Neurological Disorders - CNS: Brain Flashcards

(44 cards)

1
Q

Parkinson’s Disease - Pathophysiology

A
  • Loss of dopamine stores
  • Results in more excitatory neurotransmitters
  • Imbalance affects voluntary movement
  • Males greater than women
  • 15% early onset genetic mutation
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2
Q

Parkinson’s Disease - CMs

A
  • 4 Cardinal Signs
    > tremor
    > rigidity
    > bradykinesia/akinesia
    > postural instability
  • Types:
    > tremor dominate
    > non-tremor dominate; a kinetic-rigid & postural instability
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3
Q

Parkinson’s Disease - Stage 1

A
  • Initial Stage
    > unilateral limb involvement
    > minimal weakness
    > hand & arm trembling
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4
Q

Parkinson’s Disease - Stage 2

A
  • Mild Stage
    > bilateral limb involvement
    > masklike face
    > slow, shuffling gain
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5
Q

Parkinson’s Disease - Stage 3

A
  • Moderate Disease
    > postural instability; not able to walk very well
    > incr gait disturbances
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6
Q

Parkinson’s Disease - Stage 4

A
  • Severe Disability
    > akinesia
    > rigidity
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7
Q

Parkinson’s Disease - Stage 5

A
  • Complete ADL Dependence
    > in later stages, psychiatric components come into play
    > psychosis
    > hallucinations
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8
Q

Parkinson’s Disease - Diagnostics

A
  • Hx
  • 4 cardinal signs (2 of 4)
  • Diagnosis confirmed by a positive response to levodopa trial
  • PET scan; rule out
  • Single-photon emission CT; rule out
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9
Q

Parkinson’s Disease - Medical Management

A
  • Pharmacotherapy
    > Levodopa; most effective; converts to dopamine; relieves manis
  • Surgical Treatment
    > deep brain stimulation (DBS)
    > electrode implanted/blocks anticholinergic release
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10
Q

Parkinson’s Disease - Nursing Diagnosis

A
  • Impaired physical mobility
  • Self-care deficits
  • Constipation; due to lack of mobility
  • Impaired nutrition
  • Risk for injury
  • Impaired verbal communication
  • Knowledge deficit; family & pt
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11
Q

Parkinson’s Disease - Nursing Interventions

A
  • Improve mobility (w/in safety)
  • Enhancing self care activities
  • Improved bowel elimination; mobility & stool softeners
  • Improved nutrition; aspiration risk
  • Enhanced swallowing
  • Assistive devices
  • Family/pt education; PT/OT/Speech
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12
Q

Dementia - Pathophysiology

A
  • Cognitive, functional, & behavioral changes eventually destroy a person’s ability to function
    > subtle in onset; progress slowly
  • Not a normal part of aging
  • Non-Alzheimer dementias
    > vascular dementia
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13
Q

Alzheimer’s

A
  • Specific neuropathologic & biochemical changes tht interfere w/ neurotransmission
  • Most common dementia
  • Early onset (familial 40-65yrs)
  • Late onset (>65yrs)
  • Risk factors:
    > age
    > gender
    > genetics
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14
Q

Dementia (Alzheimer’s) - CMs

stage 1

A
  • Early (mild), Stage I
  • first symptoms up to 4yrs
    > independent in ADLs
    > denies presence of symptoms
    > forgets names; misplaces household items
    > has short-term memory loss & difficulty recalling new info
    > shows subtle changes in personality & behavior
    > loses initiative & is less engaged in social relationships
    > has mild impaired cognition & problems w/ judgement
    > Demonstrates dcrd performance; especially when stressed
    > unable to travel alone to new destinations
    > often has dcrd sense of smell
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15
Q

Dementia (Alzheimer’s) - CMs

stage 2

A
  • Middle (moderate), Stage II
  • 2-3yrs
    > has impairment of all cognitive funcs
    > demonstrates problems w/ handling or unable to handle money & finances
    > is disoriented to time, place, & event
    > is possibly depressed and/or agitated
    > is incringly dependent in ADLs
    > has speech & language deficits; less talkative, dcrd use of vocab, incringly nonfluent, & eventually aphasic
    > incontinent
    > psychotic behaviors; delusions, hallucinations, paranoia
    > has episodes of wandering; trouble sleeping
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16
Q

Dementia (Alzheimer’s) - CMs

stage 3

A
  • Late (severe)
  • Stage III
    > completely incapacitated; bedridden
    > totally dependent in ADLs
    > has loss of mobility & verbal skills
    > possibly has seizures & tremors
    > has agnosia
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17
Q

Dementia (Alzheimer’s) - CMs

extra info

A
  • Pts can show manis from any stage
  • Pts can have issues from any stages at anytime
    > mix & match
    > slide btwn stages
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18
Q

Dementia (Alzheimer’s) - Diagnostics

A
  • Hx
  • Physical assessment/manis
  • Psychosocial assessment
  • Lab; rule out
  • Radiological; rule out
19
Q

Dementia (Alzheimer’s) - Medical Surgical Treatment

A
  • Behavioral management structured envir’t
  • Cognitive stimulation
  • Memory training
  • Validation therapy (orientation)
  • Redirection
  • Pharm therapies
    > Donepezil (Aricept); improves symptoms
20
Q

Dementia (Alzheimer’s) - Nursing Management

A
  • Supporting cognitive func
  • Promoting physical safety
  • Promoting independence in self-care activities
  • Reducing anxiety & agitation
  • Improving communication
  • Providing for socialization & intimacy needs
  • Promoting adequate nutrition
  • Promoting balanced activity & rest
  • Home, community, & transitional care
21
Q

Meningitis - Pathophysiology

A
  • Inflammation of the meninges, which cover & protect the brain & spinal cord
  • Infection through bloodstream or direct spread
    > proliferates in CSF
    > inflamm/incr ICP
22
Q

Meningitis - Complications

A
  • Hemorrhage/vascular necrosis (Waterhouse-Friderichsen syndrome)
  • Circulatory collapse
  • Septic shock
  • Blindness/deafness
  • Paralysis/seizures
  • Hydrocephalus
23
Q

Meningitis - CMs

A
  • Severe headache
    > incrd ICP
  • Neck immobility (nuchal rigidity)
  • Photophobia
  • Kernig sign: pushing knees past 135 degrees laying down
  • Brudzinski sign: reflexive flexion of knees & hips following passive neck flexion
24
Q

Meningitis - Diagnostics

A
  • Identify causative agent
  • Lumbar puncture
    > CSF culture & sensitivity; viral, bacterial, fungal
  • Blood culture & sensitivity
  • CT if altered LOC
25
Meningitis - Medical Surgical Treatment
- Broad-spectrum antibiotic - Steroids - IV fluid vol expanders; shock - Anticonvulsants; seizures - Prophylaxis treatment for those in close contact w/ meningitis infected pts - Vaccinations
26
Meningitis - Nursing Diagnosis
- Ineffective airway clearance - Impaired comfort - Impaired mobility - Acute pain - Risk for aspiration - Risk for injury
27
Meningitis - Nursing Interventions
- Ensure airway - Pain management - I&O - Encourage fluid intake - Close neurologic monitoring - Collaborative w/ physician
28
Meningitis - Nursing Care
- Infection control precautions 24hrs after initiation of antibiotic therapy - Assisting w/ pain management - Assisting w/ getting rest in a quiet, dark room - Treat elevated temp w/ antipyretics & cooling blankets - Maintain hydration orally or peripherally - Protecting from injury secondary to seizure or alt LOC - Monitor: daily weight, electrolytes, urine vol, specific gracity, osmolality; esp if SIADH is suspected - Prevent comps of immobility; pressure ulcers & pneum
29
Encephalitis - Pathophysiology
- **Involves local necrotizing hemorrhage tht becomes more generalized, followed by edema** - viral, bacterial, fungal - herpes simplex most common cause in US
30
Encephalitis - CMs
- Fever, headache, confusion, & hallucinations - Focal neurologic symptoms reflect areas of cerebral inflamm & necrosis
31
Encephalitis - Medical Surgical Interventions
- Diagnosis: MRI, LP, EEG - Med: antiviral; Acyclovir - Comps: atelectasis or pneum
32
Encephalitis - Nursing Interventions
Same as meningitis
33
Traumatic Brain Injury - Pathophysiology
- **Primary** > direct contact to head/brain during instant of initial injury - **Secondary** > inadequate delivery of nutrients & oxygen to cells - Results in incrd ICP
34
Traumatic Brain Injury - Complications
- Dcrd cerebral perfusion - Cerebral edema & herniation - Imapired oxygenation & ventilation - Impaired fluid, electrolyte, & nutritional balance - Risk of posttraumatic seizures
35
Traumatic Brain Injury - Medical Surgical Treatment
- Diagnostics: neuro exam; CT, MRI, PET - Treat incrd ICP - Supportive measures - Brain death; potential donor
36
Traumatic Brain Injury - Supportive Measures
- Vent support - Airway support - Seizure prevention - Fluid & electrolyte maintenance, nutritional support - Pain & anxiety - NG tube
37
Traumatic Brain Injury - Nursing Diagnosis
- Ineffective airway clearance & impaired gas exchange - Risk for ineffective cerebral tissue perfusion - Deficient fluid - Imbalanced nutrition; less than body requirements - Risk for injury - Risk for impaired skin integrity
38
Traumatic Brain Injury - Nursing Interventions
- ICU admin - Maintain airway - **Monitor neuro func** > GSC - Monitor fluid & electrolytes - Promote adequate nutrition - Prevent injury - Maintain body temps - Maintain skin integrity
39
Brain Tumors - Pathophysiology
- **Occupies space w/in skull, growing as a spherical mass or diffusely infiltrating tissue** > incrd ICP > seizure activity > hydrocephalus - Primary - Secondary
40
Brain Tumors - CMs
- Incrd ICP > headache > vomiting > visual disturbances > seizures - Localized manis
41
Brain Tumors - Diagnostics
- Neuologic exam - CT scan - MRI - Computer assisted stereotactic biopsy - PET scan
42
Brain Tumors - Medical Surgical Treatment
- Surgical management - Radiation therapy - Chemotherapy - Pharmacologic therapy
43
Brain Tumors - Nursing Diagnosis
- Acute confusion - Fear - Dcrd intracranial adaptive capacity - Acute pain - Vision loss - Risk for injury
44
Brain Tumors - Nursing Interventions
- Assess neuro status/reorient - Alleviate fear - Treat pain - Assess for visual acuity - Provide safe envir't