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PHRM844 > Non-Insulin Therapy > Flashcards

Non-Insulin Therapy Flashcards

1
Q

metformin brand names

A

-Glucophage
-Fortamet
-Glumetza

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2
Q

SGLT2 inhibitors

A

-canagliflozin
-dapagliflozin
-empagliflozin

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3
Q

canagliflozin brand name

A

Invokana

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4
Q

dapagliflozin brand name

A

Farxiga

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5
Q

empagliflozin brand name

A

Jardiance

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6
Q

canagliflozin dose for eGFR > 60

A

-100 mg PO QD
-max: 300 mg PO QD

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7
Q

canagliflozin dose for eGFR 30-60

A

-max: 100 mg PO QD if no albuminuria

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8
Q

canagliflozin dose for eGFR < 30

A

-do not start canagliflozin
-if already taking, may take 100 mg PO QD if albuminuria > 300 mg/day

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9
Q

dapagliflozin dose for eGFR > 45

A

-5 mg PO QD
-max: 10 mg PO QD

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10
Q

dapagliflozin dose for eGFR < 25

A

-do not start dapagliflozin
-if already taking, may continue and monitor

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11
Q

empagliflozin dose for eGFR > 30

A

-10 mg PO QD
-max: 25 mg PO QD

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12
Q

empagliflozin dose for eGFR < 30

A

-do not start empagliflozin
-if already taking, may continue and monitor

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13
Q

ertugliflozin dose for eGFR > 60

A

-5 mg PO QD
-max: 15 mg PO QD

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14
Q

ertugliflozin dose for eGFR < 45

A

-do not start ertugliflozin
-if already taking and eGFR is low, then discontinue

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15
Q

GLP-1 agonists

A

-liraglutide
-dulaglutide
-semaglutide

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16
Q

liraglutide brand name

A

Victoza

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17
Q

dulaglutide brand name

A

Trulicity

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18
Q

semaglutide brand names

A

-Ozempic
-Rybelsus

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19
Q

dulaglutide dosing

A

-0.75 mg SQ QW up to 4.5 mg SQ QW
-use with caution in pts with ESRD

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20
Q

dulaglutide needles?

A

attached to pens

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21
Q

semaglutide dosing

A

-0.25 mg SQ QW for 4 weeks, then 0.5 mg SQ QW up to 2 mg SQ QW

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22
Q

semaglutide needles?

A

in pen carton

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23
Q

liraglutide dosing

A

-0.6 mg SQ QD for 7 days, then 1.2 mg SQ QD up to 1.8 mg SQ QD

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24
Q

liraglutide needles?

A

not included

25
Q

Byetta dosing

A

-5 mcg SQ BID for 1 month, then 10 mcg SQ BID
-avoid in pts with CrCl < 30 mL/min

26
Q

Byetta needles?

A

not included

27
Q

Bydureon Bcise dosing

A

-2 mg SQ QW
-avoid in pts with CrCl < 30 mL/min

28
Q

Bydureon Bcise needles?

A

included

29
Q

lixisenatide dosing

A

-10 mcg SQ QD for 14 days, then 20 mcg SQ QD
-avoid in pts with eGFR < 15

30
Q

lixisenatide needles?

A

not included

31
Q

dual GLP-1 agonist and GIP

A

tirzepatide

32
Q

tirzepatide brand name

A

Mounjaro

33
Q

DPP-4 inhibitors

A

-sitagliptin
-saxagliptin
-linagliptin
-alogliptin

34
Q

sitagliptin brand name

A

Januvia

35
Q

saxagliptin brand name

A

Onglyza

36
Q

linagliptin brand name

A

Tradjenta

37
Q

alogliptin brand name

A

Nesina

38
Q

sitagliptin dose for CrCl > 50 mL/min

A

100 mg PO QD

39
Q

sitagliptin dose for CrCl 30-50 mL/min

A

50 mg PO QD

40
Q

sitagliptin dose for CrCl < 30 mL/min or patients with ESRD on HD

A

25 mg PO QD

41
Q

saxagliptin dose for CrCl > 50 mL/min

A

2.5 mg - 5 mg PO QD

42
Q

saxagliptin dose for CrCl < 50 mL/min

A

2.5 mg PO QD

43
Q

linagliptin dose

A

5 mg PO QD (not excreted by kidneys, so no dosage adjustment required)

44
Q

alogliptin dose for CrCl > 60 mL/min

A

25 mg PO QD

45
Q

alogliptin dose for CrCl 30-60 mL/min

A

12.5 mg PO QD

46
Q

alogliptin dose for CrCl < 30 mL/min or patients with ESRD on HD

A

6.25 mg PO QD

47
Q

sulfonylureas

A

-glyburide
-glipizide

48
Q

glyburide brand names

A

-Diabeta
-Micronase
-Glynase

49
Q

glipizide brand names

A

-Glucotrol
-Glucotrol XL

50
Q

Glucotrol starting dose

A

2.5 mg - 5 mg PO QD

51
Q

Glucotrol max dose

A

40 mg (but stop at 20 mg if not seeing much BG benefit)

52
Q

Glucotrol XL starting dose

A

2.5 mg - 5 mg PO QD

53
Q

Glucotrol XL max dose

A

20 mg PO QD

54
Q

Micronase/Diabeta starting dose

A

1.25 mg - 5 mg PO QD

55
Q

Micronase/Diabeta max dose

A

20 mg PO QD

56
Q

Glynase starting dose

A

1.5 mg - 3 mg PO QD

57
Q

Glynase max dose

A

12 mg PO QD

58
Q

thiazolidinedione

A

pioglitazone

59
Q

pioglitazone brand name

A

Actos

PHRM844 (4 decks)

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