Neuroanatomy Flashcards

1
Q

Ganglia

A

Groups of neurons

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2
Q

dorsal roots

A

carry information from body to spinal cord

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3
Q

ventral roots

A

carry outgoing motor axons

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4
Q

perikaryon

A

cell body of a neuron

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5
Q

schwann cells

A

type of glial cell that surrounds neurons, keeping them alive and sometimes covering them with a myelin sheath, and are the major glial cell type in the peripheral nervous system

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6
Q

node of ranvier

A

periodic gap in the insulating sheath (myelin) on the axon of certain neurons that serves to facilitate the rapid conduction of nerve impulses

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7
Q

neuroglia

A

Neuronal supporting cells, non-conducting nervous system cells, provide mechanical support to neurons, insulate and prevent neural impulses from spreading in unwanted directions

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8
Q

Glutamate

A

Main excitatory neurotransmitter, stimulating neurons to fire commands, brain uses glutamate to build pathways between neurons that reinforce your memory and help you learn

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9
Q

GABA

A

main inhibitory neurotransmitter, reduces activity in the CNS and blocks certain brain signals
Produces a calming effect that slows you down

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10
Q

Dopamine

A

Floods synapse between neurons when something rewarding happens, brings feelings of pleasure, Helps with wakefulness, releasing insulin, creating voluntary muscle movement

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11
Q

Adrenaline (epinephrine)

A

responsible for fight or flight response
Produced by adrenal glands located above kidneys

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12
Q

Serotonin

A

influence over mood, promoting feelings of well-being and happiness, makes you feel full/nauseous

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13
Q

Oxytocin

A

love hormone, made in hypothalamus and released via pituitary gland, crucial for social and physical health

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14
Q

Acetycholine

A

directly affects muscles, woks at neuromuscular junction, released to muscle fibers to trigger action potential and makes muscle contract, helps with memory and learning

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15
Q

Diaencephalon

A

caudal (posterior) part of the forebrain, contains the ephithalamus, thalamus, ventral thalamus, and third ventricle

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16
Q

Meninges

A

3 layers protecting the brain, includes the dura matter, arachnoid membrane, and pia matter

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17
Q

Dura matter

A

Outer-most layer of three layers protecting the brain, tough

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18
Q

Arachnoid membrane

A

next to dura matter, middle layer

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19
Q

Subdural space

A

in between dura matter and arachnoid membrane

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20
Q

Subarachnoid space

A

in between arachnoid membrane and pia membrane, filled with CSF and blood vessels

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21
Q

Pia matter

A

membrane covering the brain

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22
Q

Forebrain

A

cerebrum

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23
Q

Midbrain

A

topmost part of the brainstem, the connection central between the brain and the spinal cord

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24
Q

Hindbrain

A

lower part of the brainstem, comprising the cerebellum, pons, and medulla oblongata

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25
Q

3 nuclei of cerebral hemispheres

A

Basal ganglia, hippocampal formation, amygdala

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26
Q

agenesis

A

born without corpus callosum

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27
Q

inability to see faces would be caused by damage to

A

right hemisphere, fusiform region

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28
Q

acalculia (spatial type) would be caused by damage to

A

right hemisphere

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29
Q

subtle language deficits in prosody, articulation, and use of abstract constructs would be caused by damage to

A

right hemisphere

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30
Q

area of the brain that helps us understand intended meaning of vocalizations

A

right hemisphere

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31
Q

Lissencephaly

A

genetic malformation characterized by absence of folds in cortex

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32
Q

Polymicrogyria

A

abnormal brain development before birth

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33
Q

Topamax

A

antiepileptic med prescribed for seizures, cognitively blunting at high doses (impacts WM and verbal fluency)

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34
Q

Frontal lobe lesions impair

A

decision-making, difficulty with probability, Acute eye deviation with persistent neglect, contralateral hemiplegia (body paralysis), and anosmia (either total or partial loss of smell)

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35
Q

Lesions to right frontal/parietal lobes cause

A

Neglect (failure to respond/report, orient to novel stimuli)

36
Q

Temporal legions cause

A

Contralateral superior quadranopia (field deficit in the superior field of both eyes on the same side) = “pie in the sky”

37
Q

Parietal lesions would likely cause

A

Lesions cause difficulty with tactile perception/discriminations by touch

38
Q

Occipital lesions

A

Lesions cause bilateral hemianopia (cortical blindness), hallucinations, color agnosia, agraphia

39
Q

Frontal lobe

A

Associated with intellectual functions, reasoning, aggression, sexual bx, speech, smell, and voluntary movements

40
Q

Orbital frontal lobe

A

involved in response initiation and inhibition

41
Q

Dorsolateral prefrontal cortex

A

important for sequencing, persistence, and switching

42
Q

Broca’s area

A

located in frontal cortex, above and behind left eye, involved in language processing, speech production, and comprehension, put thoughts into words, premotor area for speech sounds

43
Q

Temporal lobe

A

associated with emotion, interpretation of language, hearing, and memory

44
Q

Heschel’s gyrus (transverse temporal gyrus)

A

located in temporal lobe, associated with primary auditory cortex, sort auditory stimulation for direction, pitch, loudness, and other acoustic properties rather than words

45
Q

Broadman areas

A

cytoarchitectural areas of the neocortex, regions with similar cell structure

46
Q

Wernicke’s area

A

located in the posterior segment of the superior temporal gyrus in dominant hemisphere, associated with comprehension of speech sounds, considered the receptive language center of the brain

47
Q

Parietal lobe

A

associated with body sensory awareness, language, abstract thought (specifically math), and body imaging, analysis of motion and spatial relationships

48
Q

Posner and Peterson’s model of attention

A

in parietal lobe, posterior attention system is responsible for orienting and awareness of environment and anterior attention system is associated with signal detection

49
Q

Occipital lobe

A

associated with receiving, interpreting, discriminating visual stimuli, and visual stimuli memory

50
Q

Calcarine fissure

A

primary visual area

51
Q

Dorsal pathway

A

involved with visual perception of where objects are located

52
Q

Ventral pathway

A

involved with visual analysis of what objects are

53
Q

Basal ganglia

A

help brain control body movements, role in movement, decision-making, and reward/addiction

54
Q

6 parts of basal ganglia

A

caudate nucleus, globus pallidus, putamen, substantia nigra, subthalamic nucleus, ventral pallidum

55
Q

Caudate nucleus

A

pair of brain structures controlling high-level fx including planning, movement, learning, memory, reward, motivation, emotion, and romantic exchanges (oxytocin)
Dysfx - associated with dementia, ADHD, bipolar, Huntington’s, Parkinson’s, Autism, Tourette’s, OCD

56
Q

Substantia nigra

A

produces dopamine, controls movement and muscle tone, has two sections (pars reticulata and pars compacta)

57
Q

Pars reticulata

A

movement of eyes, ability to learn and think, GABA to stop signals going to muscles

58
Q

Pars compacta

A

secrete dopamine, involved emotions, learning, judging risk/reward, motivation

59
Q

Hippocampal formation

A

anterior to amygdala + posterior to corpus callosum, major part of limbic system, lie along longitudinal axis of the brain, form floor and part of the medial wall of interiors hors of the lateral ventricle, best known for learning and memory, three main parts:
Hippocampus (Ammon’s horn), Dentate gyrus, and Subiculum

60
Q

Amygdala

A

associated with fear, aggression, learning through rewards/punishment, implicit (unconscious) memory, social communication and understanding, emotions related to parenting and caregiving, emotions connected to memories, learning, and addiction

61
Q

Internal capsule

A

a two-way tract for the transmission of information to and from the cerebral cortex, posterior to the basal ganglia

62
Q

Primary motor cortex

A

controls voluntary movements and limbs and trunk, contains neurons projecting directly to spinal cord to activate somatic motor neurons

63
Q

Primary sensory areas

A

receives information from peripheral receptors with only a few synaptic relays interposed (less stops along the way)

64
Q

4 principles of anatomical organization

A

1) each system contains relay centers 2) each system is composed of several distinct pathways
3) each pathway is topographically organized 4) most pathways cross the body’s midline

65
Q

Topographic organization

A

the projection of adjacent neurons in one area to adjacent neurons in another

66
Q

Diencephalon

A

thalamus and hypothalamus taken together

67
Q

Thalamus

A

relay center, processes and distributes almost all sensory and motor info going to the cerebral cortex

68
Q

lateral geniculate gyrus

A

part of thalamic nuclei which is part of visual pathway
Lesion may cause left homonymous visual field deficits

69
Q

Hypothalamus

A

under the thalamus, responsible for regulations of the ANS, homeostasis, controls body temperature, thirst, hunger, and emotional bx

70
Q

Suprachiasmatic nucleus

A

bilateral structure located in the anterior part of the hypothalamus, structure involved in the “master clock” of circadian rhythms

71
Q

Cerebellum

A

receives sensory input from the spinal cord, motor information from the cerebral cortex, and input about balance from inner ear receptors
Control of movement on the ipsilateral side of the body (damage causes motor deficits on the same side)

72
Q

hindbrain

A

the lower part of the brainstem, comprising the cerebellum, pons, and medulla oblongata

73
Q

Brainstem

A

inferior (behind) to superior medulla, pons, and midbrain, Contains all nerve connecting the spinal cord to the cerebrum, receives sensory info from head, neck, and face, involved in hearing, taste, and balance

74
Q

Medulla

A

Located in the rostral region of brainstem, regulated bp, respiration, breathing, swallowing, digestion, heart, and blood vessels

75
Q

Pons

A

links to cerebellum and cerebrum and relays info from cerebral cortex to cerebellum, functions with sleep, arousal, facial movements, breathing

76
Q

Midbrain

A

topmost part of the brainstem, the connection central between the brain and the spinal cord, controls response to sight (eye movements), relay station of auditory and visual signals, motor control of some skeletal muscles

77
Q

Tectum

A

Roof of midbrain

78
Q

Tegmentum

A

Floor of midbrain

79
Q

Limbic system

A

functional/evolutionary division, group of structures in center of brain, superior to the brainstem, includes hypothalamus, pituitary, hippocampus, hippocampal gyrus, amygdala

80
Q

Mammillary bodies

A

brainstem nuclei on the posteroinferior aspect of the hypothalamus, role in memory

81
Q

Papez’s circuit

A

Heuristic device, describe disorders of emotion, refers to neuroanatomical structures involves in emotion and memory (e.g., hippocampus, cingulate, mammillary bodies, fimbria, and insula)

82
Q

Carotid arteries

A

vessels run along front of the neck, one right and left, Stroke in this area = changes with speech, vision, sensation

83
Q

Vertebral arteries

A

vessels run along back of neck, right and left sides
Join to form one basilar artery
Stroke in this area = changes level of wakefulness, problems with muscle movement and coordination, speech changes, and vision problems

84
Q

Circle of Willis

A

at the base of the brain, carotid and vertebral arteries come together, make circle of arteries that provide many paths for blood to supply O2 and nutrient to brain

85
Q

Anterior Cerebral Artery

A

vessel supplies blood to the front part of brain/frontal lobe. Stroke = leg weakness, difficulty thinking and making decisions, changes in personality

86
Q

Middle cerebral artery

A

vessel supplies blood to middle part of brain,
Most common for strokes,
Stroke = paralysis on one side of body, changes in sensation, blindness (either side), language problems (e.g., difficulty forming words and sentences, difficulty understanding what others are saying), upper extremity hemiparesis, aphasia, and neglect

87
Q

apraxia

A

impaired ability to carry out motor abilities despite intact motor function