Neurophysiology II Flashcards

An overview of neuron and action potential

1
Q

Soma

A

Cell body of neuron

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2
Q

Dendrites

A

Branches of neuron specialized to receive signals

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3
Q

Myelin

A

Fat cells located along axon of neuron

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4
Q

Axon

A

Extension of neuron through which electrical signals travel

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5
Q

Axon Terminal

A

Branches of neuron specialized to send signals

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6
Q

Input Zone

A

Where neurons collect, process, and accumulate information

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7
Q

Integration Zone

A

Where the decision to produce a neural signal is made

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8
Q

Conduction Zone

A

Where the electrical signal is transmitted over a great distance

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9
Q

Output Zone

A

Where the neuron transfers information to another neuron

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10
Q

Action Potential

A

When the membrane potential of a specific cell rapidly rises and falls

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11
Q

Sodium Ion Channel

A

Protein through which Na+ passes into the cell
- Concentration of Na+ greater outside of cell than inside

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12
Q

Potassium Ion Channel

A

Protein through which K+ passes
- Concentration of Ka+ greater inside of cell than outside

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13
Q

Sodium-Potassium Pump

A

Binds three sodium ions and a molecule of ATP to pass Na+ through
- new shape allows two K+ bind

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14
Q

Resting Membrane Potential

A

Negative (-65 mv)

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15
Q

Depolarization

A

Increase in membrane potential
- Only voltage-gated Na+ ion channels open
- Na+ ions rush into cell

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16
Q

Repolarization

A

Decrease in membrane potential
- K+ ion channels open
- K+ ions leave the cell
- Na+ ion channels close

17
Q

Hyper-polarized State

A

Membrane potential is below resting state
- Action potential not possible

18
Q

Conduction Velocity

A

The speed of propagation of the action potential
- Dependent on diameter of axon

19
Q

Saltatory Conduction

A

Insulated axon is able to conduct electrical signals over great distances
- Electrical current skips along length of axon
- Increased speed

20
Q

Nodes of Ranvier

A

Reestablishes ion flow on exposed axon with influxes of sodium ions
- Prevents the electrical charge diminishes over long distances

21
Q

Multiple Sclerosis

A

Condition that causes demyelination
- Slower nerve impulses
- Loss of nerve function

22
Q

Synapse / Synaptic Cleft

A

Location where a dendritic spine meets an axon terminal
- Release of neurotransmitters

23
Q

Synaptic Vesicles

A

Composed of phospholipid bilayer
- Holds neurotransmitters before they are released into the synapse

24
Q

Receptors

A

Proteins ( and ion channels) specific to neurotransmitters
- Change shape when bound to neurotransmitters
- Open to allow ions in to neuron

25
Q

Anterograde Transport

A

Transport of synaptic vesicles down from the cell body to the axon terminal

26
Q

Retrograde Transport

A

Transport of synaptic vesicles up from the axon terminal to the cell body

27
Q

Microtubule Network

A

Process by which motor proteins transport synaptic vesicles down the length of the axon
- Requires ATP

28
Q

Gap Junction

A

Synapse that can transmit electrical signals (action potential)
- Ion channels on each neuron are directly linked to each other
- Similar to structures in human heart

29
Q

Refractory Period

A

Period in which another action potential cannot be fired until the membrane potential returns to resting state