Neurology Flashcards

1
Q

What percentage of strokes are due to intracranial bleeds?

A

10-20%

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2
Q

What are some risk factors for intracranial bleeds?

A
Hypertension
Head injury 
Aneurysms
Ischaemic stroke --> haemorrhage
Brain tumours
Anti-coagulations ie Warfarin
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3
Q

How might a patient with an intracranial bleed present?

A
Sudden onset headache
Seizures
Reduced consciousness
Weakness
Vomiting
Sudden onset neurological symptoms
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4
Q

What causes a subdural haemorrhage?

A

Rupture of bridging veins

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5
Q

How does a subdural haemorrhage appear on a CT?

A

Crescent shape not limited by cranial sutures

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6
Q

In what population groups are subdural haemorrhages most likely to occur?

Why?

A

Elderly
Alcoholics

Brain more atrophied –> bridging vessels more likely to rupture

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7
Q

A subdural haemorrhage occurs between which layers of the meninges?

A

Dura mater

Arachnoid mater

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8
Q

What usually causes an extradural haemorrhage?

A

Rupture of the middle meningeal artery

Often associated with fracture of the temporal bone

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9
Q

Between what layers of the cranium, does an extradural haemorrhage occur?

A

Skull and dura mater

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10
Q

How does an extradural haemorrhage appear on a CT?

A

Bi-convex shape

Limited by sutures

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11
Q

How does an intracerebral haemorrhage present?

A

Similarly to an ischaemic stroke

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12
Q

What are the principles of managing a patient who has an intracerebral haemorrhage?

A

A-E assessment
Urgent head CT
FBC and clotting (correct any clotting abnormalities)
Management in a stroke unit
? neurosurgical input
Consider intubation, ventilation and ITU if drop GCS
Correct severe hypertension

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13
Q

Where does a SAH occur?

A

Subarachnoid space between the Pia mater and the arachnoid membrane

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14
Q

What symptoms are associated with a SAH?

A

Sudden onset occipital headache “thunder clap”
Neck stiffness
Photophobia
Neurological symptoms - visual changes, speech changes, weakness, seizures, LOC

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15
Q

What are risk factors for SAH?

A
HTN
Smoking
Excessive alcohol consumption
Cocaine
FHx
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16
Q

in what groups of people are SAH most common in?

A

Black people
Females
45-70 years

17
Q

What is SAH particularly associated with?

A

Cocaine use
Sickle cell anaemia
Connective tissue disorders (E-D, Marfans)
Neurofibromatosis

18
Q

What investigations should be performed in patents with ?SAH?

A

Urgent Head CT (hyperattenuation in the subarachnoid space)

If CT negative, after 12 hours –> LP (raised RBC, xanthochromia)

CT/MRI angiography - located site of bleed

19
Q

What ECG changes may be seen in SAH?

A

Inverted T waves

Elevated ST

20
Q

How should a patient with SAH be managed?

A

Neurosurgically

  • Endovascular coiling
  • Neurosurgical clipping

MDT approach (SALT, physio, OT, nursing)

21
Q

What drug should be prescribed to patients with SAH to prevent further complications?

A

Nimodipine (Ca channel blocker - prevents vasospasm)

22
Q

Define a TIA

A

Transient neurological dysfunction secondary to ischaemia without infarction

23
Q

What is a crescendo TIA?

A

Two or more TIAs occurring within a week - carries a high risk of progressing to a stroke

24
Q

How does a stroke present?

A
Sudden onset of neurological symptoms which are asymmetrical 
Sudden weakness of limbs
Sudden facial weakness
Sudden dysphagia
Sudden visual/sensory changes
25
Give some risk factors of stroke
``` Cardiovascular disease - angina, MI, PVD Previous stroke, TIA AF Carotid artery disease DM Vasculitis Thrombocytopenia ``` Modifiable: HTN Smoking OCCP
26
What scoring tool can be used in hospital to determine the likelihood of a patient having a stroke?
ROSIER
27
What scoring tool can be used to assess the likelihood of a patient with a suspected TIA having a subsequent stroke?
ABCD2
28
Define the ABCD2
``` A = Age (>60 = 1 pt) B = BP (>140/90 = 1 pt) C = Clinical features (unilateral weakness = 2 pt; dysphagia without weakness = 1 pt) D = Duration (> 60 min = 2 pt; 10-60 min = 1 pt; <10 min = 0 pt) D = Diabetes = 1 pt ```
29
What is the significance of a ABCD2 score in terms of need to see a specialist?
``` <3 = specialist assessment within 1 week >3 = specialist assessment within 1 week ```
30
How should a stroke be managed?
A - E assessment Exclude hyperglycaemia Urgent Head CT (exclude haemorrhagic cause) Aspirin 300mg (only if no haemorrhage) - continue for 2 weeks Admit to specialist Stroke Unit
31
What is the timeframe for potential thrombolysis treatment in the management of ischaemic stroke?
Within 4.5 hours of symptoms
32
What is the timeframe for potential thrombectomy in the management of ischaemic stroke ?
Within 6 hours
33
How should a TIA be managed?
300mg Aspirin Perform ABCD2 score Secondary prevention
34
What are the secondary prevention methods in TIA management?
Aspirin for 2 weeks then... Clopidogrel 75mg OD (dipyridamole + aspirin) Atorvastatin 80mg Assess for carotid artery disease --> stenting or carotid endartectomy Treat modifiable risk factors
35
Who makes up the MDT in a stroke patient?
``` Nurses SALT OT Physios Social services Dieticians Optometery and ophthalmology Psychology Orthotics ```