Neurotransmitters Flashcards
(7 cards)
Neurotransmission
Electrochemical process through which neurons transmit signals essential for both physiological and psychological functions
Neurotransmitters
Chemical messengers present in the nervous system that travel between neurons and stimulate unique reactions
Flow of how neurotransmission occurs
- Action potential goes down the axon of the presynaptic neuron
- Vesicle containing neurotransmitters are stimulated and released into synapse
- Neurotransmitters travels through the synapse and bind to receptors of the postsynaptic neuron dendrites
- An excitatory or inhibitory reaction occurs
- Neurotransmitters release back into synapse, either undergoing reuptake or broken down by enzymes
Excitatory neurotransmitters
Cause postsynaptic neurons to depolarize and fire an action potential (ACh is an excitatory neurotransmitter)
Inhibitory neurotransmitter
Cause postsynaptic neurons to hyperpolarize and prevent the firing of an action potential until it gets back to its resting state (e.g. GABA)
Agonist and 2 types
Any chemical substance that when bound to a receptor site, causes a response in the postsynaptic neuron.
Endogenous agonists = neurotransmitters (found in the body) like ACh
Exogenous agonists = External drugs that mimic a neurotransmitter
Antagonists
Any chemical substance that when bound to a receptor site, block the effects of an agonist neurotransmitter (e.g. Scopolamine on ACh) because it causes the neuron to hyperpolarize and prevent the firing of an action potential