NIS Management Flashcards

(42 cards)

1
Q

Potential outcomes of anorexia and early satiety

A

Inadequate energy intake, unintentional weight loss, sarcopenia, nutrient insufficiency and deficiency, dehydration, and malnutrition

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2
Q

Anorexia Grade 1

A

Loss of appetite without alteration in eating habits

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3
Q

Anorexia Grade 2

A

Oral intake altered without significant wight loss or malnutrition; oral nutritional supplements indicated

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4
Q

Anorexia Grade 3

A

Associated with significant weight loss or malnutrition; tube feeding or PN indicated

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5
Q

Anorexia Grade 4

A

Life-threatening consequences; urgent intervention indicated

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6
Q

Grade 5

A

Death

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7
Q

MNT for anorexia

A

Small, frequent meals (6-8); eat by the clock; maximize intake when appetite is best; use ONS; consume liquids between meals; enhance nutrient density, if tolerated; use easily prepared foods; keep convenience foods on hand; engage in light physical activity

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8
Q

Pharmacotherapy for anorexia

A
Antihistamines (Periactin) in children
Corticosteroids (Dexamethasone)
Progestational agents (Provera, Megace)
Prokinetic agents (Reglan)
Cannabinoids (Marinol, Syndros, Casamet)
Antidepressants (Remeron)
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9
Q

Potential outcomes of dysgeusia

A

Decreased intake
Nutrient insufficiency and deficiency
Unintentional weight loss

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10
Q

Dysgeusia Grade 1

A

Altered taste, no change in diet

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11
Q

Dysgeusia Grade 2

A

Altered taste with change in diet; noxious or unpleasant taste; loss of taste

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12
Q

Constipation pharmacotherapy

A
Insoluble food fiber
Medicinal fibers
Stool softener
Lubricants
Osmotic laxatives
Stimulant laxative agents
Opioid antagonist
Herbals
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13
Q

Insoluble food fiber

A

Bran, flaxseed, wheat germ, inulin

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14
Q

Medicinal fibers

A
Psyllium (Metamucil)
Wheat dextrin (Benefiber)
Carboxymethylcellulose (Trulance)
Methylcellulose (Citrucel)
Polycarbophil (FiberCon)
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15
Q

Stool softener

A

Ducosate (Colace, Surfak)

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16
Q

Lubricants

A

Mineral oil

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17
Q

Osmotic Laxatives

A

MiraLAX (polyethylene glycol)
Lactulose (Duphalac, Cadilose)
Magnesium hydroxide (Milk of Magnesia)
Magnesium citrate

18
Q

Stimulant Laxative Agents

A

Bisacodyl (Dulcolax, Correctol, Carter’s pills)

Sennosides (Senokot, Ex-lax)

19
Q

Opioid Antagonist

A

Relistor
Amitiza
Morantik
Symproic

20
Q

Herbals

A

Probiotics, slippery elm, aloe juice, cascara sagrada

Caution: Bacteremia is possible in immunocompromised patients. Avoid opening capsules of probiotics is port is present

21
Q

Fluid needs for constipation

A

64-80 oz daily (8-10c)

Additional 32 oz if using medicinal fibers

22
Q

Fiber needs for constipation

A

Women: 25 g/d
Men: 38 g/d

Increase slowly as tolerated

23
Q

Medications that may slow gastric emptying

A
Vinca alkaloids
opioids 
aluminum hydroxide antacids
histamine H2-recepter antagonists
PPI
sucralfate
interferon
levodopa
sedatives
antiemetics
24
Q

Potential outcomes of diarrhea

A

Frequent stools, dehydration, electrolyte imbalances, unintentional weight loss, fatigue, nutrient insufficiency and deficiency, malnutrition, skin irritation

25
Treatments or medications that cause diarrhea
``` Chemo: Irinotecan, VP-16 (etoposide) RT to pelvis Antibiotics Prokinetic agents Stool softeners, laxatives Dietary causes (EtOH, caffeine, sugar alcohols, lactose, high insoluble fiber intake) ```
26
Fluid needs for diarrhea
64-80 oz (8-10c) daily | Additional 1c for each loose BM
27
Pharmacotherapy for diarrhea
Opioid receptor antagonists: Imodium AD (Loperamide), Lomotil Hormonal: Sandostatin (ocreotide) Opioids: Paregoric, camphorated tincture of opium Anti-inflammatory, anti-diarrheal: Pepto-Bismol, Kaopectate Bile acid sequestrant: Cholestyramine (Questran) Anticholinergics: diphenhydramine (Benadryl) Medicinal Fibers: psyllium (Metamucil), psyllium or calcium polycarbophil caplets (Konsyl); methylcellulose (Citracel) Preventative for gut radiotherapy: amifostine (Ethyol) Amino acids: L-glutamine (reduces duration, not severity); Enterade (blend of AA) Probiotics: saccharomyces boulardii, Lactobacillus rhamnosus GG
28
Potential outcomes for dysphagia
Coughing, choking, feeling of "food getting stuck", odynophagia, aspiration, pneumonia, weight loss, nutrient insufficiencies and deficiencies, dehydration, malnutrition
29
Thickeners
Simply Thick gel, Thicken Right, Thicken up; Thick & Easy, Thick It
30
Topical anesthetics for dysphagia
Lidocaine spray (Xylocaine)
31
Fatigue pharmacotherapy
Blood transfusions | Erythropoietin given as epoetin alfa
32
Potential outcomes for malabsorption
Abnormal digestive enzyme studies, steatorrhea, unintentional weight loss, dehydration, nutrient insufficiency and deficiency, malnutrition, fatigue
33
PERT dosing per g fat
500-1000 U lipase /g fat | Do not exceed 4000 u lipase/g fat
34
PERT dosing per kg
Do not exceed 2500 u lipase/kg/meal or 10,000 u lipase /kg /day start 500 u lipase /kg /meal, increase as tolerated 250 u lipase/kg/snack
35
PER dosing per meal
20,000-75,000 lipase/meal and 5,000-50,000 u lipase/snack
36
PERT Considerations
Some PERT require concurrent PPI to maintain effectiveness. Do not sprinkle or mix contents of capsules on diary products or consume foods with a pH >4. Sprinkle on applesauce immediately before eating a meal, if needed.
37
Potential outcomes for N/V
Dehydration, electrolyte and acid-base imbalance, nutrient insufficiency and deficiency, unintentional weight loss, aspiration, esophagitis, Mallory-Weiss syndrome, fractures, wound dehiscence, and potential withdrawal from antineoplastic treatment
38
Pharmacotherapy for acute N/V
``` Serotonin antagonists (5-HT3 receptor antagonists: Ondansetron (Zofran) Dolasetron (Anzemet) Granisetron (Kytril) Palonosetron (Aloxi) Tropisetron (Navoban) ```
39
Pharmacotherapy for Delayed N/V
``` Dopamine antagonists (Phenothiazines): prochlorperazine (Compazine), promethazine (Phenergan) ``` Nerokinin-1 (NK-1) receptor antagonists: aprepitant or fosaprepitant (Emend) netupitant / palonsetron (Akynzeo) Rolapitant (Varubi)
40
Etiology of N/V
``` Anticipatory (prior to chemo) Acute (24 hours after chemo) Delayed (1-7 days after chemo) Breakthrough (occurs despite prophylactic medications, requiring "rescue" medications) Refractory (all medications failed) ```
41
Pharmacotherapy for N/V
Benzamides: Reglan Cannabinoids: Marinol, Syndros, Cesamet Benzodiazapines: Ativan Valium Corticosteroids: Dexamethasone, prednisone
42
Complementary therapies for N/V
Ginger tea, ginger ale, 0.5-1.0 g ginger extract, acupressure bracelets, acupuncture, massage, transcutaneous electrical nerve stimulation, relaxation techniques, self-hypnosis