemiballistic stroke
ballistic flailing of contralateral arm or leg
39
what is the mechanism of lacular infarcts?
hypertension causes liphyalinosis which is atheromas in the small lenticulostriate (deep) arteries in the brain this plaques cause ischemia in the brain which can lead to necrosis and reabsorption of tissue and forms tiny cavities called lacunae
40
symptoms of a lacunar infarct
specific syndromes based on their location pure motor hemiparesis, purse sensory stroke, ataxic hemmiparesis
41
cortical stroke symptoms
aphasia, neglect, visual field losses
42
what is wenicke aphasia
fluent aphasia where the patient can speak with a normal pace and use lots of words but it doesnt make any sense "WORD SALAD" comprehension is impaired, repition is impaired
43
where is wernickes area located what causes it
temporal lobe; caused by a L sided MCA infarct
44
what is brocas aphasia
non-fluent aphasia there is frustration in not being able to make sense comprehension is NORMAL repetition is impaired
45
brocas area is located where and caused by what infarct
frontal lobe caused by a L sided MCA infarct
46
Conductive aphasia
stroke of the arcuate fasciulus which connects wernicke and brocas areas repetition is impaired only
47
global aphapsia
bascially brocas, acrcuate fasciculus and wenickes at the same time no repetition, no comprehension, no word salad
48
transcortical sensory aphasia
same presentation as wernicke but repeittion is intact
49
transcorticol motor apahsia
same presentation as broca but repeptition intact
50
what imaging is done to look for a stroke
non-contrast CT
51
how does blood appear on a non contrast CT
hyperdense (bright)
52
for an ischemic stoke what is given if symptom onsent has been within the past 4.5 hours ?
tPA (tissue plasminogin)
53
what does the 4.5 hour window refer to
when the patient was last observed as normal
54
if the 4.5 hour window has elapsed what do you do for an ischemia stroke
give aspirin
55
ischemia strokes bp should be rapidly be broght down below the threshold of what? After meeting this threshold slower blood pressure control is done. AN increase in blood pressure can actually help perfusion of penumbric areas on ischemia
185/110
56
what is the treatment of a hemorrhagic stroke (hyperdense CT)
do NOT give tpa 1. lower the blood pressure rapidly so that systolic is less than 140mmhg 2. reverse anticoagulation if the patient is on it (FFP for patients on warfarin)
57
correction of hypernatremia too quickly with hypotonic aline can cause
cerebral edema
58
correcting hyponatemia too quickly with hypertonic saline can cause
central pontine myelinolysis aka osmotic demyelination causes locked in syndrome
59
what is a hypercalcemic crisis
a deliruium like state caused by SEVERE hypercalcemia usually caused by malignancy or primary hyperparathyroidism
60
treatment of hypercalcemia
normal saline bisphophonates
61
what is psuedotumor cerebri
increased intracranial pressure with no structural cause causes: obesity, idopathic intracranial hypertension, OCP, isotretinonin, danazol
62
reye syndrome
cerebral edema and hepatotoxicity from giving aspirin to children during a viral infection
63
diffuse aconal injury
acceletation, deceleration, contact brain injury that causes axonal shearing and tearing and subsequent brain swelling can have severe cognitive defects, motor or sensory dysfunction
64