Neurotransmitters and Receptors

Question 1

What do nicotinic ACh R’s do?

Answer 1

open Na/K ch.

Question 2

What are the five ionotropic receptors?

Answer 2

ACh nicotinic, Serotonin-5HT3, glutamate-KA,AMPA,NMDA, GABA-A, and Glycine

Question 3

What are the two groups of receptors for dopamine? What does each group do?

Answer 3

D1, D5 (metab.) - stimulate AC

D2,D3,D4 (metab.) - inhibit AC

Question 4

What are the 3 types of receptors for NE and E?

Answer 4

α1, α2, and β1-3 are adrenergic metab.

Question 5

What do each NE, E receptor do?

Answer 5

α1: stimulates PLC, Ca ch. opens
α2: inhibits AC and Ca ch. opening, open K ch.
β1-3: activates AC, stimulates Ca ch. open

Question 6

What are the three types of receptors for serotonin?

Answer 6

5-HT1 and 2 metab.

5-HT3 ionotropic

Question 7

What do each of the receptors for serotonin do?

Answer 7

5-HT1: inhibits AC (opens K ch.)
5-HT2: stimulates PLC
5-HT3: open cation ch.

Question 8

What are the receptor types for glutamate? And what do they do?

Answer 8

KA, AMPA, and NMDA ionotropic

open Na/K or Na/K/Ca ch.

Question 9

What are the two types of receptors for GABA? What do they each do?

Answer 9

GABA-A ionotropic - open Cl ch.

GABA-B metabotropic - open K ch., inhibit Ca ch.

Question 10

What is the receptor for glycine? What is its function? With which other receptor does this function overlap?

Answer 10

1. glycine receptor ionotropic
2. open Cl ch.
3. GABA-A ionotropic

Question 11

What are the two types of receptors for ACh, and what kinds of receptors are these?

Answer 11

nicotinic (ionotropic)

muscarinic (metabotropic)