NM 621 exam 1 : SAB & preeclampsia Flashcards

(53 cards)

1
Q

chronic hypertension

A

BP >140/90
Before 20 weeks of gestation
No proteinuria or stable proteinuria

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2
Q

superimposed preeclampsia

A

BP>140/90
new or increase proteinuria
development of increase BPs or HELLP syndrome

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3
Q

preeclampsia

A

BP>140/90
after 20 weeks gestation
proteinuria (+1 dipstick or >3–mg) or absence of proteinuria + thrombocytopenia, renal insufficiency, impaired liver functions, pulmonary edema, or cerebral or visual symptoms

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4
Q

gestational hypertension

A

BP>140/90

no proteinuria and not symptomatic

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5
Q

management for GHTN or preeclampsia w/o severe features

A
close monitoring
serial assessment of maternal symptoms
DAILY fetal kick counts
BP 2x per week 
WEEKLY Lab : CBC & liver enzymes
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6
Q

when to referral preeclampsia

A

when symptomatic

prophylactic mag sulfate when hospitalized with symptomatic preeclampsia.

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7
Q

HELLP

A

hemolysis
Elevated liver enzymes
low platelets

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8
Q

complaints of HELLP

A

90%–> malaise fatigue and nonspecific complaints
prevalence–> N/V headache and/or abdominal pain
66% –> elevated BP

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9
Q

Gestational Hypertension

A

BP>140/90 for the 1st time during MID-pregnancy
no proteinuria
B/P returns to normal w/in 12 weeks postpartum
final dx made postpartum
50% of women dx with GHTN between 24-35weeks develop preeclampsia

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10
Q

mild Preeclampsia

A

BP >140/90
2 BP readings 4-6 hours apart
Proteinuria >300mg/24 hours urine or >+1 on dipstick on 2 specimens ( on 2 samples 4-6 hours apart)
occurs after 20 weeks gestation
may see: elevated reflexes
elevated hemoglobin d/t hemoconcentration
mild edema

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11
Q

severe preeclampsia

A
BP >160/110mmHG
on 2 BP readings 4-6 hours apart 
proteinuria >5g/24 hours urine or >+3 on dipstick (on 2 samples 4-6 hours apart) 
occurs after 20 weeks gestation 
may see: epigastric pain 
visual disturbances 
headaches
clonus
dim. renal function ( increase BIN; serum creatinine >1.2mg/dL; decreased creatinine clearance)
thrombocytopenia 
oliguria
edema
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12
Q

Eclampsia

A

Grand mal seizures that cannot be attributed to other causes in a woman with preeclampsia
occurs in 0.1% of women with preeclampsia
cause: fetal distress, abruption, death

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13
Q

chronic HTN

A

REFERRAL

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14
Q

Chronic HTN increased risk for

A
FGR
preterm birth 
preeclampsia 
placental abruption 
pulmonary edema 
renal failure 
perinatal mortality 3-4 times greater.
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15
Q

chronic HTN superimposed w/ preeclampsia

A

dx HTN prior to 20 weeks gestation and new onset proteinuria >300mg/24 hour after 20 weeks gestation
thrombocytopenia after 20 weeks gestation
worsening of HTN as pregnancy progresses

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16
Q

Preeclampsia etiology

A

abnormal placentation
inflammatory changes provoke endothelial cell injury
mild-severe microangiopathy of target organs such as brain liver kidney placenta
extreme case lead to liver failure, renal failure DIC CNS abnormalities
giving birth is only cure

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17
Q

preeclampsia risk factors

A
nulliparity
multifetal gestation 
age extremes 35 
African American race 
DM 
prior hx preeclampsia
family hx of HTN or preeclampsi
obesity 
limited exposure to partner sperm (new partner --immunologic factors involved) 

smoking does not increase risk for preeclampsia

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18
Q

Data gathering

objective:

A

(1) BP
(2) urine for protein
if 2 positive then :
check for risk factors
weight gain pattern
edema
DTR
epigastric tenderness/liver margins
opthalmic exam fo papilledema

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19
Q

Data gathering

subjective:

A

Headaches ?
dizziness ?
blurry vision
epigastric pain

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20
Q

Best position to take BP

A

after rest
UPRIGHT
NO tobacco or caffeine within 30 minutes of measurement.

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21
Q

LABS for preeclampsia

A

CBC incl. platelets
24 hour urine or albumin to creatinine ratio
liver enzymes (AST, LDH, ALT)
renal function tests (Creatinine clearance, serum uric acid, BUN, serum creatinine)
COAGULATION studies (PTT, fibrinogen, PTPT) if low platelets)

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22
Q

how often do labs done if stable

23
Q

proteinuria (preeclampsia)

24
Q

urine dipstick (preeclampsia)

25
protein/creatinine ratio (preeclampsia)
>0.3
26
serum uric acid (preeclampsia)
>5.6 mg/dL
27
serum creatinine (preeclampsia)
>1.2 mg/dL
28
Platelets
<100,000/ mm
29
PT or aPTT
ELEVATED
30
fibrinogen
DECREASED
31
d-Dimer
INCREASED
32
Hemolysis
abnormal peripheral smear indirect bilirubin >1.2mg/dL lactate dehydrogenase >600U/L
33
elevated liver enzymes
AST > 70 u/L
34
preeclampsia (Blood)
hematocrit increased (hemoconcentration) platelet count <100,000 **lower platelet higher the maternal fetal morbidity**
35
preeclampsia (liver)
damage d/t subcapsular hemorrhage function tests increase in severe disease LDH, ALT, AST
36
renal damage
increased serum creatinine , uric acid, and protein urine | decreased creatinine clearance.
37
management : mild preeclampsia
obtain initial labs & consult can use expectant management co-manage with consultant if symptoms progress, collaborate care or refer
38
management : severe preeclampsia
immediately referral high proteinuria even w/ mild BP elevation (atypical presenation of preeclampsia rare but may be present and may be quite severe)
39
USN (surveillance)
q4 weeks if early preeclampsia
40
NST (surveillance)
1-2 x's per week
41
BPP
2x per week | office evaluation twice weekly for BP urine protein symptom evaluation fetal evaluation
42
preeclampsia labs (how often)
WEEKLY
43
at home management
hospitalize for initial /new onset of preeclampsia increased daily rest on left side adequate diet 3x per week urine protein and weight DAILY BP DAILY FMC office visit 2 times per weeks, every 3-4 days women with mild preeclampsia close to term have outcome similar to normo-tensive women
44
warning signs
``` persistent headaches visual disturbances epigastric pain general malaise oliguria sudden wt. gain or facial edema ```
45
when is induction indicated
mild preeclampsia at term with favorable cervix | worsening preeclampsia
46
MgSO4 indicated
in severe preeclampsia to prevent seizures | 4-6gm bolus followed by 1-2 gms/hr.
47
preeclampsia dx prior 36 weeks is risk for
preterm birth
48
Eclampsia prevalences & signs
``` before birth (38-53%) during labor (18-36%) after birth (11-44% most within 48 hours PP) signs: HA, visual changes, epigastric pain, restlessness. ```
49
actions during seizures
``` call out for help side rails up & pad on sides turn on side to prevent aspiration insert padded tongue blade clear airway Administer oxygen IV access for MgSO4 ASsess fetal status after seizure over ```
50
HELLP syndrome common presentation
``` gen. malaise "flu" epigastric & RUQ pain N/V HTN (severe mild or absent) proteinuria - significant or absent. ```
51
HELLP syndrome 3 classic lab abnormalities
elevated liver enzymes low platelet count ***best indicator** anemia -- last to appear
52
dx preeclampsia
``` SBP 140 or DBP 90 (4 hours apart) SBP >160 or DBP 105 (90-60 minutes) & Proteinuria >300mg/24 hour Pro: Cr ratio >0.3mg dipstick 1+ OR new onset of : cerebral/vision symptoms, pulmonary edema, platelet count 1.2mg/dL , elevated liver enzym (>2x normal), LDH >600IU/L hemoconcentration ```
53
coagulation studies in preeclampsia
PT : elevated INR :elevated PTT: elevated fibrinolgen : LOW