Neurovascular anatomy Flashcards

(1105 cards)

1
Q

oesophagus arterial supply

A

upper third - inferior thyroid artery
middle third - oesophageal branch of descending aorta
lower third - left gastric artery

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2
Q

oesophagus venous drainage

A

upper third - inferior thyroid
middle third - azygous
lower third - left gastric (portal) and azygous (systemic)

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3
Q

oesophagus LN

A

upper third - deep cervical
middle third - mediastinal
lower third - left gastric + celiac

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4
Q

oesophagus innervation

A

upper half - recurrent laryngeal
lower half - oesophageal plexus

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5
Q

stomach arterial supply

A

generally:

right gastric - branch of proper hepatic artery - branch of CHA
left gastric - branch of coeliac trunk
right gastro-omental - branch of gastroduodenal - branch of CHA
left gastro omental - branch of splenic - branch of coeliac trunk

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6
Q

branches of CHA

A

gastroduodenal artery
proper hepatic artery

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7
Q

arterial supply of lesser curvature

A

right and left gastric artery

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8
Q

arterial supply of greater curvature

A

right and left gastro-omental
short gastric arteries

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9
Q

stomach innervation

A

parasympathetic
sympathetic t6-t9

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10
Q

stomach lymphatic drainage

A

gastric LNs
gastro-omental LNs

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11
Q

L.O.S in rolling hiatus hernia

A

in place
requires surgery more than sliding HH

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12
Q

duodenum arterial supply

A

proximal to major duodenal papilla - gastroduodenal artery (celiac branch)
distal to major duodenal papilla - inferior pancreaticoduodenal artery (SMA)

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13
Q

duodenum lymph drainage

A

pancreaticoduodenal and superior mesenteric LNs

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14
Q

jejunoileal arterial supply

A

supermesenteric arteries - vasa recta

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15
Q

jejunoileal venous drainage

A

SMV

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16
Q

caecum:

arterial supply
venous drainage
innervation
LNs

A

A - ileocolic artery
V - ileocolic vein
N - superior mesenteric plexus
LNs - ileocolic LNs

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17
Q

jejunoileal lymph drainage

A

SM LNs

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18
Q

ascending colon:

arterial supply
venous drainage
innervation
LNs

A

A - ileocolic + right colic arteries
V - ileocolic + right colic arteries
lymph nodes: superior mesenteric LNs
N: superior mesenteric plexus

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19
Q

appendix:

arterial supply
venous drainage
innervation
LNs

A

A - appendicular artery
V - appendicular vein
N - superior mesenteric plexus
LNs - ileocolic LNs

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20
Q

ascending colon innervation

A

superior mesenteric plexus

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21
Q

midgut innervation

A

superior mesenteric plexus

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22
Q

hindgut innervation

A

inferior mesenteric plexus

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23
Q

inferior mesenteric plexus innervation

A

parasympathetic = pelvic splanchnic nerves
sympathetic = lumbar splanchnic nerves

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24
Q

transverse colon:

arterial supply
venous drainage
innervation
LNs

A

arterial supply: right, middle and left colic arteries
venous drainage: middle colic vein
innervation: proximal 2/3 = SMP, distal 1/3 = IMP
LNs: superior mesenteric

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25
descending colon: arterial supply venous drainage innervation LNs
A - left colic V - left colic Innervation - IMP LNs - Inferior mesenteric
26
SM + IM drain into....
cisterna chyla which drain into thoracic duct
27
seperator of right atria smooth vs rough walls
crista terminalis
28
what seperates conus arteriosus from inflow portion of RV
supraventricular crest
29
parietal pleura: innervation arterial supply
innervation: phrenic + intercostal nerves arterial supply - intercostal arteries
30
visceral pleura: innervation arterial supply
innervation - pulmonary plexus arterial supply - bronchial arteries
31
calot's triangle borders
superior - inferior border of liver medial - common hepatic duct lateral - cystic duct
32
what connects greater and lesser sacs
epiploic foramen (of Winslow)
33
cludocentesis
fluid from pouch of douglas for draining pelvic abcesses
34
trachea start and end point
c6 - t4/5
35
name the pleural recesses
costodiaphragmatic costomediastinal
36
parasympathetic effect on lungs (3)
bronchoconstriction vasodilation stimulate bronchial secretions
37
central tendon of diaphragm derived from ___?
septum transversum
38
each lung root contains...
bronchus bronchial vessels pulmonary artery pulmonary veins x2 pulmonary plexus lymphatic vessels
39
cx of fasciotomy
rhabdomyolysis
40
electrolyte disturbances causing digitalis toxicity
low magnesium low potassium high calcium
41
causes of low magnesium
diuretics TPN diarrhoea hypokalaemia hypocalcaemia alcohol
42
factors that decrease gastric acid production
secretin cholecystokinin somatostatin
43
phases of gastric secretion
1. cephalic - 30% 2. gastric - 60% 3. intestinal - 10%
44
trotter's triad
unilateral conductive HL ipsilateral facial pain and otalgia ipsilateral paralysis of soft palate
45
g cells produce
gastrin
46
what cells produce gastric acid
parietal cells
47
chief cells produce
pepsinogen
48
LP: - needle into? - where in spine?
into subarachnoid space around L3/L4
49
csf path
lateral ventricles 3rd ventricle cerebral aqueduct 4th ventricles SAS
50
Ormond's disease
fibrous proliferation of retroperitoneal structures pushes ureters medially causes HTN, kidney failure, lower back pain, DVT
51
case-control study good for...
rarer disease done when following group WITH outcome e.g. disease odds ratio
52
ix for assessing bladder reflex
MCUG
53
causes of raised anion gap
MUDPILES methanol uraemia dka paraldehyde iron lactic acidosis ethylene glycol salicylates
54
lacrimal gland innervation
opthalmic branch - lacrimal nerve greater petrosal nerve - secretomotor function
55
where are pectinate muscles in heart
RA
56
femoral canal borders
lateral - femoral vein medial - lacunar ligament anterior - inguinal ligament posterior - pectineal ligament
57
klippel-trenauney syndrome
port wine stains gigantism features varicosa veins spares saphenous veins
58
heart venous drainage
anterior cardiac veins - drain into RA coronary sinus: 1. great cardiac vein - along anterior interventricular groove 2. middle cardiac vein - along posterior interventricular groove 3. small cardiac vein - with marginal artery
59
IVC origin
L5
60
EARLY repolarisation of heart: ion responsible
potassium efflux
61
thymus: arterial supply venous drainage
A - anterior intercostal + branches of internal thoracic V - left brachiocephalic vein
62
breast: arterial supply venous drainage innervation
A: medial - internal thoracic. Lateral = mammary + lateral mammary (branches of AIC and PIC respectively) V: axillary + internal thoracic I: anterior + lateral cutaneous branches of the 4th-6th intercostal nerves
63
trachea A V N
A - inferior thyroid V - brachiocephalic, azygous, acessory hemizaygous N = recurrent laryngeal nerve
64
diaphragm A N
A = inferior phrenic N = phrenic n.
65
SVC tributaries
Brachiocephalic Azygous Mediastinal Pericardial Oesophageal
66
IVC tributaries
Hepatic Renal Lumbar Phrenic Gonadal
67
bronchi nerve supply
pulmonary branches of CN X
68
bronchioles specific cells
club cells - produce surfactant
69
alveoli cell lining
simple squamous
70
where do coronary arteries originate
aortic sinus
71
3 main causes of AS
1. age related calcification 2. congenital defects 3. RhF
72
what seperates arterial and venous vessels of heart
transverse pericardial sinus
73
4 functions of pericardium
1. fixes the heart 2. lubricartion 3. prevents overfilling 4. protection from infection
74
parasympathetic effect on heart
decrease HR
75
pericardium innervation
somatic innervation by phrenic nerve causes referred shoulder pain in pericarditis
76
tetralogy of fallot 4x
pulmonary stenosis (ESM) RVH VSD overriding aorta
77
2 parts of RA
sinus venosum (posterior) atria proper (anterior) - rough walled
78
level of pulmonary trunk bifurcation
t5/t6
79
bile leak post-cholecystectomy tx
ERCP+ sphincterotomy + CBD stent
80
cx after bypass
1. post-perfusion syndrome 2. MI 3. stroke 4. AKI
81
barret's oesophagus causes which cancer
adenocarcinoma of lower 1/3 oesophagus
82
zollinger ellison MEN subtype
type 1
83
graft for CABG
internal mammary artery
84
contents of popliteal fossa
popliteal artery popilteal vein common peroneal nerve tibial nerve small saph vein
85
hypertrophic vs keloid scar
keloid scar goes beyond original wound margins
86
osteomalacia bone profile
low calcium AND phosphate high ALP
87
hernia surgery differences in adults vs kids
adults - herniorrhhapy - fix abdomen weakness children - herniotomy
88
thoracic aorta origin and end
t4-t12
89
whats anterior to thoracic aorta
oesophagus left lung root pericardium
90
branches of thoracic aorta
bronchial posterior intercostal mediastinal oesophageal
91
brown-sequard syndrome sx
ipsilateral loss of proprioception + UMN signs contralateral loss of pain + temp sensation
92
verterbral lesions below ___ cause LMN sign
L1
93
what articulates with tubercle of ribs
tranverse process of vertebra
94
features of 1st rib
short and wider grooves due to subclavain vessels only 1 articular facet
95
what muscle has a relationship with 2nd rib
serratus anterior
96
what level do diaphragam crura arise
L1/L2
97
caval hiatus contents
IVC terminal branches of right phrenic nerve
98
oesophageal hiatus contents
oesophagus vagus nerve oesophageal branches of left gastric artery
99
aortic hiatus contents
thoracic aorta azygous vein thoracic duct
100
peripheral attachments of diaphragm
1. lumbar vertebrae 2. costal cartilages 7-10 3. xiphoid process
101
posterior diaphragm posterior border
t5-t12
102
phrenic nerve in relation to heart +hilum of lungs
anterior
103
right vagus nerve travel
runs parallel to trachea posterior to SVC and bronchus
104
left vagus nerve travel
anterior to aortic arch posterior to bronchus
105
SAAG>1.1
portal HTN
106
function of greater omentum
immunity - stops spread of infection
107
function of lesser omentum
holds organs together hepatogastric ligament hepatoduodenal ligament
108
embryology of peritoneum
parietal - somatic mesoderm visceral - splanchnic mesoderm
109
peritoneum cell type
simple squamous (mesothelium)
110
gubernaculum
fibrous cord attached to inferior portion of gonad and guides descent into scrotum or labia
111
why does appendix pain start umbilical
visceral peritoneal pain - poorly localised. midgut structure therefore pain in umbilical region once inflammation so great it reaches parietal layer - RIF localisation
112
mid inguinal point
halfway between PS + ASIS femoral pulse palpable here
113
inguinal canal borders
anterior -apneurosis of external obliques + reinforced by internal obliques floor - inguinal ligament + lacunar ligament medially roof - internal oblique + transversus abdominis + transversalis fascia posterior - tranversalis fascia
114
superficial ring: location formed by
superior to PT formed by external oblique invagination
115
contents of inguinal canal
spermatic cord OR round ligament ilioinguinal nerve genital branch of genitofemoral nerve
116
deep inguinal ring location
midpoint of the inguinal ligament ring created by tranversalis fascia
117
lumbar vertebra features
largest vertebral body VB is kidney shaped foramen is triangular spinous processes are short and broad transvers processes are long and thin
118
superficial fascia below skin in abdomen
above umbilicus - 1 layer below umbilicus - 2 layers superior - campers inferior - scarpas
119
external oblique muscles origin and insertion action innervation
iliac crest + PT to ribs 5-12 contralateral rotation of torso thoracoabdominal nerve (t7-11), subcostal nerve (t12)
120
internal oblique muscles origin and insertion action innervation
iliac crest + inguinal ligament to ribs 10-12 ipsilateral rotation of torso thoracoabdominal nerve (t7-11), subcostal nerve (t12), branches of lumbar plexus
121
transversus abdominis origin and insertion action innervation
xiphoid + linea alba + costal cartilage 7-12 to inguinal ligament compression of abdominal wall thoracoabdominal nerve (t7-11), subcostal nerve (t12), branches of lumbar plexus
122
rectus abdominis origin and insertion action innervation
innervation = TAN pubic crest to xiphoid and 5th-7th costal cartilages
123
pyramidalis innervation
SCN
124
pyramidalis insertion and origin
xiphoid/CC 5-7 to pubic crest
125
transpyloric plane
L1 halfway between jugular notch and pubic symphysis
126
quadratus lumborum origin and insertion action innervation
transverse process of L1-L4 to iliac crest extension and lateral flexion of verterbal column + fixing of 12th rib during inspiration innervation T12-l4
127
psoas major origin and insertion action innervation
vetebral bodies of T12-l5 inserts onton lesser trochanter of femur hip flexion anterior rami of L1-L3
128
psoas minor origin and insertion action innervation
only 60% have a psoas minor vertebral bodies of T12-L1 onto pectineal line hip flexion anterior rami of L1
129
Iliacus origin and insertion action innervation
iliac fossa to LToF flexion of hip femoral nerve (L2-L4)
130
why is psoas sign +ve in appendicitis
contracting iliopsoas comes into contact with inflammed appenidx
131
lower leg anterior compartment: muscles actions of muscles nerve supply
extensor hallucis longus + extensor of toes anterior tibialis - dorsiflexor peroneus tertius - dorsiflexor extensor digitorum longus - dorsiflexor + extensor of toes deep peroneal nerve
132
lower leg peroneal compartment: muscles actions of muscles nerve supply
peroneus longus - everts foot + plantarflexor peroneus brevis - plantarflexor superficial peroneal nerve
133
lower leg posterior superficial compartment: muscles actions of muscles nerve supply
gastrocnemius - plantar flexor + may also flex the knee soleus - plantarflexor tibial nerve
134
lower leg posterior deep compartment: muscles actions of muscles nerve supply
flexor hallucis longus - flex toes flexor digitorum longus - flex toes tibialis posterior - plantarflexor + foot inverter tibial nerve
135
palmar interossei function
adductors of fingers
136
dorsal interossei function
abduction of fingers
137
lumbricals function
flex @ MCPJ extend @ IPJ
138
lumbricals innervation
1+2 = median 3+4 = ulnar
139
thenar eminence muscles
opponens policis abductor policis brevis flexor policis brevis
140
hypothenar eminence muscles
opponens digiti minimi flexor digiti minimi abductor digiti minimi
141
most common organism of Nec Fasc
streptococcus
142
most common causative organism for fourniers gangrene
e.coli + bacteriodes
143
extravasation injuries = tx
doxorubicin - cold compress TPN - hyaluronidase
144
fissure in ano 1st line tx
gtn or diltiazem cream
145
internal haemorrhoids 1st line tx
ligation > sclerotherapy
146
ankle joint ligaments
medial - deltoid ligaments lateral - anterior talofibular, posterior talofibular, calcaneofibular
147
ankle fracture mx based on weber
A - boot B - boot or surgery - depends on talar shift C - fixation
148
lauge-hansen classification
supination adduction supination external rotation pronation abduction pronation external rotation
149
syndesmosis made of
interosseus membrane anterior tibiofibular ligament posterior tibiofibular ligament transverse tibiofibular ligament
150
heparin affects which clotting factors
2,7,9, 10, 11
151
bevacuzimab has a role in which cancers
colorectal renal glioblastoma
152
undisplaced intracapsular fracture tx
internal fixation hemiarthroplasty if unfit
153
stable intertrochanteric fracture tx
DHS
154
abdominal aorta branches
inferior phrenic t12 coeliac trunk t12 superior mesenteric l1 suprarenal l1 renal l1 testicular l2 lumbar l1-l2 inferior mesenteric l3 medial sacral l4
155
le fort 2 vs le fort 3 difference
more likely csf leak in le fort 3
156
ileum resection cx
diarrhoea risk of gallstones due to malabsorption of bile salts tx with oral cholestyramine
157
klumpke features
claw hand - mcpj extension, iph flexion horners loss of sensation over medial forearm and hand loss of wrist flexors
158
oesophagus constricts at 4 points
aortic arch left main bronchus cricoid cartilage diaphragmatic hiatus
159
layers of oesophagus
adventitia muscle layer submucosa mucosa
160
oesophagus vertebral level start and end
c6 to t11
161
difference between upper oesophageal and lower oesophageal sphincter
upper is muscular - cricopharyngeus muscle lower is physiological
162
organs anterior to stomach
liver gall bladder
163
superior duodenum level
L1
164
descending duodenum level
L1-L3
165
inferior duodenum level
lateralises left L3
166
ascending duodenum level
L3-L2
167
superior duodenum special facts (3)
1. connected to liver by hepatoduodenal ligament 2. most common site of duodenal ulceration 3. only intraperitoneal portion of duodenum
168
causes of appendicitis
<30 years old - lymphatic tissue >30 years old - faecolith
169
features of large colon
taenia coli omental appendices wider than small intestine
170
rectum begins at which vertebral level
s3
171
2 main flexures in rectum
sacral flecure anorectal flexure - formed by puborectalis muscle
172
site in rectum that temporarily stores faeces
ampulla
173
is the rectum covered by peritoneum
partially upper third is middle third is covered anteriorly lower third is not
174
rectal arterial supply
superior rectal artery - inferior mesenteric artery middle rectal artery - internal iliac artery inferior rectal artery - internal pudenal artery
175
rectal veins
superior rectal vein - into portal circulation middle and inferior rectal veins - into systemic circulation anastomosis in wall of anal canal between both circulations
176
rectal innervation
sympathetic 1. lumbar splanchnic n 2. superior hypogastric plexus 3. inferior hypogastric plexus parasympathetic 1. s2-s4 via pelvic splanchnic n
177
rectal lymph node drainage
upper rectum - pararectal LNs lower rectum - internal iliac LNs
178
anal canal sphincters
internal sphincter - surrounds upper 2/3 involuntary smooth muscle external sphincter - surrounds lower 2/3 voluntary
179
junction between rectum and anal canal
anorectal ring
180
anorectal ring formed of
fusion between internal and external anal sphincters and puborectalis muscle
181
dentate line formed by
anal canals
182
cell differences above and below dentate
above - columnar below - non-keratinised stratified squamous once at the intersphincteric groove - becomes keratinised stratified squamous
183
above dentate line arterial supply venous drainage innervation lymph
A - superior rectal artery + branches of middle rectal artery V: superior rectal vein (portal) N: inferior hypogastric lymph: internal iliac nodes
184
below dentate line arterial supply venous drainage innervation lymph
A: inferior rectal artery + branches of middle rectal V: inferior rectal vein N: inferior rectal nerve LN: superficial inguinal
185
shape of each adrenal gland
right - pyramidal left - semilunar
186
adrenal arterial supply
1. superior adrenal - branch of internal phrenic 2. middle adrenal 3. inferior adrenal - branch of renal arteries
187
adrenal venous drainage
right adrenal vein drains straight into IVC left adrenal vein drains into left renal vein then into IVC
188
adrenal innervation
coeliac plexus greater splanchnic nerves
189
adrenal lymphatic drainage
lumbar LNs
190
parotid tumours only affect facial nerve if
malignant
191
most common bilateral tumour of parotids
warthins
192
cord of brachial plexus related to
axillary artery
193
dose of protamine before vascular bypass surgeries
around 3000 U given 3-5 mins before clamping of vessel
194
dose of protamine before cardiac bypass surgeries
30000 U
195
macrolide MOA
inhibit protein synthesis by binding to 50S
196
aminoglycoside MOA
inhibit protein synthesis
197
most common biliary disease in HIV patients
sclerosing cholangitis
198
where is ampulla of vater
medial aspect in the 2nd part of duodenum
199
ligament of treitz significance
AKA suspensory muscle of duodenum differentiates Upper vs Lower GI bleed
200
ejection systolic murmur causes
AS Aortic sclerosis pulmonary stenosis ToF HOCM ASD
201
mid diastolic murmur causes
mitral stenosis austin flint (severe AR)
202
late systolic murmur causes
mitral valve prolapse coarctation of aorta
203
decreased global uptake on technetium scan
Subacute thyroiditis
204
trigeminal nerve originates from ___
pons
205
muscles innervated by mandibular nerve
maasseter temporalis tensor tympani mylohyoid pterygoid anterior belly of digastric
206
gingiva innervated by which nerve
lingual nerve
207
periosteum layers
outer fibrous layer inner cambium layer - contains progenitor cells
208
pharyngeal arches: 1st
external carotid mandibular n
209
pharyngeal arches: 2nd
facial nerve
210
pharyngeal arches: 3rd
common carotid internal carotid glossopharyngeal inferior parathyroids thymus
211
pharyngeal arches: 4th
right subclavian aortic arch vagus superior parathyroid
212
pharyngeal arches 6th
pulmonary arteries vagus + RLN ductus arteriosus
213
hashimotos histology
lymphocytic infiltration + fibrosis
214
penile fractures pathophysiology
break in the tunica albunginea
215
ansa cervicalis nerve roots
c1-c3
216
thoracic cord lesion symptoms
ACUTE: spinal shock causes arreflexia + flaccid paralysis AFTER WEEKS: - spastic paralysis - sensory ataxia - urinary incontinence - hyperreflexia - extensor plantars
217
forearm flexor muscles
flexor carpi radialis - median nerve flexor carpi ulnaris - ulnar palmaris longus - median flexor digitorum superificialis - median flexor digitorum profundus - ulnar (medial) + anterior interosseus (lateral)
218
flexor carpi radialis functions
wrist flexor carpal abductor part flexor of elbow part pronater of forearm
219
flexto carpi ulnaris functions
wrist flexor carpal adductor
220
breast surgery cx
intercostobrachial nerve injury - paraesthesia of armpit long thoracic nerve injury serosa
221
kidneys anatomical position wrt vertebra
T12-L3
222
order of encapsulating layers of kidneys
outer to inner pararenal fat renal fascia perirenal fat renal capsule
223
function of calyx in kidneys
store urine
224
what can be used to show differing arterial supply to parts of kidney
Line of Brodel
225
describe pathway: renal artery to efferent arterioles
renal artery TO anterior or posterior renal artery TO 5x segmental arteries each TO interlobar arteries TO arcuate arteries TO interlobular arteries TO afferent arterioles TO glomerulus TO efferent arterioles
226
what type of vessels make up glomerulus
capillaries
227
kidney lymphatic drainage
para-aortic nodes
228
horseshoe kidney
fusing of both kidneys fuse at the isthmus (lower pole)
229
why can renal cancers often be treated with partial nephrectomies
segmental blood supply
230
how is spleen connected to other organs
greater ommentum gastrosplenic ligament splenorenal ligament
231
spleen anterior to...
left ribs left diaphragm left lung
232
spleen arterial supply
splenic artery
233
spleen venous drainage: portal or systemic?
splenic vein > SMA > hepatic portal vein
234
spleen innervation
coeliac plexus
235
spleen LN
pancreaticosplenic LNs
236
vertebral level of pancreas
L1
237
pancreas relationship to duodenum
2nd part of duodenum wraps around pancreatic head
238
what is posterior to head of pancreas
aorta IVC
239
which part of the pancreas is intraperitoneal
tail - in the splenorenal ligament
240
pancreas blood supply
pancreatic branches of splenic artery pancreatic head: + superior pancreaticoduodenal artery (coeliac)+ inferior pancreaticoduodenal artery (SMA)
241
pancreas LN
pancreaticoduodenal LN
242
pancreas venous drainage
head - SMV rest - pancreatic veins of splenic vein
243
pancreatitis causes
GET SMASHED gallstones ethanol trauma scorpion mumps autoimmune steriods high calcium, high triglycerides, high PTH ERCP drugs e.g. sodium valproate, azathioprine
244
what stimulates relase of bile from gall bladder
cholecystokinin
245
Hartmann's pouch
mucosal folds at neck of the gall bladder - commonest entrapment of gallstones
246
common hepatic duct runs ____ in relation to pancreas head + 1st part of duodenum
posterior
247
cystic artery is a branch of
right hepatic artery
248
gall bladder venous drainage
neck - into cystic vein body + fundus - directly into hepatic sinusoids
249
gall bladder innervation
sympathetic - coeliac plexus parasympathetic - vagus
250
parasympathetic innervation effect on gall bladder
stimulate contractions
251
lymph nodes of gall bladder
hepatic lymph nodes
252
where do hepatic lymph nodes drain into
coeliac lymph nodes
253
ligaments of liver
1. falciform ligament - straps liver to anterior abdomen wall 2. ligamentum teres - in free edge of falciform ligament 3. coronary ligament - attach bare edge of liver to diaphragm 4. triangular ligament - liver to diaphragm + LESSER OMENTUM (hepatogastric + hepatoduodenal ligaments)
254
Morison's pouch: 1. what is it 2. clinical relevancee
1. potential space between liver and right kidney. deepest part of peritoneal cavity when lying flat 2. ascites more likely to accumulate here in bed-ridden patient
255
liver is covered by a fibrous layer named?
Glisson's capsule
256
lobes of liver
right left caudate quadrate
257
what seperates caudate and quadrate lobes of liver
porta hepatis
258
portal triad
hepatic artery portal vein hepatic bile duct
259
liver blood supply
hepatic artery proper - 25% portal vein - 75%
260
liver innervation
sympathetic - hepatic plexus parasympathetic - vagus
261
liver lymph drainage
anterior - hepatic LNs posterior - phrenic + posterior mediastinal LNs
262
thoracic aorta branches UPDATED
bronchial mediastinal pericardial oesophageal intercostal superior phrenic
263
how can aortic aneurysm affect voice
irritates recurrent laryngeal nerve causing hoarse voice
264
watershed zone
splenic flexure
265
coeliac trunk compression by
median arcuate ligament
266
most common type of visceral aneurysm
splenic aneurysm
267
disc herniation pathophysiology
jelly nucleus pulposus herniates through annulus fibrosus
268
cervical vertebrae features
7x bifid spinous processes triangular vertebral foramine have transverse foramina
269
thoracic verterbrae features
12x circular foramine vertebral bodies have 2x demifacets transverse processes have costal facets spinous processes are inferiorly orientated
270
lumbar vertebra features
5x largest vertebral bodies kidney shaped VB triangular vertebral foramina SP short and wide TP long and thin
271
sacrum features
5x fused vertebrae inverted triangle shaped have lateral facets for ilium
272
coccyx features
4x fused verterbrae no vertebral arches
273
lumbarisation
S1 seperation from sacrum
274
sacralisation
L5 fused to sacrum
275
trochlear nerve supplies this ocular muscle
superior oblique
276
corneal reflex innervation
afferent - nasociliary branch of ophthalmic (V1) efferent - facial nerve via oribicularis oculi muscle
277
where does trigeminal nerve originate
pons
278
where does facial nerve originate
between pons and medulla
279
where does vestibulocochlear nerve originate
pons
280
where does glossopharyngeal nerve originate
pons
281
where does vagus nerve originate
medulla
282
where does hypoglossal nerve originate
medulla
283
which tongue muscle does hypoglossal nerve not innervate
palatoglossus
284
course of facial nerve
leave between pons and medulla passes temporal bone and enters internal auditory meatus then passes through facial canal and exits at the stylomastoid foramen
285
what cranial nerve supplies parotid
glossopharyngeal
286
richter's hernia
wall of small bowel (usually anti-mesenteric layer) is strangulated - but as luminal patency maintained there is no obstruction
287
bochdalek hernia
congenital hernia nearly always associated with left hemidiaphragm causes lung hypoplasia more common in males
288
jenkins rule
aim to minimis incisional hernias in midline laparotomy incisions suture length 4x incision length sutures at 1cm intervals sutures 1cm from wound edge
289
morgagni hernia
rare diaphgramatic hernia hernia through foramen of morgagni
290
umbilicus hernia tx
surgery after 3rd birthday
291
paraumbilical hernias more common in ?
adult females
292
technique for paraumbilical hernia repair
mayo's repair - overlapping vertical edges
293
spigelian hernias
lateral to rectus abdominis where arcuate line meets semilunaris line
294
middle meningeal artery is a branch of
maxillary artery which is a branch of external carotid artery
295
HLA types asx with mismatch
A B C DR
296
septic arthritis most common causative organism
staph aureus
297
basilic vein medial or lateral? superficial or deep?
medial superficial until mid upper arm
298
middle meningeal artery exits through which cranial foramen
foramen spinosum
299
basilic vein + ____ vein > _____ vein
medial brachial vein axillary vein
300
potent vasodilators in acute inflammation
prostaglandins nitric oxide histamine complement 5a and 3a lysosomal compounds
301
serotonin - vasodilator or vasoconstrictor?
depends on vessel state - in healthy vessels it is a vessel dilator
302
malignancy histology
angiogenesis increased mitoses de-differentiation invasion of basement membrane - this differentiates it to in situ tumours
303
types of gastritis
type A - autoimmune type B - antral (infective erosive - NSAIDs and alcohol stress - mucosal ischaemia reflux - bile refluxes into stomach. prokinetics can help
304
type A gastritis pathophysiology
autoimmune antibodies to parietal cells causing decrease HCl and decreased intrinsic factor decrease in HCl also stimulates gastrin release and stimulates enterochromaffin cells leading to adenoma production
305
causes of lymphodema
primary - congenital - milroys secondary - infection e.g. filariasis - DVT - thrombophlebitis - radiation to LNs - LN clearance - lymphatic malignancy
306
indications for lymphoedema surgery
marked disability and/or deformity incompetent proximal lymphatics
307
lymphoedema procedures
Homans - reduction procedure with preservation of overlying skin Charles - all skin and subcutaneous tissue removed + split skin grafts placed over surgical sites lymphovenous anastomosis - when proximal lymph obstruction with normal distal lymphatics
308
stored blood has more or less affinity for oxygen
more affinity less 2,3-DPG
309
haldane effect of haemoglobin
LEFT SHIFT haem has greater affinity for oxygen
310
what causes haldane effect
low co2 low 2,3-DPG HbF carboxyhaemoglobin low temperature
311
bohr effect of haemoglobin
RIGHT SHIFT haem has lower affinity for oxygen oxygen more readily available/deliverable
312
what causes bohr effect
acidosis high co2 high temperature high 2,3-DPG
313
suxamethonium features
depolarising muscular blocker rapid onset produces muscular contractions before paralysis
314
side effects of suxamethonium
hyperkalaemia malignant hyperthermis
315
atracurium reversing agent
neostigmine
316
diagnostic OGD prep
NBM >6hrs
317
flexi sigmoidoscopy prep
phosphate enema 30 mins before
318
femoral triangle borders
medial - adductor longus lateral - sartorius superior - inguinal ligament
319
brachial embolectomy can damage which nerve
median @ ACF
320
malignant mesothelioma rough tx
receptive to combination chemotherapy - usually cisplatin based relatively resistant to radiotherapy - best given pre-operatively
321
fem-pop surgery
for proximal occlusions use own vein if sufficient if not, can use PTFE + Miller cuff e.g. in varicose veins
322
propofol features
rapid onset pain on injection anti-emetic properties
323
sodium thiopentane features
very rapid onset marked myocardial depression
324
etomidate
can cause adrenal suppression
325
Laplace law
wall tension proportional to pressure x radius - explains why its harder to blow up a balloon at the start
326
how does Laplace law explain why aneurysms don't ordinarily explode
pressure is inversely proportional to radius as balloon inflates, pressure decreases
327
bainbridge reflex
reflexive increase in heart rate when baroreceptors in atria are stimulated this decreases SVC pressure, creating a pressure gradient between venous system and right atria - meaning no pooling of blood in venous system can occur in rapid blood transfusions
328
sympathetic effect on ventricles
increase contracrility via increase of intracellular calcium
329
what increases functional residudal capacity
standing up right asthma emphysema
330
what decreases FRC
abdo swelling pulmonary oedema decreased diaphragm tone
331
cavernous sinus lateral wall contents
oculomotor trochlear ophthalmic maxillary
332
cavernous sinus contents
ICA (medially) abducens (laterally)
333
insulinoma ix and tx
ix - endoscopic USS tx - benign = enucleation, malignant = whipples
334
superficial back muscles
lats traps rhomboid minor rhomboid major levator scapula
335
traps: origin and insertion innervation
origin: skull + spinous process C7-T12 insertion: clavicle, acromion, scapula spine
336
lats: origin and insertion innervation
origin: spinous process of T6-T12 insertion: intertubercular sulcus of humerus innervation: thoracodorsal nerve
337
function of lats
extends, adducts and medially rotates upper arm
338
levator scapula: origin and insertion innervation
transverse process of C1-C4 insertion: medial border of scapula dorsal scapular nerve
339
function of levator scapula
elevate scapula
340
rhomboid major: origin and insertion innervation
spinous process of T2-T5 medial border of scapula dorsal scapular nerve
341
rhomboid minor origin and insertion innervation
spinour process of C7-T1 medial border of scapula dorsal scapular nerve
342
intermediate muscles of the back
serratus posterior superior serratus posterior inferior
343
serratus posterior superior origin and insertion innervation
C7-T3 to anterior ribs 2-5 intercostal nerve
344
serratus posterior superior action
elevate the ribs 2-5
345
superficial muscles of the deep back muscles
the SPINOTRANSVERSALIS muscles splenius capitis splenius cervicis
346
splenic capitis innervation
posterior rami of c3-c4
347
splenic capitis funciton
rotate + extend head
348
intermediate muscles of the deep back muscles
erector spinae muscles longissimus iliocostalis spinalis
349
function of erector spinae muscles
unilateral contraction = lateral flex bilateral contraction = extension
350
innervation of erector spinae muscles
posterior rami of the spinal nerves
351
deep muscles of the deep back
transversospinales muscle group semispinalis - extends head multifidius rotatores
352
conus medullaris
tapering of spinal cord @ L1/L2
353
spinal cord enlarges where
cervical and lumbosacral regions
354
2 depressions of spinal cord
anterior median fissure posterior median sulcus
355
filum terminales
meninges ending at bottom of spinal cord
356
epineurium
dura mater surrounding the peripheral nerves when they leave spinal cord
357
spinal cord vasculature
anterior spinal artery - branch of vertebral arteries posterior spinal artery - branch of vertebral artery or PICA
358
artery of Adamkiewicz
main artery that supplies blood to the lower third of the spinal cord
359
venous drainage of spinal cord
3x anterior spinal veins 3x posterior spinal veins
360
where does subscapularis attach on scapula
subscapular fossa on costal surface of scapula
361
where do supraspinatus and infraspinatus originate
posterior side of scapula supraspinatus fossa infraspinatus fossa
362
where does long head of biceps brachii attach
supraglenoid tubercle
363
where does long head of triceps brachii attach
infraglenoid tubercle
364
most common part of clavicel that is fractured
middle
365
muscles inserting onto greater tuberosity of humerus
supraspinatus infraspinatus teres minor
366
muscles inserting onto lesser tuberosity of humerus
subscapularis
367
muscles attaching onto intertubercular sulcus of humerus
lats pec major teres major
368
what tendon runs along intertubercular sulcus
long head of biceps brachii
369
what neurovascular vessels are related to surgical neck of humerus
axillary nerve circumflex humeral vessels
370
axillary nerve injury paralyses which muscle
deltoid teres minor ABDCUTORS
371
what muscles attach onto humeral shaft
coracobrachialis deltoid (tuberosity) brachialis brachoradialis medial and lateral tricep heads
372
mid shaft humeral fracture affects which nerves
radial nerve - wrist drop
373
lateral epicondyle is associated with which attachment site of humerus
trochlea
374
medial epicondyle is associated with which attachment site of humerus
capitulum
375
what makes up trochlear notch of ulnar
olecranon + coronoid fossa
376
which artery is at risk in supracondylar humeral fractures
brachial artery
377
volkmann's contracture
ischaemic contracture as a result of brachial artery damage causing fibrosis and shortening of flexors of hand and wrist
378
how do you test function of anterior interosseoss nerve
OK sign assessing flexor pollicis longus
379
ulnar shaft shape
triangular shape
380
monteggia fracture
proximal ulnar fracture with radial head dislocation at elbow
381
galeazzi fracture
distal radial fracture with distal RUJ dislocation
382
what muscle inserts on to radial tuberosity
biceps brachii
383
proximal carpal bones (lateral to medial)
scaphoid,lunate, triquetrum, pisiform
384
distal carpal bones (lateral to medial)
trapezium, trapezioid, capitate, hamate
385
bennetts fracture
base of 1st metacarpal fracture
386
tx of fibroadenoma
<3cm - observation >4xm - cone biopsy to exclude phyllodes
387
as well as resection, what are colon cancer patients with high chance of recurrence offered
chemotherapy - 5FU + oxaliplatin combination
388
rectal cancer: anterior resection or APER?
APER is sphincters involved or lower tumours (anal verge)
389
difference between tx of rectal cancers and colon cancers
rectum is retroperitoneal therefore neoadjuvant radiotherapy can be used
390
which colon cancers need chemotherapy
high risk recurrence lymph node involvement
391
transverse colon cancer tx
extended RHC + ileocolic anastomosis
392
left colon cancer tx
LHC + colon-colon anastomosis
393
sigmoid cancer tx
high anterior resection with colo-rectal anastomosis
394
upper rectum tx
anterior resection (TME) with colo-rectal anastomosis
395
low rectum tx
anterior resection (low TME) with colo-rectal anastomosis +/- defunctioning stoma
396
why do rectal cancers usually need defunctioning stoma
to reduce the risk of anastomotic leakage and reoperation rates
397
most common type of rotator cuff tear
supraspinatus
398
gastric cancer tx
if >5-10cm from GOJ = subtotal resection if <5cm from GOJ = total gastrectomy + Roux en Y bypass will need lymphadenectomy and most patients get pre- or post-op chemo
399
investigation for suspected lymphoma presenting with lymphadenopathy
excision biopsy
400
axillary artery branches
Highest thoracic Thoraco-abdominal Lateral thoracic Subscapular - circumflex scapula artery is a branch of this Posterior circumflex humeral artery Anterior circumflex humeral artery he took love so pain awaits
401
how does cholestatic jaundice cause vit k deficiency
less bile into circulation vit K cannot be absorbed as well
402
what muscle flexes DIP joints
flexor digitorum profundus
403
TPN SEs
phlebitic can cause deranged LFTs long term
404
testicular cancer tx
orchidectomy via inguinal approach
405
gardners syndrome facts
Autosomal dominant can cause malignant tumours of colon APC gene association to desmoid tumours
406
cervical ribs usually arise from which vertebra
C7
407
layers of spermatic cord
inner - transversalis fascia outer - external oblique
408
contents of spermatic cord
vas deferens vas deferens artery testicular artery genital branch of genitofemoral nerve cremasteric artery pampiniform plexus SNS fibres lymphatic vessels
409
which cancer surgeries need bowel prep
left sided colon
410
in surgeries with radiated tissue - how do you close wounds
using flaps
411
which heparin for bypass
unfractioned - shorter HL, more controllable
412
c fibres trasmit ...
mechanicothermal stimuli
413
A beta fibres transmit
touch and pressure stimuli
414
B fibres transmit
autonomic stimuli
415
CSF contains ???
no RBC less glucose than plasma
416
hyatid cysts associated with which infection
echnicoccus infection
417
USS shows daughter cysts with septa and thick walls in liver??
hyatid cysts
418
how does pagets disease cause high output heart failure
angiogenesis
419
path of subclavian artery and vein
both pass OVER (anterior) 1st rib but POSTERIOR to clavicle SCA passes posterior to scalenus anterior SCV passes anterior to scalenus anterior
420
trunks of brachial plexus relationship to SCA
brachial plexus passes posterior to SCA at 1st rib
421
3 types of nerve injury
neuropraxia axonotmesis neurotmesis
422
neuropraxia features
nerve intact problem with conduction wallerian degeneration not present
423
axonotmesis features
axon damaged but connective tissue intact wallerian degeneration occurs
424
wallerian degeneration
distal axonal injury
425
neurotmesis features
degeneration of axon and myeline sheath wallerian degeneration occurs
426
ulnar nerve path in forearm
medial forearm passes inferiorly to flexor carpi ulnaris
427
scrotal cancer drains into which lymph nodes
inguinal LNs
428
access point for right middle lobe
6th ICS in mid axillary line
429
quadrangular space borders
superior - inferior border of teres minor inferior - superior border of teres major medial - lateral border of triceps brachii lateral - surgical neck of humerus
430
quadrangular space contents
axillary nerve posterior circumflex humeral artery
431
triangular space borders
superior - inferior border of teres minor inferior - superior aspect of teres major lateral - medial margin of long head of triceps brachii
432
triangular space contents
circumflex scapular artery
433
triangular interval borders
superior border - inferior border of teres major lateral - lateral head of triceps medial - long head of triceps trachi
434
triangular interval contents
radial nerve profunda brachii artery
435
axilla borders
anterior - pec major + minor posterior - scapula, teres major, + lats medial - serratus anterior + thoracic wall lateral - intertubercular sulcus
436
what affects axilla size
arm abduction - decreases it
437
apex of the axilla
lateral border of 1st rib posterior border of clavicle superior border of scapula
438
contents of axilla
axillary artery axillary vein brachial plexus axillary lymph nodes biceps brachii short head
439
cubital fossa borders
superior - epicondylar line medial - lateral border of pronator teres lateral - medial border of brachoradialis
440
cubital fossa contents (5)
radial nerve median nerve brachial artery biceps tendon median cubital vein
441
carpal tunnel contents
median nerve 1x flexor pollicis longus tendon 4x flexor digitorum supericialis 4x flexor digitorum profundus
442
median nerve branches
splits in carpal tunnel recurrent branch - thenar muscles palmar digital nerve - innervates lateral lumbricals + sensation
443
anatomical snuffbox contents (3)
radial artery superficial branch of radial nerve cephalic vein
444
anatomical snuffbox borders
medial - extensor hallucis longus lateral - extensor pollicis brevis proximal border = styloid process of radius
445
extensor compartment 1 of wrist contents
Extensor pollicis breivs abductor pollicis longus
446
extensor compartment 2 of wrist contents
extensor carpi radialis longus extensor carpi radialis brevis
447
extensor compartment 3 of wrist contents
extensor policis longus
448
what seperates extensory compartment 2 and 3 of the wrist
Lister's tubercle of radius
449
ulnar's canal contents
ulnar nerve ulnar artery venae comitantes of ulnar artery lymphatic vessels
450
dysphagia lusoria is dysphagia caused by what
oesophageal compression from vascular abnormality
451
dysphagia lusoria dx ix
CT angio
452
sural nerve supplies sensation to which area
lateral aspect of foot
453
dorsum of foot sensation nerve
superficial peroneal nerve
454
1st web space of foot sensation nerve
deep peroneal nerve
455
cell saver devices what is it contraindications
collect patient blood during surgery and reinfuse CI: malignancy and infection
456
Lynch disease cancer associations
colorectal endometrial
457
Lynch disease gene
mismatch repair gene mutation
458
ESWL contraindications
pregnancy patients with severe calcification of vessels
459
uteroscopy method
scope through urethra and bladder into ureters laser of pneumatic fragmentation a stent can be left in situ
460
RENAL stone tx
0-5mm + asx = observation <10 = ESWL 10-20 = ESWL or ureteroscopy >20 = PC NL
461
URETERIC stone tx
0-5mm = observation 5-10mm = ESWL 10-20mm = ureteroscopy
462
oesophageal cancer tx
largely resction based no resection if patient has mets or N2+ disease lower or middle third - Ivor lewis oesophagectomy upper third - Mckeowans (total) very distal tumours - can have transhiatal procedures
463
ivor lewis incisions
laparotomy + RHS thoractomy (Mckeowan = + neck incision)
464
how can delayed gastric emptying be avoided in oesophagectomies
pyloroplasty - widening of canal
465
anal fissures associations
STDs IBD leukaemia TB previous surgery
466
catecholamines derived from ....
tyrosine (--> dopamine --> NA -->A)
467
which clotting factors are most sensitive to temperature
FACTOR 5 AND 8 this is why FFP needs to be frozen ASAP
468
gluteus maximus innervation
inferior gluteal nerve
469
bartons fracture
distal radial fracture + radiocarpal dislocation
470
holstein lewis fracture
distal 1/3 humerus fracture causing entrapped radial nerve
471
varicose veins tx
1. endothermal ablation 2. foam sclerotherapy 3. trendelnberg surgery
472
cowden disease what is it mutation ?
PTEN mutation harmatomal growths of colon also associated with breast cancer
473
boerhaave syndrome ix
CT contrast
474
boerhaave syndrome tx
<12hours since sx onset = surgery >12 hours = controlled fistula with T tube
475
positive iontropes
adrenaline/noradrenaline dopamine glucagon dobutamine theophylline
476
alpha 1 receptors MOA
vasoconstriction
477
alpha 2 receptors MOA
vasoconstriction
478
beta 1 receptors MOA
increase heart rate and contractility
479
beta 2 receptors MOA
vasodilation
480
adrenaline MOA
alpha 1, alpha 2, beta 1, beta 2 stimulation
481
noradrenaline MOA
alpha 1 stimulation
482
dobutamine MOA
beta 1 stim (increase contractility + heart rate)
483
omphalitis definition, organism + tx
infection of umbilicius staph aureus topical + systemic abx
484
umbilical granuloma
cherry red lesions
485
patent urachus - definition and symptoms
patent connection between umbilicus and bladder sx - urine leaks through umbilicus
486
biers block
double torniquet applied prilocaine injected into vein
487
which local anaesthetic is very cardiotoxic
bupivicaine
488
why is adrenaline sometimes added to local anaesthetic
potentiates duration of action
489
penile erection physiology
1. autonomic innervation: - SNS from T11-L2 and PSNS from S2-S4 - PSNS - causes erection - SNS - causes ejaculation 2. somatic - dorsal penile nerve - pudendal nerve
490
ulnar nerve and artery association
nerve lies on ulnar side of artery
491
2 nerves involved in voice production
superior laryngeal nerve recurrent laryngeal nerve
492
superior laryngeal nerve innervates ... ?
cricothyroid muscle - tenses vocal cords
493
paralysis of superior laryngeal nerve causes
pitch abnormalities
494
specificity =
true negative / true negative + false positives
495
laryngeal muscles and their function (4)
posterior cricoarytenoid - abduct vocal folds lateral cricoartyenoid - adduct vocal folds thyroarytenoid - relaxes vocal cords vocalis - relaxes posterior fold, tenses anterior folds
496
laryngeal muscles supplied by
laryngeal arteries branch of superior/inferior thyroid arteries branch of ECA
497
cranial nerve for external ear sensation
auriculotemporal nerve branch of mandibular nerve
498
which nerve runs next to middle meningeal artery
auriculotemporal nerve
499
allograft
same species
500
pec majo function
adduct and medially rotate upper arm
501
pec major innervation
medial and lateral pectoral nerves
502
what is the added function of clavicular head of pec major
flex upper limb
503
pec major insertions
clavicular head: medial clavicle sternal head: sternum + 1-6th CC both attach on intertubercular sulcus of the humerus
504
pec minor function
stabilise scapula
505
pec minor innervation
medial pectoral nerve
506
pec minor insertions
ribs 3-5 onto coracoid process of scapula
507
serratus anterior function
rotates scapula allowing for shoulder flexing >90 degrees
508
serratus anterior insertions
lateral aspect of ribs 1-8 and insert onto scapula
509
subclavius action innervation
depress clavicle nerve to subclavius
510
biceps brachii origin and insertion
long head - supraglenoid tubercle short head - coracoid process insert onto radial tuberosity
511
what artery supplies anterior compartment of upper arm
brachial artery
512
coracobrachialis insertions
coracoid process to medial shaft humerus
513
coracobrachialis function
shoulder flexion
514
brachialis insertions
humeral shaft to unlar tuberosity
515
triceps supplied by which blood vessel
profunda brachii
516
where do triceps insert onto
olecranon
517
deltoid insertions
lateral 1/3 clavicle onto deltoid tuberosity
518
front delt function
flexion and internal rotation
519
rear delt fx
extension and external rotation
520
teres major function
adduct and axternally rotate shoulder
521
teres major innervation
lower subscapular nerve
522
supraspinatus fx
0-15degrees abduction
523
where do rotator cuffs insert
supraspinatus, infraspinatus and teres minor - insert onto greater tubercle of humerus subscapularis inserts onto lesser tubercle of humerus
524
nerve supply to rotator cuffs
supraspinatus - suprascapular nerve infraspinatus - suprascapular nerve subscapularis - upper and lower subscapular nerve teres minor - axillary nerve
525
subscapularis fx
internal rotation
526
anterior forearm ALL muscles
superior: flexor carpi radialis flexor carpi ulnaris palmaris longus pronator teres intermediate: flexor digitorum superficialis deep: flexor digitorum profundus pronator quadratus flexor pollicis longus
527
superficial muscles of the anterior forearm all originate from
medial epicondyle
528
flexor carpi ulnaris
529
muscles of the anterior forearm all innervated by? expect for?
median nerve not FCU - ulnar n medial half of FDP - ulnar n deep muscles innervated by anterior interrosseous branch of median nerve
530
FCU: fx insertion
flex and adduct wrist inserts onto pisiform, HoH and base of 5th metacarpal
531
palmaris longus: fx insertion
flex wrist inserts onto flexor retinaculum
532
flexor carpi radialis: fx insertion
flex and abduct wrist inserts onto 2nd and 3rd metacarpal
533
pronator teres: originS insertion fx
head 1 - medial epicondyle head 2 - coronoid process of ulnar insert onto midshaft radius fx - pronation
534
FDS what lies between 2 heads?
ulnar artery and median nerve
535
FDS origins insertion fx
medial epicondyle and radius --> 4 tendons at wrist which attach to base of middle phalanx flex wrist, flex MCPJ and proximal IPJ
536
FDP action
flex Distal IPJ and MCPJ and wrist
537
FPL fx
flex all joints of thumb
538
FPL insertions
attach onto base of distal phalanx of thumb
539
pronator quadratus insertions
anterior ulnar to anterior radius
540
muscles in posterior forearm
superficial brachoradialis extensor carpi radialis longus extensor carpi radialis brevis extensor carpi ulnaris extensor digitorum communis extensor digit minimi aconeus deep supinator extensor pollucis longus extensor pollicis brevis abductor pollicis longus extensor indicis propius
541
superficial muscles of posterior forearm
brachoradialis extensor carpi radialis longus + brevis extensor carpi ulnaris extensor digitorum communis extensor digit minimi aconeus
542
deep muscles of posterior forearm
extensor pollicis longus extensor policis brevis abductor poliicis longus extensor indicis propius supinator
543
muscles in posterior forearm innervated by?
radial nerve
544
what is special about brachoradialis
paradoxical muscle origin and innervation suggest extensor, but is a flexor
545
brachoradialis origin, insertion, fx
lateral humerus onto distal radius flex at elbow and supination at proximal RUJ
546
extensor carpi radialis longus and brevis insertions
longus: supracondylar ridge to MC II and III brevis: lateral epicondyle to MC II and III
547
extensor carpi radialis fx
extend and abduct wrist
548
extensor digitorum communis fx insertions
main flexor of fingers lateral epicondyle --> extensor hood of each fingers
549
extensor digiti minimi insertions and fx
lateral epicondyle to extensor hood of 5th finger fx - extend all little finger joints
550
extensor carpi ulnaris fx and insertions
extend and adduct wrist lateral epicondyle to MC V
551
aconeus fx
extend and stablise elbow
552
supinator makes up what part of cubital fossa
floor
553
deep muscles of the posterior forearm are innervated by?
posterior interosseous branch of radial nerve
554
difference in fx between EPL and EPB
longus extends all thumb joints INCLUDING IPJ brevis only extends MCPJ and CMCJ
555
thenar muscles are innervated by
recurrent branch of median nerve
556
opponens policis insertions and fx
tubercle of trapezium onto lateral margin of MC I fx - medial rotation and flexion at CMCJ
557
abductor policis brevis insertions
tubercle of scaphoid and trapezium onto lateral side of proximal phalanx
558
opponens digit minimi origin
hook of hamate
559
abductor digiti minimi origin
pisiform
560
flexor digiti minimi brevis origin
hook of hamate
561
lumbricals fx
flex and MCPJ and extend at IPJ
562
palmaris brevis fx and innervation
wrinkles skin in hypothenar region and ulnar n
563
adductor policis innervation
ulnar n
564
cranial nerves carrying parasympathetic fibres
3, 7, 9, 10
565
fasciola hepatica definition
common liver fluke from parasitic infection by trematode
566
fasciola hepatica symptoms
acute - abdo pain, fever chronic - bile duct infection - jaundice
567
dx of fasciola hepatica
stool sample +/- serology
568
tx of fasciola hepatica
triclabendazole +/- ERCP
569
inflammatory breast carcinomas risk factors
pregnancy lactation
570
branchial cyst excision - nerves at risk of injury
mandibular nerve greater auricular nerve accessory nerve
571
cryptochidism causes
idiopathic patent processus vaginalis cerebral palsy wilms tumour developmental delay
572
differentials for cryptochidism
could be retractile testes could be absent testes ix - try to locate testes and move into scrotum. if it stays immediately after --> probably retractile
573
reasons to correct cryptochidism
infertility increased risk of seminoma (40x) risk of torsion cosmetic
574
cryptochidism tx
orchidopexy at 6m-18m if identified later - orchidectomy (sertoli cells already degraded)
575
episiotomy usually requires which nerve block
pudendal nerve
576
pudendal nerve innervates
anal sphincters and external urethral sphincters
577
acute inflammation general phases
1. vascular phase 2. cellular phase
578
vascular phase of inflammation
1. vasodilation of arterioles and capillaries which increases blood flow to area (calor and rubor) 2. increased vascular permeability 3. this allows protein, cells and fluids to leave the blood vessel to form exudate
579
exudate formation
made by starling forces 1. hydrostatic forces - force exerted by fluid which forces fluid out 2. oncotic pressure - force exerted by colloids to draw fluid in
580
neutrophil role in acute inflammation
1. margination 2. rolling 3. adhesion 4. emigration - into blood vessel wall
581
sign of chronic infection
granuloma formation
582
AA vs AL amyloidosis
AA secondary to chronic inflammatory conditions e.g. IBD or RhA
583
complications of renal transplantation
common - blocked catheter or hypovolaemia vascular - renal artery thrombosis SUDDEN UO CESSATION or renal artery stenosis immunological - graft rejection urological -obsturction
584
vascular cx of renal transplant
<1% typically results in graft loss usually due to technical problem sudden cessation of UO
585
salter harris types
SALTER S straight (T1) through GP A above (T2) through GP and into metaphysis L lower (T3) through GP and into epiphysis T through (T4) through GP, epiphysis and metaphysis E everything (T5) - crush T2 MOST COMMON
586
brachial plexus definition
anterior rami of c5-t1
587
brachial plexus 5 parts
roots trunks division cords branches
588
brachial plexus roots relationship to scalene muscles
pass between anterior and medial scalene muscles
589
roots to trunks brachial plexus
roots converge to form 3 trunks at base of neck: 1. superior trunk - c5+c6 2. middle trunk - c7 3. inferior trunk - c8 +t1
590
trunks to divisions brachial plexus
each trunk forms an anterior and posterior division leaves 3x anterior and 3x posterior divisions (anterior superior trunk division, posterior superior trunk division etc)
591
divisions to cords brachial plexus
3 cords named accordingly to position to axillary artery lateral cord - anterior division of superior trunk and middle trunk posterior cord - all posterior divisions (superior, middle and inferior) medial cord - anterior division of inferior trunk
592
which nerves are posterior to axillary artery
axillary nerve radial nerve
593
ulnar nerve in relation to axillary artery
medial to axillary artery
594
musculocutaneous nerve in relation to axillary artery
lateral to axillary artery
595
axillary nerve sensory branch
superior lateral cutaneous nerve
596
median nerve roots
c6-t1 (c5 in some individuals)
597
radial nerve roots
c5-t1
598
axillary nerve roots
c5,c6
599
ulnar nerve roots
c8-t1
600
musculocutaneous nerve roots
c5-c7
601
sensory branches of median nerve
palmar cutaneous branch - lateral palm sensation digital cutaneous branch - lateral 3.5 fingers
602
minor branches of brachial plexus
roots - dorsal scapular nerve, long thoracic nerve trunks - suprascapular nerve & nerve to subclavius lateral cord - lateral pectoral nerve medial cord - medial pectoral nerve posterior cord - upper and lower subscapular nerve
603
MCN anatomical course
pierces coracobrachialis passes deep to bicep passes superior to brachialis emergees lateral to biceps tendon where it gives off lateral cutaneous branch (sensation of lateral forearm)
604
radial nerve - as it passes down humerus, accompanied by which artery
brachial artery
605
how does radial nerve enter forearm
anteriorly to lateral epicondyle
606
radial nerve branches in ACF:
1. deep - motor of posterior forearm 2. superficial - sensory
607
axillary nerve passes ____ to surgical neck of humerus
medial
608
3 branches of axillary nerve
posterior terminal branch - teres minor + rear delt anterior terminal branch - supply front delt articular branch - supply GHJ
609
median nerve descends down humerus, ____ to brachial artery
laterally then crosses medially halfway down humerus
610
branches of median nerve
in forearm: 1. anterior interosseous --> deep anterior forearm muscles 2. palmar cutaneous nerve --> lateral palm sensation in carpal tunnel: 1. recurrent --> thenar 2. palmar digital nerves --> lateral lumbrical (motor) and lateral finger sensation
611
why is there preserved lateral palm sensation in carpal tunnel syndrome
palmar cutaneous nerve does not pass through carpal tunnel
612
supracondylar fractures damage which nerve
initially - anterior interosseous nerve (median) most common post-op - ulnar nerve is most common (by k-wire)
613
hand branches of ulnar nerve
deep branch - supplies hypothenar superficial branch - medial 1.5 fingers
614
ulnar nerve in relation to axillary artery and vein
ulnar nerve is medial to axillary artery ulnar nerve is lateral to axillary vein
615
ulnar nerve entering forearm
passes posterior to medial epicondyle
616
froment's sign
ulnar nerve palsy test tests adductor policis hold paper between thumb and index finger lack of thumb adduction and compensation by flexing IPJ is positive
617
froment's sign tests which muscle
adductor policis
618
hypochonium of nail
area distal to nail bed, under the free edge of nail plate
619
eponychium
stratum corneum layer at base of nail
620
germinal matrix of nail
cells that become keratinized to become nail plate
621
3 possible outcomes of peripancreatic fluid collection post-pancreatitis
1. resolution 2. pseudocyst 3. abscess
622
psuedocyst of pancreas features
high amylase in 75% most are retrogastric PRESENT >4 WEEKS AFTER ACUTE PANCREATITIS
623
tx of pseudocyst
endoscopic or surgical cystogastrostomy or aspiration
624
father can consent if....
1. married to biological mother OR 2. on birth certificate
625
renal cell carcinoma tx
t1 = partial nephrectomy t2 = radical nephrectomy no need for neoadjuvant chemo if resection is complete
626
nerve repair growth rate
1mm/day
627
lobular carcinoma in situ - distinct features
low malignancy risk can observe need MRI
628
risk factor for lobular carcinoma in situ
previous contralateral breast cancer
629
risks of aortic aneurysm over 5 years
5-5.9 cm = 25% 6-6.9 cm = 35% >7.0 cm = 75%
630
anything over ____ cm on USS for aortic aneurysm needs a CT scan
5 cm
631
CEA also high in
colitis (IBD) cirrhosis
632
osteomyelitis of spine predilects to which part of spine
cervical
633
TB of spine predilects to which part of spine
thoracic
634
carcinoid ix
24hr urine collection of 5-hydroxindoleacetic acid CT
635
carcinoid tx
if <1.2cm and limited to appendix - DISCHARGE if >2cm need isotope scan --> if mets --> right hemicolectomy octreotide often given
636
charcot foot definition
occurs in patients with peripheral neuropathy where trauma occurs to neuropathic extremities leading to bone and soft tissue/joint damage
637
what nervous system predominates post-op
sympathetic
638
body responses to surgery (4)
1. NA and A facilitated sympathetic drive resulting in bronchodilation, increased glucagon, decreased cortisol, increased HR, increased contractility 2. increased APP 3. increased nitric oxide from vessels 4. endocrine --> increased cortisol
639
tunnelled vs non-tunnelled lines
tunnelled lines have a different exit point (not same as entry point) - they are inserted under skin - have a cuff to anchor to skin - are for longer term infusions e.g. dialysis and chemotherapy examples include groshong and hickmans
640
groshong vs hickmanns
groshong has 3 way valve
641
omphacele vs gastroschisis
omphacele - abdominal contents covered in peritoneum gastroschisis - abdominal contents not covered by peritoneum
642
ligament anterior to spleen
gastrosplenic ligament (part of greater ommentum)
643
ligament posterior to spleen
leinosplenal ligament
644
indications for pre-operative enteral feeding
patients having major abdominal surgery who are: malnourised, have an unsafe swallow or inadequate oral intake but have functional GIT
645
ITU patient feeding
continuous enteral feeding 16-24 hours
646
enteral feeding options
gastric feeding unless upper GI problem - then duodenal or jejunal feeding
647
PEG can be used when after insertion
after 4 hours post-insertion
648
best sterilising method for tubercle bacili
autoclaving
649
what is autoclaving
air removed & high pressure steam used
650
pulmonary artery occlusion pressure is an indirect monitor of
left atrial pressure / filling of left side of heart
651
PAOP interpretation
normal = 8-12 low <5 = hypovolaemia low w/ pulmonary oedema <5 = ARDS high >18 overload
652
what can be damaged in anterior resection
left ureter (near upper rectum/sigmoid)
653
dorsalis pedis is a branch of
anterior tibial artery
654
what structures can be damaged in caecum operations
right ureter + gonadal arteries
655
which adenoma in colon has highest malignancy risk
villous adenoma
656
colorectal cancer follow up after resection
colonoscopy 1year post op
657
high risk features found on baseline colonsocopy - how to follow up
3 year colonoscopy
658
branches of facial nerve
when it passes through IAM - has 3 branches: 1. greater petrosal nerve 2. nerve to stapedius 3. chorda tympani then passes through SMF and has 2 branches: 1. posterior auricular 2. branch of posterior digastric belly then passes through parotid and has 5 branches: Temporal nerve Zygomatic nerve Buccal nerve Marginal Mandibular Cervical nerve
659
diagnosis of transitional cell carcinoma
CT IVU
660
most renal tumours are what colour?
yellow or brown
661
pathology - colour of TCC
pink fleshy
662
nephroblastoma tx
surgical resection combined with chemotherapy (usually vincristine, actinomycin D and doxorubicin)
663
neuroblastoma definition
nerve cell cancer
664
neuroblastoma tx
surgical resection, radiotherapy and chemotherapy
665
most common extracranial tumour of childhood
neuroblastoma
666
angiomyolipoma associated neurological condition
tuberous sclerosis
667
radial head fracture
proximal forearm tenderness pain on pronation and supination
668
An upper GI endoscopy is performed and an ulcer is seen at the greater curvature of the stomach that is actively bleeding. What vessel is most likely to be involved?
gastroepiploic artery.
669
non surgical treatment of keloid scars
triamcinolone
670
giant cell tumour of the bone (osteoclastoma) xray appearance
soap bubble appearance - multiple lytic and lucent appearances
671
bones usually affected by osteoid osteoma
femur and tibia
672
commonest benign tumour of the bone
osteoid osteoma
673
Mirel Scoring system use
stratify the risk of spontaneous fracture for bone metastasis of varying types and thus identify those that need prophylactic fixation
674
Boerhaaves syndrome definition
spontaneous rupture of the oesophagus that occurs as a result of repeated episodes of vomiting
675
where is the rupture typically located in boerhaave's syndrome
left sided and distal
676
why do you ventilate head injured patients
prevents hypercapnia prevents vasodilation, reducing blood flow to brain and therefore ICP
677
tranexemic acid MOA
prevents plasminogen to plasmin prevents clot from being broken down
678
pseudomyxoma peritonei: definition where do they arise
rare mucinous tumour most commonly arising from appendix but also bladder and ovaries
679
680
risk factors for pseudogout
hyperPTH hypothyroidism haemochromatosis
681
why is haemochromatosis a RF for pseudogout
iron causes overstimulation of osteoclasts
682
causes of hydronephrosis
UNILATERAL: PACT Pelvic-ureteric obstruction Aberrant blood vessels Calculi Tumours BILATERAL: SUPER Stenosis of urethra Urethral valve Prostatic enlargement Extensive bladder tumour Retro-peritoneal fibrosis
683
lymphatic drainage from inferior to dentate line
inguinal nodes
684
why can hypocalcaemia occur in hyperventilation
hyperventilation --> respiratory ALKALOSIS --> bound hydrogen ions dissociate from albumin leaving more albumin to bine to ionized calcium
685
prostate cancer tx
1. if old, multiple co-morbidities or low gleason score - WATCH AND WAIT 2. external beam radiotherapy - both palliative and curative therapy possible. radiation proctitis and rectal malignancy are later problems 3. radical prostatectomy - for localised disease or young patients. Erectile dysfunction common SE 4. Hormonal therapy - anti androgen or LHRH analgoues. Testosterone stimulates prostate tissue
686
A 35 year old man falls and sustains a fracture to the medial third of his clavicle. Which vessel is at greatest risk of injury?
subclavian vein
687
common organisms causing maxillary sinusitis
haemophilus influenzae strep pneumoniae
688
malignancies of the nose and paranasal sinuses
adenoid cystic carcinoma squamous cell carcinoma adenocarcinoma
689
adenocarcinoma of the paranasal sinus and nasopharynx linked to what exposure
hard wood dust
690
ameloblastomas definition
rare tumours of odontogenic epithelium they have a rim of periosteum that when palpated gives rise to crepitus
691
in normal distribution data - what percentage of values lies between: 1 SD of mean 2 SD of mean 3 SD of mean
68.27% 95.54% 99.73%
692
what stimulates prolactin release
TRH (dopamine inhibits)
693
superficial partial thickness burns characteristics:
- form vesicles and bullae - preservation of hair follicles - healing by re-epithelialisation
694
plasma typically accounts for what percentage of body weight
4-6%
695
what % of body water is intracellular
65%
696
what % of body weight is intracellular
40%
697
which dermatome requires blockade in local anaethetic open inguinal hernia repair
T12
698
Which nerve wraps around Wharton's duct (submandibular duct)
lingual nerve
699
flail chest with sats<90% mx
intubation and ventilation
700
full spine immobilisation if:
GCS<15 neck pain/tenderness paraesthesia extremities focal neurological deficit suspected c-spine injury
701
cspine injury: Xray or CT
CT if: - intubated - GCS <13 - normal Xray - any focal neurology - a CT head is being performed - Xray is abnormal
702
what 2 cranial nerves may be non-functioning in hyperacusis?
facial nerve - impaired innervation to stapedius trigeminal nerve - increased tensor tympani innervation
703
porta hepatis transmits what structures
common hepatic duct hepatic artery portal vein SNS and PSNS fibres lymphatic drainage of the liver
704
papillary thyroid spread
lymphatic
705
follicular thyroid cancer spread
haematogenous
706
berrys sign
absence of carotid pulse due to malignant thyromegaly
707
friebergs disease
anterior metatarsalgia affecting the head of the second metatarsal usually associated to pubertal growth spurt
708
use of alginate dressing
for abscess or highly exudating wounds used after incision and drainage alginate is a calcium compound acting as a haemostat
709
fissure in ano tx
stool softerners + topical diltiazem or GTN if topical fail -> botulinum toxin injection if botulinum toxin fails --> sphincterotomy
710
711
osteopetrosis definition
osteoclast function problem bones become overly dense --> brittle --> fracture
712
rectal cancer staging
MRI rectum + CT CAP
713
colon cancer staging
CT CAP
714
which menisci is usually affected in injury? and why do most sympatomatic tears need treatment?
medial menisci have no nerve or blood supply to heal poorly
715
urethral injury triad of sx
urinary retention perineal haematoma blood at the meatus
716
dieulafoy lesion
large tortuous artery most commonly in the stomach wall that erodes and bleeds
717
A 23 year old man is readmitted following a difficult appendicectomy. His wound is erythematous and, on incision, foul smelling pus is drained. Which of the organisms listed below is responsible?
bacteroides fragilis
718
septic shock precise meaning
refers to refractory systemic arterial hypotension in spite of fluid resuscitation
719
vasopressors vs ionotropes
vasopressors increase blood pressure by constricting blood vessels which increases the amount of blood that can flow to organs ionotropes increase the heart's ability to contract, which imrpoves cardiac output and help maintain BP
720
phrenic nerve - which triangle of the neck
posterior
721
Rectal cancers with threatened resection margins management
radiotherapy and chemotherapy
722
frank haematuria + high RBC?
renal cell carcinoma (not bladder) because RCC cause polycythaemia
723
angiotensinogen to angiotensin 1. which enzyme
renin
724
cerebral perfusion pressure =
mean arterial pressure - ICP
725
mean arterial pressure =
diastolic +0.33(SBP - DBP)
726
phases of wound healing
1. haemostasis 2. inflammation - neutrophils, fibroblasts and macrophages 3. regeneration - fibroblasts, endothelial cells and macrophages 4. myofibroblasts
727
tracheomalacia
collapse of airway due to cartilage degeneration (collapses in expiration) can occur after removal of very large thyroids/goitre
728
femoral nerve (L2-L4) palsy sx
weak hip flexion weak knee extension impaired quadriceps reflex sensory deficit in anteromedial aspect of the thigh
729
what muscles do femoral nerve innervate
pectineus sartorius quadriceps muscles
730
branches of the femoral nerve
medial cutaneous nerve of thigh saphenous nerve intermediate cutaneous nerve of thigh
731
which gut hormone is dependent of vagal stimuli
gastrin
732
what autosomal dominant neurological condition causes discrepancies in limb length
neurofibromatosis type 1
733
The inferior aspect of the vagina drains to which of the following lymph node groups?
superficial inguinal nodes
734
superior aspect of the vagina lymph node drainage
internal and external iliac nodes
735
which muscles attach onto greater trochanter
piriformis obturator internus gemelli obturator externus
736
anal cancer tx
chemoradiotherapy (different from rectal cancer)
737
medications causing pseudohaematuria
rifampicin phenytoin levodopa methyldopa quinine
738
DIC dx
fibrin degredation products are raised
739
DIC definition
dyregulation between coagulation and fibrinolysis - mediated by the abnormal exposure of TF in the circulation
740
Via which structure does cerebrospinal fluid enter the subarachnoid space?
Laterally: foramen of Luschka (from 4th ventricle) Medially: foramen of Magendie (from 4th ventricle)
741
stable bleeding peptic ulcer tx
adrenaline injection + endoscopic clipping/heat therapy
742
cushings triad
HYPERTENSION bradycardia respiratory depression
743
pancreatic cancer with mets tx
ERCP and stent and palliation
744
head of pancreas cancer tx
Whipple's + adjuvent chemo newer techqiues include pylorus preservation and SMA/SMV resection
745
carcinoma of pancreas body and tail
distal pancreatectomy + adjuvant chemo
746
vertebral level of left main bronchus
T6
747
inferior border of both lungs
6th rib MCL 8th rib MAL 10th rib posteriorly
748
popliteal fossa contents (medial to lateral)
popilteal artery popliteal vein tibial nerve common peroneal nerve
749
thoracic aorta rupture CXR
widened mediastinum trachea/oesophagus to right depression of left main stem bronchus widened paraspinal interfaces
750
DALM lesions tx
seen in longstanding ulcerative colitis panproctocolectomy
751
homonymous hemianopia with macula sparing lesion location
occipital cortex
752
which finger has no attachment of the palmar interosseous
middle finger
753
how do catecholamines work as ionotropes
increase cAMP levels by adenylate cyclase stimulation this increases intracellular calcium ion mobilisation and thus the force of contraction
754
adrenaline receptor preference
alpha agonist at lower doses beta agonist at higher doses
755
tranexamic acid MOA
competitively inhibits conversion of plasminogen to plasmin
756
unilateral isolated cleft lip cause
incomplete fusion of the nasolabial muscle rings
757
Contents of carotid sheath:
Common carotid artery Internal carotid artery Internal jugular vein Vagus nerve
758
post-transplant viral complications
CMV - 4weeks-6m EBV >6m (post-transplant lymphoproliferative disorder)
759
most gastric malignancies are....
adenocarcinoma
760
the tunica vaginalis is derived from -----
peritoneum
761
vein mapping investigation
venous duplex > venous doppler
762
coarctation of aorta tx
angioplasty
763
tumours of the posterior tongue metastasize to
bilateral deep cervical nodes
764
lymphatic drainage from the tip of the tongue
submental nodes
765
lymphatics from the medial mid portion of the tongue drain into
submandibular nodes? bilateral deep cervical nodes
766
lymphatics from the lateral mid portion of the tongue drain into
ipsilateral deep cervical nodes
767
rome IV criteria for IBS
recurrent abdo pain or discomfort at 3 days/ month for >3months associated with: 1. improvement with defecation 2. onset associated with a change in the frequency of stool 3. onset associated with a change in the form of the stool
768
which thyroid cancer linked to non-therapeutic irradiation
papillary thyroid
769
main pancreatic duct embryological origin
ventral outgrowth of the duodenum
770
which bacteria implicated in cholangitis infections
e.coli
771
Paneth cells - what are they and where are they located
Secretory cells that contribute to the gut micobiome Crypt of lieberkuhn
772
where do the 3 adrenal arteries arise from
superior - inferior phrenic middle - aorta lower adrenal vessels - renal vessels
773
femoral canal borders
lateral - femoral vein medial - lacunar ligament anteriorly - inguinal ligament posteriorly - pectineal ligament
774
how is tamoxifen a RF for endometrial cancer
is an ER antagonist in breast BUT agonist in endometrial tissue
775
Patients being monitored for HCC: if they have rise in AFP + USS show nodule -> diagnostic scan?
Liver MRI
776
saphena varix O/E
blue discolaration enlarge during coughing disappear on lying down
777
what nerve lies medially to lobes of thyroid and is betewen thr oesophagus and trachea
recurrent laryngeal nerve
778
phrenic nerve: does it pass anteriorly or posteriorly to the following structure: Subclavian vein Subclavian artery Lung roots
SCV - travels posterior to SCV SCA - travels anterior to SCA lung roots - travels anteriorly to lung roots
779
vagus nerve leaves cranium via
jugular foraemne
780
right vagus nerve anatomical course in the neck
passes anterior to the subclavian artery
781
left vagus nerve anatomical course in the neck
passes between the left common carotid and left subclavian artery
782
hyperplasia vs hypertrophy
hyperplasia - increase in number of cells hypertrophy - increase in size of cells
783
what happens when catheter enters prostatic urethra
resistance decreases (as it is much wider)
784
arterial supply of prostate
inferior vesical artery (branch of internal iliac)
785
prostate lymph drainage
internal iliac
786
prostate innervation
inferior hypogastric plexus
787
where do most prostate cancers occur in prostate
peripheral zones
788
what causes high amylase
acute pancreatitis acute cholecystitis DKA mesenteric infarct
789
what hormones are decreased in stress response
insulin testosterone oestrogen thyroxine
790
hormonal affects on pancreatic secretions
SECRETIN - causes secretion of water and electrolytes CCK - causes enzyme secretion Somatostatin - decreases volume of secretion
791
loop diuretic MOA
inhibit Na/K/Cl transporter in ascending limb of Henle reduces absorption of NaCl
792
Thiazide site of action
distal tubule
793
if colonoscopy is indicated but cannot be tolerated - which scan is next
CT colonography
794
stridor after thyroid surgery management
re-open neck wound by removal of skin clips ON THE WARD
795
drugs that can cause parotid enlargement
high oestrogen dose contraceptives thiouracil isoprenaline
796
permanent sutures
polypropylene polyester
797
when should clopidegrel be stopped before surgery
5-7d before reduces ADP induced platelet aggregation for 120hours after final dose
798
heterotropia
tissue found in abnormal location that is present from birth e.g. Meckels (gastric mucosa)
799
most common extra-colonic lesion in FAP?
duodenal polyps
800
external jugular vein relation to sternocleidomastoid
lateral / superficial
801
right recurrent laryngeal nerve anatomical course
branches off right vagus nerve more proximal than T4 it arches posteriorly around the subclavian artery
802
lady having splenectomy for ITP - when to give platelet transfusion?
AFTER ligation of the splenic artery before surgery - platelets would be sequestered by spleen
803
differences in procedure of splenectomy in emergency vs elective
most elective are laparoscopic
804
cx of splenectomy
haemorrhage pancreatic fistula thrombocytosis encapsulated bacteria infection
805
CKK effects on rate of gastric emptying
reduce rate
806
factors increasing gastric acid production
vagal nerve stimulation gastrin release histamine release
807
factors decreasing gastric acid production
somatostatin CKK secretin
808
dercums disease
multiple lipomas + generalized obesity
809
statistical power definition
probability of a test that it will reject the null hypothesis when it is false (thereby avoiding type 2 error)
810
normal statistical power desired
0.8
811
type 1 error
a test rejects a TRUE null hypothesis (false positive). it equates to the significance of a test
812
type 2 error
a test fails to reject a false null hypothesis related to statistical power
813
components needed for power calculations
size of effect significance level sample size desired power
814
where do vertebral arteries unite to form basilar artery
base of the pons
815
branches of the vertebral arteries
PICA anterior spinal artery posterior spinal artery
816
basilar artery branches
pontine arterie AICA superior cerebellar artery posterior cerebral artery
817
what passes posterior to the medial malleolus
tibialis posterior tendon flexor hallucis longus tendon flexor digitorum longus tendon tibial nerve posterior tibial artery
818
locations of accessory spleens (8)
tail of pancreas splenic vessels gastrosplenic ligament splenrenal ligament walls of the stomach and intestines greater omentum mesentery gonads
819
adrenal masses of what size need to be removed
>4cm
820
most significant event to contribute to wound healing immediately following injury
platelet degranulation
821
fistula in ano cell type
squamous
822
respiratory centres
1. medulla respiratory centre 2. apneustic centre 3. pneumotaxic centre
823
apneustic vs pneumotaxic centre
pneumotaxic centre in upper pons apneustic centre in lower pons pneumotaxic centre overrides apneustic cntre and can inhibit inspiration
824
where are respiratory chemoreceptors
central - medulla peripheral - carotid and arch of aorta
825
central chemoreceptors in medulla respond to
H+ in brain interstital fluid
826
obstructing renal cancer stoma
loop colostomy - to defuntion distal segment of colon
827
loop ileostomy indications
defunction distal bowel in low anterior resection
828
spongy urethra and glans penis lymphatic drainage
deep inguinal nodes
829
additional antibiotics to consider for MRSA (in addition to glycopeptide)
rifampicin macrolides tetracyclines
830
bone mets that are hypervascular primary source?
renal cancer
831
prilocaine antidote
methylene blue reverts ferric type to ferrous type Hb
832
scrotal sensation
ilioinguinal nerve - anterior pudendal - posterior skin
833
SOMATOSTATIN FUNCTIONS
1. inhibit GH 2. delays gastric emptying 3. reduces gastric acid production 4. reduces pancreatic exocrine secretions
834
suspicious melanoma lesions should undergo which ix
excision biopsy
835
long head of biceps femoris innervation
tibial division of sciatic nerve
836
short head of biceps femoris innervation
common peroneal nerve
837
hydrocele tx
children - transinguinal ligation of the patent processus vaginalis adults - Lords of Jabouley procedure
838
lord vs jabouley procedure of hydrocele
Lord - plication of sac Jabouley - sac drained, everted and sutured behind testes Jabouley for larger hydrocele; lower risk of recurrence but higher risk of haematoma
839
comedo vs cribiform DCIS
comedo - microcalficications cribiform - multifocal
840
hyoid vertebral level
C3
841
notch of the thyroid cartilage vertebral level
c4
842
cricoid cartilage vertebral level
c6
843
what landmarks are at C6
junction of larynx with trachea junction of pharynx with oesophagus inferior thyroid artery enters thyroid middle cervical ganglion level
844
open fractures >6 hours ago mx
amputation
845
hartmans procedure risk of wound infection
35%
846
preparation for endoscopy
colonoscopy = oral purgatives day before sigmoidoscopy = eneme 30 mins before OGD = NBM for 6 hours
847
where does apneuorsis end
below arcuate line
848
high output fistula management
octreotide - limit pancreatic secretions nutritional complications nutritional support is common - TPN
849
perianal fistulae secondary to Chrons mx
seton
850
nephroblastoma vs neuroblastoma
nephroblastoma are non-calcified neuroblastoma are usually calcified
851
drug causing goitre
lithium
852
when do callus become visible on radiographs after fracture
3 weeks
853
which cell type relies on Cori cycle alone for energy needs
erythrocytes - lack mitochondria
854
parenteral nutrition - what needs to be monitored
zinc folate b12 copper iron ferritin magnesium vitamin d bone density
855
intra-op arterial bleeding mx
ligation
856
proximal humerus fractures mx
impacted fractures - collar and cuff for 3 weeks displaced - ORIF
857
drugs reducing renin secretion
beta blockers NSAIDs
858
which scaphoid fractures need surgery
1. displaced 2. all proximal pole fractures
859
splenic vein thrombosis: dx cx tx
dx - CT angio cx - varices tx - splenectomy
860
During an Ivor Lewis Oesophagectomy for carcinoma of the lower third of the oesophagus which structure is divided to allow mobilisation of the oesophagus?
azygous vein
861
gritti stokes amputation
remove part of femur. connect remaining femur to patella
862
skew flaps benefits
less bulky easier to attach prosthesis to
863
late sign of compartment
lossof pulses
864
pelvic fracture and lwoer abdominal peritonism ....?
bladder rupture
865
large bowel obstruction with visible fluid level cause
sigmoid volvulus
866
what aspect of RAAS causes vasoconstriction
angiotensin II
867
burns + bad ventilation in patient who already intubated
escharotomy
868
colonic pseudoobstruction mx
supportive - electrolyte replacement sometimes neostigmine required to stimulate peristalsis
869
suture for securing drains
2/0 silk
870
what type of smooth muscle propels food through the oesophagus
longitudinal smooth muscle
871
how long does it take food to get from oesophagus into the stomach
9 seconds (primary peristalsis)
872
three main types of peristaltic activity in the colon
1. segmentation contractions - localised contractions in which the bolus is subjected to local forces to maximise mucosal absorption 2. anti-peristaltic contractions - reverse peristaltic waves to slow entry into colon and maximise absorption 3. mass movements
873
discitis organisms in children
0-6m = staph aureus 6m-4y = kingella kingae
874
cluster RCT vs normal RCTs
randomize GROUPS vs individuals more prone to error they require increased recruitment to achieve the same level of statistical power
875
what ligament seperates vertebral column vs spinal cord
posterior longitudinal ligament
876
what blood vessel is divided in lateral approach for hip arthroplasty
transverse branch of the lateral circumflex artery
877
brisk haematuria in pregnancy
placenta PERCRETA - invades mymometrium and can extend into bladder
878
hashimoto's can lead to which cancer
thyroid lymphoma (MALT)
879
most posterior structure at the hilum of the kidney
ureter
880
body of uterus drains into which lymph node
iliac lymph nodes
881
ovaries drain into which lymph node
para-aortic lymph nodes
882
MEN IIB
medullary thyroid phaeochromocytoma mucosal neruroma marfanoid features
883
MEN I
pancreatic/ZES parathyroid pituitary
884
MEN IIA
Phaeochromocytoma Medullary thyroid HyperPTH
885
difficult viewing during cholecystectomy - how to manage
cholecystostomy - drainage of gall bladder
886
sarcomas spread how? and where commonly
haematogenous lung common site
887
parotid gland secretions account for what percentage of secretions to saliva
25%
888
PTH half life
10 mins
889
which parasitic infection affects gut and lungs
ascariasis
890
duct ectasia tx
multiple ducts = hadfields procedure single duct = microdochectomy
891
stroke volume range
55-100ml
892
coronary arteries have which adrenergic receptors
Beta2
893
most common cause of bacterial infective diarrhoea
campylobacter jej
894
causes of hyperuricaemia
severe psoriasis lesch-nyhan syndrome DKA alcohol
895
which 2 arteries run near SFJ
deep external pudendal artery superficial external pudendal artery
896
contents of greater sciatic foramen
sciatic nerve pudendal nerve superior and inferior gluteal nerves nerve to quadratus femoris nerve to obturator internus superior gluteal artery and vein inferior gluteal artery and vein internal pudendal artery and vein
897
hypokalaemia is associated to which pH imbalance
alkalosis
898
posterior urethral valve tx
endoscopic valvotomy
899
Which substance is released from the sympathetic nervous system to stimulate the adrenal medulla?
acetyl choline
900
worm infection of anus most common
enterobius vermicularis
901
5 FU MOA
antimetabolite
902
doxorubicin MOA
Anthracycline - inhibit DNA and RNA synthesis by intercalating base pairs
903
cisplatin MOA
crosslinks DNA to induce apoptosis
904
cyclophosphomide MOA
alkylating agent
905
actinomycosis
chornic progressive granulomatosis disease caused by filamentous gram positive anaerobic bacteria
906
proximal SCC oesophageal cancer tx
chemoradiotherapy
907
lateral medullary syndrome sx
ipsilateral ataxia ipsilateral nystagmus ipsilateral facial nerve dysphagia contralateral hemisensory loss
908
saphenous nerve is related to which vein
long saphenous vein below the knee
909
long saphenous vein course
travels anterior to medial malleolus at the knee runs over the posterior border of the medial epicondyle of the femur bone
910
short saphenous vein course
posterior to the lateral malleolus passes between the heads of the gastrocnemius muscle
911
CNS tumour with sigificant necrosis
glioblastomas
912
most common paediatric CNS tumours
astrocytomas
913
cranial venous sinuses eventually drain into...
internal jugular vein
914
what is the single most important prognostic factor in breast cancer
nodal disease
915
Kocher criteria
WIFE WCC >12 Inability to weight bear Fever ESR . 40
916
lacunar infarct presentation
isolated hemiparesis isolated hemisensory or hemiparesis with limb ataxia
917
lesion affecting lobule in ear - drain into...
superficial cervical LNs
918
sartorius nerve supply
femoral nerve
919
the foramen marking the termination of the adductor canal is located in ...?
adductor magnus
920
papillary thyroid cancer tx
total thyroidectomy and central compartment nodal dissection
921
GIT surgery - what surgeries have lower rates of anastomotic leak
small intestine oesophageal and rectal have highest
922
follicular thyroid cancer tx
total thyroidectomy
923
anaplastic thyroid cancer tx
palliative radiotherapy
924
medullary thyroid cancer tx
total thyroidectomy
925
Which of the following nerves is responsible for the cremasteric reflex?
genitofemoral nerve
926
dupuytrens contracture tx
fasiectomy
927
what is the pathological size of the caecum
9+cm
928
drugs inhibiting secretion of insulin
alpha adrenergic drugs beta blockers sympathetic nerves
929
930
where are oxyphil cells found
parathyroid glands and follicular thyroid
931
GIST derived from
cells of Cajal
932
what nerve innervates perineum
pudendal n
933
CSF: lateral ventricles to 3rd ventricle foramen
foramen of Munro
934
CSF: 3rd to 4th ventricle foramen
aqueduct of sylvius
935
neurological signs + acute abdo =
acute intermittent porphyria or lead posioning
936
the activation of which clotting factor is when both intrinsic and extrinsic factors meet
factor 10
937
heparin inhibits which clotting factors
2,9,10,11
938
which is the main pathway of coagulation
extrinsinc
939
what starts extrinsic pathway
tissue factor
940
which structure is at risk of injury following a fracture dislocation of femoral epicondyles
popliteal artery
941
symptom difference between maxillary and ethmoidal sinusitis
altered sense of smell a feature of maxillary sinusitis
942
what causes a risk in TLCO
asthma haemorrhage LtoR shunts polycythaemia
943
parotid gland PSNS fibres originate from
Otic ganglion
944
saliva secretion by parotid gland nerve involvement
PREGANGLIONIC: tympanic nerve (branch of CN IX) to lessor petrosal nerve to OTIC GANGLION POSTGANGLIONIC fibres travel as part of auriculotemporal nerve (branch ofV3)
945
The parasympathetic fibres to the lacrimal apparatus transit via which ganglion
pterygopalatine
946
which ligament keeps radial head connected to radial notch of ulnar
annular ligament
947
Which of the following nerves is most often permanently damaged during a superficial parotidectomy
GREATER AURICULAR
948
Which structures pass through both greater and lesser sciatic foramina
pudendal nerve internal pudendal artery nerve to obturator internus
949
cholangitis tx
ERCP and stent
950
where is most iron absorbed?
duodenum
951
ileitis common organism
yersinia enterocolitica
952
external urethral sphincter nerve roots
s2-s4 (pudendal)
953
COCP linked to what liver disease
liver cell adenoma
954
which of the following would still be digested normally in a patient with pancreatic insufficiency? 1. Fat 2. Protein 3. Folic Acid 4. Vitamin B12
3. Folic Acid 4. Vitamin B12
955
during a splenectomy - what needs to be divided
short gastric vessels within the gastrosplenic ligament
956
WARTHIN TUMOUR CHARACTERISTICS
male elderly smokers bilateral in 10%
957
younger patient with PROXIMAL lymphoedema management ?
1. lymphovenous anastomosis
958
clinical differences between FAP and Lynch
FAP - usually 100s of polyps Lynch associated with more RHS cancers
959
axillary artery branches
FIRST SEGMENT of the axillary artery: 1. superior thoracic artery SECOND SEGMENT of the axillary artery: 1. thoracoacromial 2. lateral thoracic artery THIRD SEGMENT of the axillary artery: 1. subscapular artery 2. anterior circumflex humeral artery 3. posterior circumflex humeral artery
960
Which of the following laboratory tests would most accurately identify whether CSF is present or not?
beta-2 transferrin assay
961
Which structures are linked by the ductus arteriosus?
PA and (descending) aorta
962
persistent PDA tx
NSAIDs
963
ductus venosus connects what 2 structures
umbilical vein to IVC (to bypass the liver)
964
burns affect on potassium levels
HYPERKALAEMIA
965
JVP waveform detailing
A wave - right atria contracts X descent - RELAXATION of the right atrium causing drop in pressure C wave - tricuspid wave closes and right ventricle contract causing bulging of TV which transiently increases pressure in RA therefore JVP X descent - complete RV contraction allowing atria to expand - pressure drops V wave - atrial filling with bloods (against a closed tricuspid valve) Y wave - tricuspid valve opens again (JVP pressure drops)
966
tricuspid regurgitation affevct on JVP
large V waves
967
first radiological change in Perthes disease
stage II Caterall disease: Sclerosis of femoral head
968
secondary haemorrhage after tonsillectomy usual time frame
5-10 days (anything over 24hours is technically secondary haemorrhage however)
969
autonomic vs voluntary control of bladder function
autonomic - hypogastric plexuses voluntary control of urethral sphincter - pudendal nerve
970
desmoid tumours: what are they? and where do they tend to arise?
fibrous neoplasms usually arise from musculoaponeurotic structures
971
INDUCTION AGENT (SEDATIVE) BEFORE PARALYTIC AGENTS (RELAXANTS)
.
972
GOODSALLS rule
anterior fistula - tract straight posterior fistula - curvature traction only applies to fistulae within 3cm radius of anus
973
what skin rash is associated to necrolytic migratory erythema
glucagonoma
974
What type of epithelium is present on the external aspect of the tympanic membrane?
stratified squamous
975
adductor longus innervation
anterior division of obturator nerve (L2-L4
976
Which substance is commonly used to sterilize endoscopic and laparoscopic equipment?
glutaraldehyde
977
abdo + neurological symptoms niche cosiderations
think acute intermittent porphyrias think lead posioning
978
most radioopaque kidney stone
calcium phosphate
979
sensory innervation of axilla
intercostobrachial plexus
980
laboratory features of dehydration
rising haemotocrit hypernatraemia metabolic acidosis rising lactate urinary sodium<20
981
posteriorn digastric innervation
facial nerve
982
posterior approach hip replacement - which artery is at risk
inferior gluteal artery
983
popcorn cells seen in ...
nodular lymphocyte predominant HL
984
beta-napthalamine is associated with which cancer
bladder cancer
985
important structures posterior to right colon
gonadal vessels right ureter
986
distal third clavicle fracture - which artery at risk of injury
thoracoacromial artery
987
squamous cell carcinoma of skin excision margins
lesions <20mm need 4mm margin excision lesions >20mm need 6mm margin excisions
988
metastatic bone fractures - which cancers are more likely to have bone mets that fracture
breast cancer bone mets are usually lytic (prostate cancers are sclerotic)
989
990
which bone mets site is at greatest risk of fracture
peritrochanteric fracture
991
typical GFR
125ml
992
left sided SVC congenital abnormality - how does blood enter right atrium
enlarged coronary sinus
993
somatostatin effects
decrease acid and pepsin secretion decrease gastrin secretion decreases pancreatic enzyme secretion decreases insulin and glucagon secretion
994
waldeyer's fascia
posterior ano-rectum
995
sibsons fascia
apex of lung
996
bucks fascia
base of penis
997
gerotas fascia
surrounding kidney
998
denonvilliers fascia
between rectum and prostate
999
discitis in children organisms
<6m = staph aureus 6m-4y = kigella kingae
1000
which enzyme deficiency causes steatorrhoea
lipase
1001
why is tranfusion with platelets most likely to cause gram +ve infection out of all transfusion types
platelets stored at room temperature
1002
hypovolaemic shock features
decreased CO decreased BO increased HR increased SVR
1003
parathyroid embryological origin
superior parathyroids - fourth pharyngeal pouch inferior parathyroids - inferior pharyngeal pouch
1004
parathyroid relation to thyroid
parathyroid is POSTERIOR
1005
epiploic foramen contents
portal vein hepatic artery common bile duct
1006
how is the pituitary gland attached to the hypothalamus
by the infundibulum
1007
what can cause high 5-HIAA
drugs: naproxen and MAOi food: spinach, cheese, wine, caffeine, tomatoes
1008
hassall's corpuscles found in ...
medulla of the thyroid
1009
middle ear innervated by ....
glossopharyngeal nerve
1010
aptt is a measure of
intrinsic pathway
1011
instrinsic patheay of coagulation
F12> F11>F9>F10
1012
PT measure of
extrinsic pathway (TF+F7)
1013
tip of tongue lymphatic drainage
submental nodes (then to deep cervical nodes)
1014
mid portion of tongue lymphatic drainage
submandibular drainage or if lateral then ipsilateral deep cervical nodes
1015
what muscles do ansa cervicalis innervate
sternohyoid sternothyroid omohyoid
1016
From which embryological structure is the ureter derived?
mesonephric duct
1017
metallic heart valve patient needs operation - when to stop heparin
6 hours pre-op
1018
mid inguinal point
midway between the ASIS and the pubic symphysis
1019
stoma earliest complication vs most common
earliest = necrosis most common = dermatitis
1020
electrical burns fluid resus
4ml hartmanns x kg x %TBSA
1021
flame burns fluid resus
2ml hartmanns x kg x %TBSA
1022
scrotal layers
1. skin 2. dartos fascia and muscle 3. external spermatic fascia 4. cremasteric muscle and fascia 5. internal speramtic fasscia 6. parietal layer of the tunica vaginalis
1023
physiologyical insulin after surgery
reduced (so is testosterone and oestrogen)
1024
nerve most closely related to bladder
obturator bladder
1025
hormones increased after surgery
GH cortisol renin ACTH aldosterone prolactin ADH glucagon
1026
where does neonate spinal cord end
L3
1027
What increases physiological dead space
PE COPD hypotension
1028
ileo-ileal intususcception mx
rarer subtype requires laparotomy
1029
DMSA vs MAG 3 uses
DMSA best for scarring (not necessary if CT-proven) MAG-3 best for assessment of renal function in damaged kidneys
1030
renal vein in relation to renal hilum
vein is anterior
1031
ureter in relation to renal hilum
posterior to hilum
1032
transported kidney anastomised to which blood supply
external iliac artery
1033
haemangioma on ultrasound
hyperechoic
1034
pancreatic secretions volume a day
1L-1.5L
1035
What is the lymphatic drainage of the female urethra?
internal iliac nodes
1036
what type of suture is prolene
permanent monofilament
1037
vicryl type of suture
braided absorbable
1038
what type of suture is polyester
braided permanent
1039
PDS type of suture
monofilament
1040
high output stoma causes acidosis or alkalosis
acidosis
1041
superior adrenal artery is a branch of
inferior phrenic artery
1042
suxamethonium can lead to which electrolyte imbalance
hyperkalaemia
1043
structures passing through the parotid gland
facial nerve and branches external carotid artery retromanidbular vein auriculotemporal nerve
1044
which artery runs under the long saphenous vein
deep external pudendal artery
1045
what does inferior mesenteric vein drain into
splenic vein
1046
which steroid doesnt affect cortisol levels
dexamethasone
1047
incision for malrotation
transvere supra umbilical abdominal incision
1048
rectal prolapse surgery types
perineal 1. Delormes 2. Altmeirs - more effective but carries higher risk of anastomotic leak abdominal 1. rectopexy - low recurrrence rates
1049
atracurium produces what on hydrolysis
histamine
1050
What is the most important urinary acid base buffer?
phosphate
1051
toxic megacolon mx
sub total colectomy and end ileostomy
1052
brocas area is supplied. by
middle cerebral artery
1053
posterior belly of diagastric muscle supplied by
facial nerve
1054
which vessels most likely to bleed in tonsils removal
external palatine vein
1055
asteroid bodies found in which condition
sarcoidosis
1056
Administration of which of the following may facilitate the identification of parathyroid glands intra operatively?
methylene blue
1057
1058
median nerve course relative to the brachial artery
lateral>anterior>medial
1059
adductor longus innervation
obturator nerve
1060
1060
which thyroid cancer spreads haematogenously and commonly mets to bones
follicular
1061
incision for whipples procedure
rooftopv
1062
lateral to medial: foramina of skull
spinosum > ovale > rotundum SOR
1063
hydrocele mx
children - ligation of patent processus vaginalis via inguinal approach adult - jabuloay or lords via scrotal approach
1064
exposure of which fascia exposes the ansa cervicales
pretracheal fascia
1065
ansa cervicales lies _____ to carotid sheath
anterior
1066
obstructing splenic flexure cancer tx
EXTENDED RIGHT HEMICOLECTOMY IF NOT OBSTRUCTING THEN LEFT HEMICOLECTOMY
1067
MIDDLE MENINGEAL ARTERY IS A BRANCH OF....
maxillary artery
1068
What is the most important structure involved in supporting the uterus?
central perineal tendon
1069
which coagulation factor likely to be normal in liver failure
factor 8
1070
What is the level of the hyoid bone?
c3
1071
What is the commonest type of fistula in ano?
intersphincteric
1072
parasympathetic nerve supply to bladder does what
contraction of detrusor muscles
1073
What is the main component of colloid in the thyroid gland?
thyroglobulin
1074
anterior vs posterior duodenal ulcers
anterior - more likely to perforate causing peritonitis posterior - more likely to bleed
1075
Sudden onset of abdominal pain followed by forceful evacuation of bowels - think of...
acute mesenteric infarction
1076
1077
which breast cancer patients need post-op chemo
patients with grade 3 lesions or axillary node disease
1078
tenia coli converge where?
base of appendix
1079
diaphragm disease: 1. what is it 2. what causes it
rare condition that causes multiple strictures in the small bowel caused by NSAID overuse
1080
Infection with which of the following micro-organisms may result in a clinical picture resembling achalasia of the oesphagus?
TRYPANOSOMA CRUZI (Chagas)
1081
upper pole of kidney corresponds with which rib
11th
1082
colonic villous adenomas can cause which electrolyte disturbance
hypokalaemia
1083
what blood product most cocmmonly causes urticaria
FFP
1084
how can you confirm enterocutaneous fistula as appose to wound infection?
methylene blue found in the drain = fistula
1085
DIC consumes which clotting factors first
5&8 then platelets
1086
what cell type responsible for contractile nature of scar
myofibroblasts
1087
which hormone will secreted in decreased quantities after distal gastrectomy
gastrin - released from gastric antrum
1088
structures that pass posterior to lateral malleolus
peroneus brevis tendon peroneus longus tendon short saphenous vein sural nerve
1089
1089
What is the half life of insulin in the circulation of a normal healthy adult?
less than 30 mins
1090
parasympathetic affect on HR
tachycardia atropine (antiPSNS causes brady)
1091
What is the anatomical level of the transpyloric plane?
L1
1092
A 34 year old lady is due to undergo a laparoscopic cholecystectomy. Which of the following intrabdominal pressures should typically be set on the gas insufflation system?
10mmhg
1092
what proportion of fissures are anterior
10%
1093
Into which of these veins does the middle thyroid vein drain?
internal jugular vein
1094
thyroid arterial supply
superior thyroid - ECA inferior thyroid - branch of thyrocervical - branch of subclavian thyroidea ima
1095
thyroid venous drainage
superior and middle thyroid veins - drain into IJV inferior thyroid vein - into brachiocephalic
1096
sigmoid sinus drains into...
internal jugular vein
1097
radial nerve position to humerus at distal third
anterolateral
1098
one RCT is which level of evidence
II
1099
dura terminates at which spinal level
S2
1100
JUGULAR FORAEMEN PART OF WHICH BONE
temporal
1101
foramen magnum part of which bone
occipital bone
1102
suspected breast implant complication - which imaging
MRI