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SBM Haeme > Normal Lymphogenesis > Flashcards

Normal Lymphogenesis Flashcards

1
Q

B-specific markers

A

CD-19/79

CD-10/20/22

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2
Q

B sx?

A

fever, night sweats, weight loss

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3
Q

determining clonality

A

B-cell: K:L ratio (nl 2:1)

T-cell: PCR the TCR

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4
Q

t(14;18)?

A

bcl2—> follicular (B-cell) lymphoma (an NHL)

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5
Q

t(11;14)?

A

mantle cell lymphoma

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6
Q

t(8;14)

A

Burkitt’s

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7
Q

follicular B cell lymphoma CDs

A

19+ 20+ 10+ 5-

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8
Q

small B-cell

A

light chain, CD 19+ 20+ 10- (vs follic) 23+

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9
Q

classifying lymphomas

A

NHL
—B-cell (precursor) (mature)
—NK/T cell (precursor ) (mature)

Hodgkin’s

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SBM Haeme (14 decks)

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