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MSK II Exam I > NMJ Drugs > Flashcards

NMJ Drugs Flashcards

(31 cards)

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1
Q

Atracurium

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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2
Q

Cisatracurium

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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3
Q

Doxacurium

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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4
Q

Metocurine

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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5
Q

Mivacurium

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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6
Q

Tubocurarine

A

Nondepolarizing NMJ blocker- Isoquinoline derivative

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7
Q

Pancuronium

A

Nondepolarizing NMJ blocker- steroid derivative

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8
Q

Pipecuronium

A

Nondepolarizing NMJ blocker- steroid derivative

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9
Q

Rocuronium

A

Nondepolarizing NMJ blocker- steroid derivative

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10
Q

Vecuronium

A

Nondepolarizing NMJ blocker- steroid derivative

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11
Q

Succinylcholine

A

Depolarizing NMJ blocker
AE: hyperkalemia, increased intraoccular pressure
CI: malignant hyperthermia, not with kids <12 (cardiac arrest risk if underlying skeletal muscle myopathy)

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12
Q

Dantrolene

A

Muscle relaxant(spasmolytic) - inhibits ryanodine receptors(malignant hyperthermia)

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13
Q

Botulinum toxin

A

Muscle relaxant(spasmolytic) - cleaves SNARE complex

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14
Q

Ambenonium

A

AChE inhibitor

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15
Q

Donepezile

A

AChE inhibitor

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16
Q

Echothiophate*

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A

AChE inhibitor

17
Q

Edrophonium*

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A

AChE inhibitor

18
Q

Galantamine

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A

AChE inhibitor

19
Q

Neostigmine*

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A

AChE inhibitor

20
Q

Physostigmine*

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A

AChE inhibitor

21
Q

Pyridostigmine*

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A

AChE inhibitor

22
Q

Rivastigmine

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A

AChE inhibitor

23
Q

Tacrine

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A

AChE inhibitor

24
Q

Atropine*

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A

Antimuscarinic compunds

25
nondepolarizing NM blocking agents
distribute fast, eliminate slow poor solubility competitive antagonists at nAChR
26
how to reverse nondepolarizing NM blocking agents
add acetylcholine or succinylcholine or cholinesterase inhibitors neostigmine/pyridostigmine - AChE inhibitors that increse release
27
What do you give with AChE inhibitors?
Anticholinergic agents - atropine glycopyrrolate | prevent bradycardia, bronchoconstriction
28
AE of nondepolarizing NM blocking agents
can cause histamine release - wheals, bronchospasm, hypotension, bronchial/salivary secretion -less with steroids CV effects of hypotension and tachycardia
29
What drugs use for rapid sequence intubation
succynilcholine, rocuronium, vecuronium
30
What drugs for surgical muscle relaxation
pancuronium, atracurium, cisatracurium
31
Drugs for hepatic/renal insufficiency?
atracurium, cisatracurium

MSK II Exam I (5 decks)

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