Neurology Flashcards

1
Q

What is childhood epilepsy?

A

Epilepsy is a brain condition that causes a child to have seizures

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2
Q

What are the different types of focal seizures?

A

Simple focal seizure

Complex focal seizure

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3
Q

What are the symptoms of simple focal seizure?

A
  1. The symptoms depend on which area of the brain is affected.
  2. The seizure activity is limited to an isolated muscle group. For example, it may only include the fingers, or larger muscles in the arms and legs.
  3. Your child may also have sweating, nausea, or become pale.
  4. Your child won’t lose consciousness in this type of seizure.
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4
Q

What are the symptoms of complex focal seizures?

A
  1. This type of seizure often occurs in the area of the brain that controls emotion and memory function (temporal lobe).
  2. Your child will likely lose consciousness.
  3. These may range from gagging, lip smacking, running, screaming, crying, or laughing.
  4. Your child may be tired or sleepy after the seizure.
  5. This is called the postictal period.
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5
Q

What are the different types of generalised seizures?

A
  1. Absence seizures (petit mal)
  2. Atonic seizures
  3. Generalised tonic-clonic seizures (grand-mal)
  4. Myoclonic seizures
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6
Q

What are the symptoms of absence seizures?

How long do they last?

A

This is also called petit mal seizure

Changed state of consciousness and staring
Mouth or face may twitch or eyes may blink rapidly
Not recall what just occurred
These seizures may occur several times a day

The seizure usually lasts no longer than 30 seconds

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7
Q

At what age do absence seizures start?

A

Between the ages of 4 and 12

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8
Q

What are the symptoms of an atonic seizure?

A

This is also called a drop attack

With an atonic seizure, your child has a sudden loss of muscle tone and may fall from a standing position

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9
Q

What are the symptoms of a generalised tonic-clonic seizure?

A

This is also called grand mal seizure

The classic form of this kind of seizure has 5 distinct phases.

  1. Flex (contract)
  2. Extend (straighten out)
  3. Tremor (shake)
  4. Contraction and relaxation of the muscles (clonic period)
  5. Postictal period
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10
Q

What are the symptoms of myoclonic seizures?

A

Quick movements or sudden jerking of a group of muscles

These seizures tend to occur in clusters

this means that they may occur several times a day, or for several days in a row.

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11
Q

What are the causes of seizures in a child?

A

An imbalance of nerve-signaling brain chemicals (neurotransmitters)

Brain tumor

Stroke

Brain damage from illness or injury

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12
Q

How are seizures diagnosed in a child?

A

Asked for any of the following:
Recent fever or infection
Head injury
Congenital health conditions
Preterm birth
Recent medicines

EEG
Absence seizures - 3Hz
Lennox-Gastaut syndrome - 1.5 Hz - 2.5 HZ

Spinal tap

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13
Q

What are infantile spasms (West’s syndrome)?

A

Brief spasms beginning in first few (4-6) months of life; M>F

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14
Q

What are the symptoms of infantile spasms?

A

Flexion of head, trunk, limbs → extension of arms

(Salaam attack);

last 1-2 secs, repeat up to 50 times

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15
Q

How do you diagnose infantile spasms?

A
  1. Progressive mental handicap
  2. EEG: hypsarrhythmia
  3. Usually 2nd to serious neurological abnormality (e.g. TS, encephalitis, birth asphyxia) or may be cryptogenic
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16
Q

When do typical (petit mal) absence seizures affect children?

A

4-8 years

17
Q

What are the symptoms of typical (petit mal) absence seizures?

A

Duration few-30 secs

No warning

Quick recovery

Often many per day

18
Q

How do you diagnose absence seizures?

A

EEG: 3Hz generalized, symmetrical

19
Q

What is the treatment for typical (petit mal) abence seizures?

A

Sodium valproate

Ethosuximide

20
Q

What is the treatment for infantile spasms?

A
  1. Vigabatrin is now considered first-line therapy
  2. ACTH is also used
21
Q

What is Lennox-Gastaut Syndrome?

A

Lennox-Gastaut syndrome (LGS) is a type of epilepsy.

Patients with LGS experience many different types of seizures

22
Q

What are the symptoms of Lennox-Gastaut Syndrome?

A

Tonic
Stiffening of the body

Atonic
Temporary loss of muscle tone and consciousness, causing the patient to fall

Atypical absence
Staring episodes

Myoclonic
Sudden muscle jerks

23
Q

What is the diagnosis for Lennox-Gastaut syndrome?

A

EEG: Slow spike

24
Q

What is the treatment for all seizures?

A

Generalised tonic-clonic seizures
Sodium valproate
Second line: lamotrigine, carbamazepine

Absence seizures* (Petit mal)
Sodium valproate or ethosuximide

Myoclonic seizures**
Sodium valproate
Second line: clonazepam, lamotrigine

Focal seizures
Carbamazepine or lamotrigine

Second line: levetiracetam, oxcarbazepine or sodium valproate

25
Q

What is a febrile convulsion?

A

A febrile seizure is a convulsion in a child caused by a spike in body temperature, often from an infection

26
Q

What are the clinical features of a febrile convulsion?

A

Usually occur early in a viral infection as the temperature rises rapidly

Seizures are usually brief, lasting less than 5 minutes

Are most commonly tonic-clonic

27
Q

What are the different types of febrile convulsions?

A

Simple
< 15 minutes
Generalised seizure
Typically no recurrence within 24 hours
Should be complete recovery within an hour

Complex
15 - 30 minutes
Focal seizure
May have repeat seizures within 24 hour

Febrile status epilepticus
> 30 minutes

28
Q

How long should a parent wait before phoning an ambulence in febrile convulsions?

A

More than 5 minutes

29
Q

Although febrile convulsions are caused by high temperatures, what has no effect on preventing them?

A

Antipyretics