NORA Flashcards
(62 cards)
Define MAC
Greater than MODERATE depth
Requires same preop and intraop care
Patient must retain consciousness and the ability to respond purposefully-not what actually happens
ALWAYadministered by anesthesia provider
Main differences between 4 levels of sedation
Minimal
Moderate- no airway intervention
Deep- airway intervention may be required
General-intervention often required
Expectations during MAC
Psychological support
And everything else that is required during general
Good MAC candidates
Can remain motionless
Can follow directions
Can tolerate conversion to general
MAC main complication
Respiratory compromise from excessive sedation
NOT less risky than generak
Risk of MAC vs General
MAC is not less risky than GA in terms of permanent brain injury or death
Problems with MAC med titration
There is significant variability in individuals response to medications- we are all snowflakes
Goal is consistent plasma concentrations and avoiding oversedation/airway compromise
Elimination half-life
Time necessary for the plasma concentration of a drug to be reduced by half
Context sensitive halftime
Time for plasma concentration of a medication to be reduced by half after cessation of an infusion of a certain duration
Half time equilibration constant?
Used to assess the time to effect after a bolus and removal of drug from effect site after cessation of infusion
A drug with short t1/2 Keo will demonstrate what?
Keo=equilibrium constant
Rapid equilibrium between plasma and brain and will have a shorter delay in onset
CPss50
Plasma concentration required to abolish purposeful movement at skin incision
Two qualities we love about propofol
Amnestic and hypnotic
Ketamine considerations in MAC
Minimal resp and card depression
Hallucinations
Oral secretions can cause laryngospasm-glyco
Good adjunct for propofol but only use low dose in outpatient setting
Dexmedetomidine
Central presynaptic alpha-2 agonist
Increases vagal tone=hypotension and bradycardia
Slow onset-sticks around
Potentiates analgesia of opioids
Why are MAC patients at risk of airway fire? -
Uncontrolled airway and an open oxygen source
What is the fire triad?
Ignition source
Fuel source- alcohol prep
Combustible gas- O2
What are our flammable gasses?
Oxygen and Nitrous
NOT the halogenated anesthetics
Preventing OR fires
Flushing under the drapes with AIR
Use air/oxygen blender
Keep drapes off patients face
Use harmonic scalpel or bipolarelectrosugery NOT cautery
First thing in airway fire?
Turn off O2
2nd and 3rd step in airway fire
Pull out burning material
Replace ETT
What can increase chances of LAST?
Cardiovascular depression= reduced hepatic flow and buildup of local
What potentiates cardiovascular toxicity of LAST?
Hypercarbia
Acidosis
Hypoxia
Signs of last
Sedation
Numbness of the tongue/circumoral tissues
Metallic taste
Restlessness, vertigo, tinnitis, inability to focus
Slurred speech, skeletal muscle twitching
Tonic-clonic seizures
Cardiovascular toxicity