Neuro Review Table - Onc

Question 1

Schwannoma

Answer 1

palisading arrangement (Verocay bodies), S100 positive, NF2 (bilateral)

Question 2

epidermoid cyst

Answer 2

T1 iso-hypo, T2 hyper, diffusion restricted, CP angle

Question 3

dermoid cyst

Answer 3

T1 hyper, T2 variable, midline, hair follicles

Question 4

neurocytoma

Answer 4

intraventricular, looks like oligo but has +synaptophysin

Question 5

arachnoid cyst

Answer 5

T2 hyper, no diffusion restriction, temporal lobe

Question 6

colloid cyst

Answer 6

T1 iso-hyper, T2 hypo, 3d ventricle

Question 7

medulloblastoma

Answer 7

PNET, common in boys, cerebellar location, Homer-Wright rosettes

Question 8

DNET

Answer 8

float cells

Question 9

Craniopharyngioma

Answer 9

bimodal age, Rathke pouch rests, benign, appear like thyroid tissue

Question 10

choroid plexus papilloma

Answer 10

WHO Grade I. finger like extensions with stroma.

Question 11

Rathke pouch cyst

Answer 11

between anterior and posterior pituitary

Question 12

Neuroblastoma

Answer 12

children, opsoclonus myoclonus

Question 13

cavernous hemangioma

Answer 13

aka. cavernous malformation.
Dilated thin-walled VEINS - thick, hyalinized walls
One layer of endothelium + NO INTERVENING brain
“popcorn” appearance on MRI (blood of different ages)
Associated with KRIT1 mutations (AD)

Question 14

developmental venous anomaly

Answer 14

aka DVA and “venous angioma”;
most common cerebral vascular malformation
Thickened venous channels separated by normal brain
Felt to be 2/2 “arrested development” of venous structures
Caput medusae sign on imaging.