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Physiology > Neuromuscular Junction > Flashcards

Neuromuscular Junction Flashcards

1
Q

How many acetylcholine molecules are needed to open the ligand gated channels?

A

2

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2
Q

What are some drugs that mimic acetylcholine?

A

Methacholine, Carbachol and Nicotine

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3
Q

How does Methacholine, Carbachol and Nicotine drugs work?

A

They are replacement drugs that are can not be broken down by acetylcholinesterase. Do cause spasms

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4
Q

What are examples of inactive acetylcholinesterase drugs?

A

Neostigmine, physostigmine and diisopropyl fluorophosphates

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5
Q

How do Neostigmine, physostigmine and diisopropyl fluorophosphates work?

A

Inactivate acetylcholinesterase. Can cause spasms

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6
Q

How do Curare work?

A

Prevents passages of impulses from nerve endings into muscles.

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7
Q

What is Myasthenia Gravis?

A

An autoimmune disease that in which antibodies attack acetylcholine receptors. Therefore, end plate potentials are to weak to open voltage gate sodium channels.

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8
Q

Give an example of how Myasthenia Gravis can be resolved for symptom control?

A

Neostigmine can be used to inactive acetylcholinesterase which will increase chances of A.P

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Physiology (4 decks)

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