Neurology & Psychiatry Flashcards
Dementia, Depression, Altered Mental Status, Syncope, SUD (24 cards)
What is the mnemonic for syncope causes?
HEAD: Hypoxia, Epilepsy, Anxiety, Dysautonomia
HEART: Heart disease, Embolism, Aortic stenosis, Rhythm abnormality, Tachycardia/bradycardia.
How is syncope evaluated (4)?
- Orthostatics
- ECG
- Holter monitor
- echo (if structural heart disease suspected)
What is the treatment for vasovagal syncope (3)?
- Reassurance
- hydration
- beta-blockers (if recurrent)
- If they ask for the most ACCURATE test for Alzheimer →
- Test for clinical diagnosis →
- Brain biopsy
- MRI
Dementia tx
- Mild-to-Moderate Dementia → Acetylcholinesterase inhibitors (Donepezil, Rivastigmine, Galantamine)
- Moderate-to-Severe Dementia → NMDA receptor antagonist (Memantine)
Workup for dementia (5)
- MMSE (Mini-Mental Status Exam) → Quick screening
- MoCA (Montreal Cognitive Assessment) → More sensitive for early dementia
- Neuroimaging (CT/MRI) → Rule out reversible causes (normal pressure hydrocephalus, tumors, strokes)
- B12 & TSH → Rule out metabolic causes
- RPR → Rule out neurosyphilis
What are the items on the SAD PERSONS suicide risk factors?
When would you treat a patient indefinitely for major depression?
If patient had ≥3 major depressive episodes
(first episode = tx for 6 months)
first line depression tx
- fluoxetine
- sertraline
- venlafaxine
SUD evaluation
- CAGE questions
- UA tox screen
tx for opioid use disorder
tx for alcohol use disorder
- Opioid Use Disorder → Methadone or Buprenorphine/Naloxone (Suboxone)
- Alcohol Use Disorder → Naltrexone (first-line), Disulfiram (second-line, for abstinent patients)
Prognosis: SUD
Relapse is common → Best outcomes with long-term therapy (MAT, therapy, social support)
timeline of alcohol w/d
- 6-12 hours: tremor, HA, anxiety
- 12-48 hours: seizure
- 48-96 hours: DTs (hallucination, fever, autonomic instability)
delirium tremens tx
IV benzos
Ddx for altered mental status (AMS)
AEIOU TIPS mnemonic
Alcohol
Electrolytes
Infection
Overdose
Uremia
Trauma
Insulin
Poisoning
Stroke
If a comatose patient is found down, give …
“Coma Cocktail” = Dextrose (Glucose), Thiamine, Naloxone!
Triptan contraindications (3)
- CAD
- uncontrolled HTN
- stroke
migraine abortive treatment
NSAIDs
then triptans
Other than periorbital pain, lacrimation and rhinorrea, what are two other signs of cluster headache?
circadian pattern
ptosis
which headache can be caused by sex?
subarachnoid hemorrhage (SAH) - thunderclap headache
Red flag symptoms of headache?
SNOOP:
Systemic sx
Neuro Deficit
Onset Sudden
Older age > 50
Pattern change or Progressive
First-line treatment for cluster headaches?
- 100% oxygen
- subQ sumatriptan
(prevent with Verapamil)
Tx to prevent cluster headaches
verapamil
(first line to tx acute: O2 + subQ sumatriptan)
MCC of rebound headaches (caused by overuse of which 3 meds?)
- NSAIDs
- Acetominophen
- Triptans