Neurotransmitters Flashcards
(12 cards)
Mono amines
Catchecolimenes (epi,norepi,dopamine)
Seritonen
Histamine
Amino acids
Glut
GABA
Glycine
Purines
ATP
Adenosine
Non traditional SN
NO
ENDOCANABINOiDs
Derivatives of arachidonic acid
Reuptake transporters
Glut - k oh out
glut and na in
Other NT
Cl NA and NT in
Vesicle transporter pumps
We have atp h pump and then secondary pump for H out and NT in
Dopamine
Dat : reuptake
Vmat : vesicle loader
Dopamine affects mitochondria via MAO
Tyrosine - L-dopa - tyrosine hydroxylase
L-dopa to dopamine: dopa decarbox
5 types of metabolic receptors
Parkinsince
Schizophrenic
Drug abuse
Ach
Cht : reuptake of ACh
VACHt - vesicle ACh transporter
A + Ch ——- chat —- Acht
Ache - acetylcholine esterase
CHT: choline and sodium transport
Muscarinic
Nicotinic
NMJ
Autonomic
Sleep wake
Alzheimer’s
GABA
Gat : gaba reuptake
Vgat : vesicle loader
Gat3 takes up gaba into glial
GABA broken down to Glu and the Gln in glial
SN1/SN2 leave glial
SAT- back in psn
Gln- glu via pág
Glu - gaba via gad
Glutamate
Glt: transport glut back into neuron
Vglut: vesicle filler uppper
Glt glast: gc uptake
Broken down to Gln
Sn1 sn2: glial cell exit
Sat uptake to psn
Gln-glut PÁG
NE
NET- reuptake
Tyrosine to L-dopa tyrosine hydrox
L-dopa to dopa by dopa decarbox
VMAt puts dopamine into vesicle
Dopamine beta hydroxylase turns into NE
Alpha beta gprotien receptors
Autonomic NS
Attention arousal
Pain perception
Depression anxiety