Neurology

Question 1

Peripheral neuropathy - sensory - causes

Answer 1

Metabolic - DM, uraemia, hypothyroid, B12
Toxic - ETOH, chemo, medications
Inflammatory - CIDP, sarcoid, RA, vasculitis
Paraneoplastic - solid and paraproteinaema
Hereditary - charcot marie tooth - pes cavus

Question 2

Sensory peripheral neuropathy work up

Answer 2

BM, fundoscopy
FBC (anaemia), U+E, LFT, CRP
B12, TFTs, ESR
Immunoglobulins + serum electrophoresis
HbA1c

Nerve conduction studies and EMG
- axonal vs demyelinating (more likely immune), and ? length dependent (less likely immune).

Question 3

Peripheral neuropathy management

Answer 3

Manage underlying condition
Physio + OT
Podiatry

Question 4

Parkinsons

Question 5

Charcot-Marie-Tooth findings

Answer 5

Sensorimotor peripheral neuropathy
Pes cavus
Wasting - peripheral > proximal

Question 6

Charcot Marie Tooth Genetics

Answer 6

Autosomal Dominant
T1 = demyelinating and most common

Question 7

Spastic paraparesis

Answer 7

C

Question 8

Cerebellar syndrome

Question 9

Myotonic dystrophy

Question 10

Myasthenia gravis

Question 11

Post polio syndrome

Question 12

Acromegaly

Question 13

MND / multifocal motor neuropathy