- NEUROLOGICAL PRESENTATIONS - Flashcards

1
Q

Discuss the function of the nervous system

A

To co-ordinate and regulate:

  • sensory input
  • integration
  • motor output
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2
Q

Demonstrate the assessment of the nervous system

A

Neurological history includes:

  • clinical manifestations
  • associated complaints
  • precipitating factors
  • progression
  • familial history

Assessment:

  • GCS/AVPU
  • Pupil size, equality and reactivity
  • Limb strength
  • Cranial nerves
  • Seizures
  • Pain
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3
Q

Outline the characteristics of stage 1 of increased ICP/ICHTN

A

Stage 1:

  • vasoconstriction and external compression of venous system (compensatory mechanism)
  • ICP may not change
  • Few clinical manifestations evident
  • If ICP monitered may see an increase in pressure that takes longer to return to baseline
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4
Q

Discuss compensatory mechanisms critical to preserving the integrity of the brain

A
  • shunting of blood

- regulation of CSF

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5
Q

Differentiate between the following brain disorders; viral and bacterial meningitis and encephalitis

A

Encephalitis - inflammation of brain parenchyma, caused but bacteria and viruses, diagnosed by bloods, treated with ampicillin and cephalosporins, photophobia and stiff neck

Meningitis - inflammation of the protective layers covering the brain, caused by viral agents, neuroimaging usually required to diagnose and bloods, treated with acyclovir, seizures and behavioural changes

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6
Q

Discuss the assessment of an ACS

A

PEARL, GCS, Limb strength, neurological S+S and history of PP

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7
Q

Discuss the management of an ACS

A
  • High vis cubicle
  • Regular neuro obs
  • Pathology, including urine
  • Investigations (CTB, MRI)
  • Differential Dx
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8
Q

Discuss the assessment of a TIA or stroke

A

Pupil size and reactivity, GCS, Limb strength, neurological S+S and history of PP, presence/absence of raised ICP

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9
Q

Discuss the management of a TIA

A

Referred to as ‘minor stroke’ or ‘mini stroke’:
- When clinical manifestations are present but resolve
within 24 hours
- TIA’s require emergency treatment
- Needs prompt investigation

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10
Q

Discuss the management of a hemorrhagic stroke

A
  • intubation if low GCS
  • BSL management
  • cessation and reversal of anticoagulants
  • craniotomy
  • spinal tap to relieve ICP
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11
Q

Discuss the management of a non-hemorrhagic stroke

A
  • aspirin or other anticoagulants
  • Tissue plasminogen activator (tPA)
  • surgical intervention
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12
Q

Discuss the management of a traumatic brain injury

A
Protect the airway & oxygenate. 
Ventilate to normocapnia. 
Correct hypovolaemia and hypotension. 
CT Scan when appropriate. 
Neurosurgery if indicated. 
Intensive Care for further monitoring and management.
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13
Q

Discuss the management of seizures

A
  • protect airway
  • witnessing (time, length)
  • ?bite block
  • safe space
  • medications (benzodiazepines, phenytoin, sodium valporate, keppra, barbitates, propofol)
Investigations:
Neuroimaging
Lumbar puncture
Toxicology
EEG to monitor for seizures (especially NCSE)
Anticonvulsant
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14
Q

Discuss the assessment of a traumatic brain injury

A
  • ABCD
  • avoid hypotension and hypoxia
  • GCS and brief neurological Ax
  • history and MOI
  • vitals
  • full neuro assessment
  • external head and neck examination
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15
Q

Discuss the assessment of seizures

A
  • description of the seizure phenomena
  • time of seizure and treatment
  • previous seizures
  • stroke or other epilepsy risk factors
  • other medical conditions
  • current medications
  • neurological assessment
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16
Q

Discuss the management of meningitis

A
  • Bacterial meningitis is a medical emergency
    Airway:
    – assess LOC
    – nil orally
    – intubate if GCS < 8 or signs of raised ICP

Breathing:
– assess WOB, RR, SaO2
– supplemental O2 if SaO2 < 95%

Circulation:
– vital signs
– FBC
– fluid management

Disability:
– antibiotic (don’t wait for specimens)
– analgesia
– positioning
– dark room and cover for eyes
– minimal stimulation
– seizure management
– antipyretics
– skin care
– nutritional support
17
Q

Discuss the clinical manifestations of Guillian-Barre syndrome

A
  • sudden bilateral weakness (days or weeks)
  • SOB
  • unable to perform previously effortless tasks, such as swallowing
  • cramps and body aches
  • ascending (usually temporary) paralysis
  • areflexia
  • absence of fever
  • Loss of vasomotor control
  • Fluctuating BP
  • Postural hypotension
  • Cardiac dysrhythmia
18
Q

Discuss the management of Guillian-Barre syndrome

A
Symptomatic management / supportive care:
 - airway maintenance (secretions can cause choking or pneumonia)
 - ventilation if respiratory failure
 - IDC
 - pain relief
Treatment:
 - Plasmaphoresis
 - High dose immunoglobulin therapy
19
Q

Discuss the difference between an epidural, subdural and intracranial bleed

A

EDH - between the skull and the dura, (commonly from meningeal artery)

SDH - between the dura and the arachnoid mater (commonly trauma, elderly, shaken baby syndrome)

Intracranial - bleed in the parenchyma or meninges (usually caused by hypertension, aneurysm, drugs etc)

20
Q

Discuss the use pf thrombolysis in a stroke

A

Inclusion Criteria:

  • BSL 2.7 – 22 mmol/L
  • Ischaemic stroke on CT brain
  • rt-PA administration < 3 hours post onset of symptoms
Exclusion Criteria:
Onset of symptoms > 3 hours
- BSL < 2.7 or >22 mmol/L
- Seizure at onset
- AMI > 7 days or < 3 months
- Stroke or serious head trauma within 3 months
- Major surgery within 14 days
- GIT or urinary haemorrhage in last 21 days
Pregnant
- Check haemorrhage risk (INR > 1.5 on warfarin or other anticoagulant)
- Platelets < 100000/mm3
- Systolic BP >185 despite Rx
- Diastolic BP >110 despite Rx
21
Q

Discuss the nursing management of a pt with a raised ICP

A
  • Treatment depends on underlying cause and focus is removing the cause.

AIRWAY:
- Intubate if GCS<8

BREATHING:

  • monitor breathing pattern
  • Apply O2 if SaO2 < 95%
  • aim for PaCO2 @35mmHg

CIRCULATION:

  • hypotension treated with fluid +/- Inotropes
  • Aim for a systolic BP>90mmHg
  • Osmotic Diuretic eg Mannitol 20%
  • Steroids

DISABILITY:

  • position @30-40 degree angle
  • take measures to prevent (coughing, vomiting, shivering, posturing)
  • control seizure activity
  • adequate sedation
  • reduce noxious stimuli
22
Q

Outline the characteristics of stage 2 of increased ICP/ICHTN

A
  • Inrease in ICP exceeds compensatory mechanisms
  • Oxygenation compromised
  • Systemic arterial vasoconstriction to increase BP
  • Clinical manifestations subtle and transient (episodes of confusion, restlessness, drowsiness, slight pupil changes, slight respiratory changes)
23
Q

Outline the characteristics of stage 3 of increased ICP/ICHTN

A
  • ICP begins to reach arterial pressures
  • Brain experiences hypoxia, hypercapnia and acidosis
  • Rapid deterioration in condition
  • Clinical manifestations: decreased GCS, central neurogenic hypoventilation, widened pulse pressure, bradycardia, small sluggish pupils
24
Q

Outline the characteristics of stage 4 of increased ICP/ICHTN

A
  • Herniation of brain tissue
  • Compromised blood supply leading to further hypoxia and ischaemia
  • Small heamorrhages develop
  • Obstructive hydrocephalus may develop
  • Marked and rapid increase in ICP
  • MAP = ICP
  • Cerebral blood flow ceases
25
Q

What is a normal ICP

A

5-15mmHg

26
Q

What is the calculation for CPP (cerebral perfusion pressure)

A

CPP = MAP minus ICP

27
Q

What is the normal range for CPP

A

60-80mmHg

28
Q

Outline the clinical manifestations of an increased ICP

A
  • Altered conscious state (restless, agitation, confusion drowsiness unresponsive)
  • Headache
  • Nausea and vomiting
  • Pupil changes
  • Cushing’s Reflex (Raised systolic BP (widening pulse pressure), Bradycardia, Irregular respirations (Cheyne-Stokes respirations)
  • Abnormal posturing
29
Q

List the clinical manifestations of meningitis

A
  1. Fever
  2. Neck stiffness / Nuchal rigidity
  3. Severe headache
  4. Nausea and vomiting
  5. Photophobia
  6. Decreased level of consciousness
  7. Positive Kernig’s sign
  8. Positive Brudzinski’s sign
  9. Petechial skin rash (if meningococcal)