Norepinephrine Flashcards
1
Q
Norepinephrine (names)
A
Noradrenaline, Levophed
2
Q
NE Drug Class
A
direct acting adrenergic agonist; therapeutic class - vasopressor, vasoconstrictor
3
Q
NE Pharmadynamics
A
MAJOR: stimulate peripheral alpha 1 adrenoceptors -> vasoconstriction (resistance arterioles, increase SVR) venoconstriction ( in capacitance vessels, INCREASE PRELOAD).
Inc. CO, SVR, MAP, decrease blood flow to skin, muscle, kidney.
Also stimulates beta1 receptors in the heart, inc. HR and contractility
MAIN: vasoconstriction and cardiac stimulation
