Neuromuscular Diseases Flashcards
Do not give Sux to these patients: (3)
burn victims
immobile
paraplegics
Why is Sux bad for burn victims, paraplegic, and immobile pts?
extra junctional receptors
Sux binds to these excessive receptors and causes hyperkalemia.
What motor neurons originate in the cerebral cortex and carry motor information down the final common pathway?
upper motor neuron
What are upper motor neuron lesions characterized by? (4)
spasticity
paralysis
weakness
exaggerated reflexes
What tyype of lesion is characterized by spastic paralysis?
upper motor neuron
What tracts are responsible for fine movements?
corticospinal tracts
What upper motor neurons:
- start in the brainstem
- innervate the muscles of chewing
- responsible for pharyngeal and laryngeal movements responsible for the face and jaw musculature
- responsible for protecting the airway?
corticobulbar tracts
What motor neurons connect upper motor neurons from the brainstem and spinal cord to the end muscle?
lower motor neuron
What are lower motor neuron lesions characterized by? (4)
- fasciculation
- paralysis
- weakness atrophy
- flaccid reflexes
What lesion results in flaccid paralysis?
lower motor neuron
Where do motor cortex neurons synapse? (2)
brainstem, or
ventral horn of spinal cord
What is an electrically insulating phospholipid layer that surrounds axons of neurons?
myelin
What cells supply the myelin for peripheral nerves?
Schwann cells
What neuro compromised patient can safely be given Sux?
myasthenia gravis
What is an autoimmune disease with antibodies against the acetylcholine receptors of the motor-endplate?
myasthenia gravis
