Neurology

Question 1

What is progression of GBS, and what are the residual symptoms?

Answer 1

Generally begin to recover within 6 weeks, and completely recover by 12mo

RF for poor prognosis: age >40, preceding diarrhea (aetiology?), severity of symptoms

Residual symptoms
- fatigue
- pain, parasthesia
- weakness (20% will be unable to walk independently)

Treatment related fluctuations
- worsening of symptoms after initial recovery
- treatment: repeat the treatment that worked initially

Question 2

What is the process that usually kills people with GBS?

Answer 2

• cardiac arrest (autonomic disturbance)
• respiratory failure
• respiratory infection
• PE

Question 3

What are the triggers for GBS?

Answer 3

Infectious
- Campylobacter jejuni
- CMV/EBV, myocplasma pnuemonia, H influenza, hepatitis E

Vaccines (risk of GBS still higher with flu than the vaccine)

Surgical trauma

ISx

PRegnancy