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SIU NMB > Neurotransmitters > Flashcards

Neurotransmitters Flashcards

1
Q

Dextromethorphan

A

Glutamate
NMDA antagonist
dissociative
cough suppressant
abuse potential

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2
Q

Ketamine

A

Glutamate
NMDA antagonist
dissociative
sedative
antidepressant
anesthetic
abuse potential

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3
Q

Memantine

A

Glutamate
NMDA antagonist
sedative
Alzheimer’s

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4
Q

Phencyclidine

A

Glumatme
a.k.a. PCP or angel dust
NMDA antagonist
dissociative
abused

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5
Q

Baclofen

A

GABA
GABA-b receptor Agonist
Treats muscle spasms
off-label uses to manage Alcohol cravings and Alcohol-induced anxiety.

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6
Q

Benzodiazepines (drug class)

A

GABA
GABA-a receptor Agonist
Treats seizures, anxiety disorders, insomnia, sedative.

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7
Q

Alprazolam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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8
Q

Clonazepam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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9
Q

Diazepam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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10
Q

Flunitrazepam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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11
Q

Lorazepam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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12
Q

Temazepam

A

GABA
GABA-a receptor Agonist
Benzodiazepine

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13
Q

Zolpidem

A

GABA
GABA-a receptor Agonist
Treats insomnia

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14
Q

Alcohol

A

GABA
GABA-a receptor Agonist

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15
Q

Sodium Oxybate

A

GABA
GABA-a + GABAb Agonist
Gamma-hydroxybutyrate a.k.a. GHB
Treats Narcolepsy with cataplexy, Street drug hypnotic, an endogenous ligand, and GABA precursor.

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16
Q

Flumazenil

A

GABA
GABA-a antagonist
treats Benzodiazepine overdose

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17
Q

Sumatriptan

A

Serotonin
5HT1B and 5HT1D Receptor Agonist
treats migraine symptoms (photophobia, nausea, headache)

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18
Q

Ondansetron

A

Serotonin
5HT3 Receptor Antagonist
treats nausea and vomiting (common use in Emergency Medicine).
Brain Area Postrema

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19
Q

Sertraline

A

Serotonin
SSRI
Treats Depression

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20
Q

Fluoxetine

A

Serotonin
SSRI
Treats Depression

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21
Q

Citalopram

A

Serotonin
SSRI
Treats Depression

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22
Q

Trazodone

A

Serotonin
SSRI
Treats Depression

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23
Q

Escitalopram

A

Serotonin
SSRI
Treats Depression

24
Q

Paroxetine

A

Serotonin
SSRI
Treats Depression

25
Duloxetine
Serotonin Norepinephrine SNRI Treats Depression
26
Venlafaxine
Serotonin Norepinephrine SNRI Treats Depression
27
Ropinirole
Dopamine D2 receptor Agonist Treats Parkinson's and Restless Legs Syndrome
28
Pramipexole
Dopamine D2 + D3 receptor Agonist Treats Parkinson's and Restless Legs Syndrome
29
Quetiapine
Dopamine D2 receptor Anatgonist Treats Schizophrenia and Acute Mania in Bipolar
30
Risperidone
Dopamine D2 receptor Anatgonist Treats Schizophrenia, acute manic episodes in bipolar, autism-associated irritability
31
Aripiprazole
Dopamine D2 receptor partial Agonist (inhibitory) treats schizophrenia and acute manic episodes in bipolar
32
Amphetamine
Dopamine dopamine reuptake transporter inhibitor norepinephrine reuptake transporter inhibitor monoamine oxidase inhibitor
33
Methylphenidate
Dopamine dopamine reuptake transporter inhibitor norepinephrine reuptake transporter inhibitor
34
Cocaine
Dopamine dopamine reuptake transporter inhibitor norepinephrine reuptake transporter inhibitor
35
Albuterol
Norepinephrine Beta2 agonist treats bronchospasm in patients with obstructive airway disease
36
Salmeterol
Norepinephrine Beta2 agonist treats asthma, chronic obstructive pulmonary disease, and bronchospasm
37
Formoterol
Norepinephrine Beta2 agonist treats asthma and COPD
38
Clonidine
Norepinephrine Alpha2 agonist lowers blood pressure, treats attention deficit hyperactivity disorder (ADHD), tics in Tourette Syndrome, cancer pain
39
Tizanidine
Norepinephrine Alpha2 agonist treats muscle spasticity due to multiple sclerosis, spinal cord injury, stroke, amyotrophic lateral sclerosis, and traumatic brain injury
40
Beta-Blockers (drug class)
Norepinephrine Blocks Beta receptors treats hypertension, acute anxiety (off label)
41
Atenolol
Norepinephrine Beta1 antagonist Beta2 antagonist Atenolol treats hypertension, angina pectoris, and acute myocardial infarction
42
Metoprolol
Norepinephrine Beta1 antagonist treats hypertension, angina, myocardial infarction, atrial fibrillation
43
Carvedilol
Norepinephrine Non-selective Beta antagonist treats hypertension, heart failure, myocardial infarction
44
Propranolol
Norepinephrine Beta1 & Beta2 antagonist treats hypertension, angina. Extensive off-label use for acute anxiety sympathetic nervous system responses
45
Nebivolol
Norepinephrine Beta1 antagonist treats hypertension
46
Mirtazapine
Norepinephrine Alpha2 antagonist treats depression
47
Benztropine
Acetylcholine M1 Antagonist Treats Parkinson's Disease
48
Alpha Neurotoxins
Acetylcholine N1 & N2 Antagonist the key component in snake venom Inhibits the neuromuscular junction
49
Donepezil
Acetylcholine Acetylcholinesterase inhibitor treats Alzheimer's Disease
50
Hydrocodone
Opiate system Mu, Kappa, and Delta receptor agonist treats severe pain, cough
51
Tramadol
Opiate system Mu, (likely Kappa, and Delta) receptor agonist treats severe pain
52
Oxycodone
Opiate system Mu, Kappa, and Delta receptor agonist treats severe pain
53
Morphine
Opiate system Mu, Kappa, and Delta receptor agonist treats severe pain
54
Naltrexone
Opiate system Mu receptor antagonist Naltrexone treats alcohol use disorder, opioid dependence, and opiate toxicity
55
Antihistamines
Histamine Histamine Receptor Antagonists treats seasonal allergies
56
Caffeine
Adenosine A2a receptor antagonist
57
Naloxone
Opiate system Mu receptor antagonist Treats acute opiate overdose

SIU NMB (1 decks)

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