NMJ

Question 1

Presynaptic neuron

Answer 1

Aa motor neuron, p/q calcium channels, ACh and vesicles

Question 2

Motor end plate

Answer 2

nmAChR, EPP, MAP

Question 3

Pathway

Answer 3

Action potential in the neuron, activates the p/q calcium channel and lets calcium in, vesicles transport ACh, ACh binds to the nmAChR, depolarization triggers an end plate potential, VG sodium channel is activated, MAP occurs

Question 4

Infant Botulism

Answer 4

Lowered ACh, lowered EPP and MAP, decreased muscle tone, difficulty breathing, delayed gross motor skills. Floppy baby syndrome

Question 5

Myasthenia gravis

Answer 5

Destroys nmAChR, cranial muscle problems, swallowing problems, breathing problems, AChE inhibitor to treat (depolarization blockade)