NM Quizzes

Question 1

What type of cells creat myelin in the peripheral NS?

Answer 1

schwann

Question 2

whay type of cells creat myeline in the CNS?

Answer 2

oligodendrocytes

Question 3

What is the conduction velocity off nerves with very thick coats of myelin

Answer 3

very fast

Question 4

Which of the following conditions involve the mmotor end plate of a nerve?

diabetic neuropathy

myasthenia gravis

postpolio

Answer 4

myasthenia gravis

Question 5

Which disease is the most physically devastating of the neurodegenerative diseases>?

Answer 5

ALS

Question 6

Which of the following is best describes as the study of how biologic and environmental signals determine gene expression?

genetics

epigentics

genomics

Answer 6

epigenetics

Question 7

A person’s genetic makeup account for what percent of obesity?

Answer 7

40-70%

Question 8

What kind of impairments occur for those affected with acute poliomyelitis?

Answer 8

focal and asymmetric motor impairments

Question 9

For those affected with postpolio syndrom, recovery is attributed to reinnervation of the denervatedmuscle fibers by what…?

Answer 9

collateral sprouting

Question 10

What neuropathy is classified as a metabolic neuropathy?

Answer 10

diabetic neuropathy?

Question 11

What is the immune mediated inflammatory neuropathy?

Answer 11

guillain barre

Question 12

What is the autoimmune myopathy?

Answer 12

myasthenia gravis

Question 13

What are the hereditary myopathies?

Answer 13

limb girdle dystrophy

facioscapular dstrophy

duchenne’s dystrophy/becker dystropy

Question 14

What is a hereditary neuropathy?

Answer 14

charcot-marie-tooth

Question 15

What disease has upper and lower motor neuuro features?

Answer 15

ALS

Question 16

Which type of muscular dystrophy becomes most apparent between 2-5 years of age

Answer 16

Duchennes MD

Question 17

What age do children with DMD lose the ability to walk

Answer 17

10-12 years of age

Question 18

Which NM disease is characterized by progressive weakness and wasting of skeletal muscles resulting from anterior horn cell degneration?

CMT

DMD

SMA

Answer 18

Spinal muscular atrophy (SMA)

Question 19

Which NM disorder do individuals have a higher incidence of learning disorders, autism like features and lower than average IQ?

Answer 19

duchenne MD

Question 20

Charcot Marie Tooth NM disease results in what type of deficits>

Answer 20

primary motor and sensory deficits

Question 21

Which NM disease is a loud foot slapping, steppage gait patttern very common?

SMA

CMT

DMD

Answer 21

charcot marie tooth

Question 22

Duchenne MD hallmark signs include..

Answer 22

psuedohypertrophy

Gower’s sign

proximal weakness

Question 23

What is calf pseudohypertrophy?

Answer 23

as muscle degenerates, the calf muscles are infiltrated with fatty and fibrous tissue

Question 24

What gene is the largest in the body?

Answer 24

dystrophin

Question 25

Which of the following therapies are not used to treat SMA Nusinersen Risdiplam corticosteriods

Answer 25

corticosteroids

Question 26

What scale best dscribes the cogntive behavioral stages oof decline in AD?

Answer 26

global deterioration scale

Question 27

Which medication may be used to treat dementia ?

Answer 27

medications that block ACh breakdown

Question 28

What are the subcortical dementia's?

Answer 28

Lewy Body dementia Huntington's disease

Question 29

What are the cortical types of dementia's?

Answer 29

Alzheimer's vascular dementia frontotemporal dementation Wernicke-Korsakoff's syndrome pugilistic dementia (CTE)

Question 30

What is the most beneficial regarding exercise programs for individuals regardless of dementia stage?

Answer 30

mobility training and physical activity

Question 31

True or False Individuals with dementia must be able to explicitly remember all of their exercises in order to demonstrate benefit from them on standardized measures such as Berg Balance Scale, Timed Up and Go and gait speed tests.

Answer 31

False

Question 32

A group of cognitive disorders characterized by memory impairment, difficulty with language, motor ability, object recognition and executive function is describes what?

Answer 32

dementia

Question 33

True or False Chronic Traumatic Encephalopathy (CTE) is associated with repeated hits to the head causing multiple concussions and can only be diagnosed definitively through post-mortem brain tissue analysis.

Answer 33

True

Question 34

what is the 2nd most common type of dementia

Answer 34

vascular dementia

Question 35

What type of dementia is characterized by neurofibrilary tangles and neuritic plaquues with amyloids

Answer 35

Alzheimer's dementia

Question 36

What dementia is caused by EtOH abuse

Answer 36

Wernicke's Korsakoff's syndrome

Question 37

Ture or False Research in Mild Cognitive Impairment (MCI) and Alzheimer's Dementia suggests a clear link between declining cognition in these disorders with declining balance ability.

Answer 37

TRUE

Question 38

Which of Teepa Snow's "GEMS Brain Change Model" analogies describes an individual at the late or end stages of dementia?

Answer 38

Pearl

Question 39

Where in the brain is the initial source of pathology located in PD?

Answer 39

substantia nigra

Question 40

The diagnosis of PD is most typically made by clinical findings of the cardinal signs of PD and a positive response to...

Answer 40

dopamine replacement

Question 41

What are the cardinal signs of PD

Answer 41

tremor, rigidity, postural instability, and bradykinesia

Question 42

Progressive Supranuclear Palsy (PSP) is characterized by what?

Answer 42

the inabilit to look down and sever postural instability

Question 43

The progression of what is faster than the tremor form of PD

Answer 43

postural instability and gait disoders (PIGD)

Question 44

Individuals in the later stages of PD typically have an excessive forward flexed posture including increased forward head position, thoracic kyphosis, hip flexion, elbow flexion and knee flexion. This posture creates a shift of the center of mass forward which can contribute to which of the following? balance difficulties and increased fall risk festinating gait increased risk for MSk impairment all the above

Answer 44

balance difficulties and increased fall risk festinating gait increased risk for MSk impairment

Question 45

What is the most common non motor sign of PD?

Answer 45

olfactory loss, cognitive impairment, dperession

Question 46

Which oHoehn and Yahr stages of PD are described as unilateral symptoms only?

Answer 46

Stage 1

Question 47

Whcih H&Y stage of PD are described as bilateral symptoms with postural instability (unable to recover on the posterior pull test)?

Answer 47

H&Y Stage 3

Question 48

What are primary categories of PT intervention for people with PD

Answer 48

aerobic condition task specific training flexibility strengthening

Question 49

Extended Disability Status Scale (EDSS) scores best describes an individual who has severe disability with restriction to bed or wheelchair?

Answer 49

EDSS 8.0

Question 50

What are common barriers to exercise for individuals with MS

Answer 50

Heat senstivity, fatigue, pain

Question 51

What areas of the nervous system does MS affect?

Answer 51

the brain and spinal cord

Question 52

Extended Disability Status Scale (EDSS) scores best describes an individual who has mild disability overall, with slightly greater disability in one functional system?

Answer 52

EDSS 2.0

Question 53

Between what ages are females most commonly affected by MS?

Answer 53

ages 20-50

Question 54

Multiple Sclerosis is a chronic neurodegenerative disorder of the CNS which is characterized by demyelination by an autoimmune process. Which cells are responsible for myelin production in the CNS?

Answer 54

oligodendrocytes

Question 55

What are the most common initial presentations of MS

Answer 55

optic neuritis, sensory changes, weakness

Question 56

The McDonald Criteria for diagnosing Multiple Sclerosis is best described by which of the below? MRI lesions in 2 of 4 areas (dissemination in space) and a relapse and/or new lesions on MRI (dissemination in time) Cerebrospinal fluid analysis only Clinical diagnosis only; MRI findings don't contribute

Answer 56

MRI lesions in 2 of 4 areas (dissemination in space) and a relapse and/or new lesions on MRI (dissemination in time)

Question 57

True or False There are disease-modifying drugs for Multiple Sclerosis that significantly decrease new lesion development, progression of the disease and relapse rates.

Answer 57

TRUE