Neuro and Anesthetics Flashcards

(63 cards)

1
Q

What is a seizure?

A

hyper excited neurons called a focus

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2
Q

how many sides of the brain is a focal onset seizure?

A

on hemisphere

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3
Q

Generalized onset seizures use what sides of the brain?

A

both sides

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4
Q

Goal of seizure tx?

A

allow pt to live a near normal or normal life

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5
Q

All seizure meds carry a risk of causing what?

A

suicide

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6
Q

Phenytoin Loading Dose?

A

15mg/kg

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7
Q

Mx dose of Phenytonin

A

300-400mg qd

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8
Q

Phenytoin is the drug of choice for what?

A

Emergencies, status epilepticus

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9
Q

Do not use Phenytoin if pat has what?

A

2nd or 3rd heart block, bradycardia or SA block

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10
Q

What people may have tog et genetic testing because of mutation before using Phytnoin?

A

Asian

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11
Q

Carbamazepine is also called what?

A

Tegretol

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12
Q

What is Tegterol used for besides seizures?

A

Bi Polar, and trigeminal neuralgia

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13
Q

What lab do you what to get a baseline of when giving Tegretol?

A

CBC

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14
Q

What is a common side effect of Tegretol?

A

Tinnitus

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15
Q

What should patients not drink when taking Tegretol?

A

Grapefruit Juice

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16
Q

Valporate is also called what?

A

Depakote

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17
Q

Depakote dose?

A

500mg-1g daily

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18
Q

Do not give Depakote if someone has what?

A

liver condition

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19
Q

What is a black box warning for Depakote?

A

Hepatotoxicity

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20
Q

If patient is taking Depokote and Topiramate what should you assess for?

A

Hyperammonemia

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21
Q

Oxycarbazepine daily dose?

A

300mg-600mg

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22
Q

MOA of ocyarbazepine?

A

Blocks sodium channels

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23
Q

Keppra Dose?

A

500mg BID

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24
Q

What is the off label use for Keppra?

A

TBI, subarachnoid hemorrhage, and status epileptics

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25
What is a rare adverse effect Keppra can cause?
Neuropsychiatric sx
26
Gabapentin common SE?
dizziness, fatigue, peripheral edema
27
Baclofen dose?
15-20mg po bid/tid
28
What to avoid with Baclofen?
alcohol and other CNS depressantas
29
What can abrupt withdraw of this med cause?
seizures
30
What drug is used to CP, malignant hyperthermia and spasticity?
Dantrolene
31
Where does Dantrolene work?
the level of the muscle
32
What can dantrolene cause?
Muscle Atrophy
33
What is a serious SE of Dantrolene?
Hepatotoxicity
34
Common SE of Dantrolene?
muscle weaknessm N/V, drowsiness
35
Flexeril dose?
10mg TID
36
Serious SE of Flexeril?
Cardiac rhythm disturbances
37
What drugs should you not use with Flexeril and why?
MAOI because could cause serotonin syndrome
38
Is Flexeril centrally acting?
Yes
39
Sx of Serotonin Syndrome?
Tachy, Sweating, NVD, Fever CNS, ANS, Neuromuscular, GI
40
Robin dose?
1000mg QID
41
Rate to push IV Robin?
3mL/min
42
What should you have patient do after giving Robin?
Have them laying on side for 10-15 min post administration
43
Education to patients that are taking Robin?
May turn urine green, brown, black
44
Valium dose?
2-10mg TID/QID
45
What vS do you want to monitor the most when giving Valium?
Respiratory rate
46
What is the MOA of Valium?
Makes GABBA activate at spinal cord
47
What happens if you stop taking Valium quick?
Withdraw Sx
48
MOA of local Anesthetics?
Blocks Na+ channel in the axonal membrane stoping Na from entry, stoping activity of neurons.
49
Can kids under 2 get Benzocain and why or why not?
No because it can turn them blue with the methemoglobin.
50
What do you want to monitor when giving someone local anesthetics?
VS, EKG, use least amount needed, and look for allergic reactions
51
Ester is used for what?
Local anesthesia and pain suppression
52
What delays absorption of Novocain Ester type?
Epinephrine
53
Adverse effect of Novocaine Ester type?
Allergic reaction are very significant
54
If a patient is allergic to what they should be considered allergic to all Ester anesthetics?
Procaine
55
Novocaine is also called what?
Procaine
56
What is an amide type anesthetic?
Lidocaine
57
Adverse Effects of Lidocaine?
CNS effects, Cardio effects, and low risk to allergic reactions
58
Serious AE to Lidocaine amide type anesthetic?
Cardiovascular toxicity
59
What is Xylocaine?
Brand name of Lidocaine
60
Lidocaine with Eli does what?
decreases blood flow by vasoconstriction delaying systemic absorption of anesthetic
61
Why add Eli?
Reduces the potential for systemic toxicity
62
Appy how much topical anesthetic?
smallest amount needed
63
Avoid application of topical anesthetic to what?
Large areas, broken or irritated skin, heating site and strenuous exercise, or wrapping area