Normal microbiota Flashcards
(24 cards)
what is Microbiology?
science of microscopic life forms (microorganisms or life forms)
-ubiquitous - virtually everywhere
what is an infectious disease?
- disease caused by invasion of a pathogen that grows and multiplies- not all microbes are disease producing
- only 3 percent are pathogenic (cause disease)
History of Microbiology
- anton van leeuwenhoek
- Louis Pasteur
- alexander emile jean yersin
- Robert Kock
- alexander fleming
- edward jenner
- rudolf virchow
- father of microbiology and created first microscope he did not link his “animalcules to disease
- discovered life forms that can exist without water and discovered that microorganisms cause disease and developed vaccines for rabies
- discovered causative agent for plague
- discovered germ theory-discovered tb, v. cholera, b anthacis is truly causative of anthrax and developed Kochs postulates
- discovered penicillin
- discovered small pox vaccine
- discovered biogenisis
what is kochs postulate?
to prove that a specific microorganism is the cause of a specific infectious disease
what is the importance of microbiology to dental hygiene practice?
- protection for ourselves and for our clients against disease
- learning about disease so we are aware of symptoms
- inform client about diseases
- prevent spread of infectious disease
- terminology to collaborate with other healthcare proffessionals
order of mircrobial classifications
hint: king david came over for good spaghetti
kingdom, division, class, order, family, genus, species
ie) humans: Animalia, chordata, mammalia, primates, hominidae homo homo sapien
what is normal micriobiota? and what is its importance?
mixed population of aerobic and anerobic microorganisms living on us
-it stimulates immune system, colonization resistance, excrete products that inhbit foreign microbes, aid in digestion
define colonisation
entrance of infectious agent into a human and its growth and multiplication within the human (not causing disease) ex) staphylococcus aureus
define infection
colonisation has occurred and resulted in infection
define infectious agent
any living organisms that can cause infection and can be spread from one susceptible human to another
define communicable disease
a disease whose infectious agent is capable of being transmitted from one person to another ie)influenza or HIV
define incubation period
time between the entrance of an infectious agent into a patient and the development of actual illness
define pathogenicity
ability of an infectious agent to cause a disease
define virulence
-things that make microorganisms more virulent?
refers to the degree of pathogenicity
-flagella, incapsulation
define culture
to grow microorganisms from patient specimens or a growth of mirco-organisms
define opportunistic pathogen
any member of human or environmental microbiota that is normally harmless but cause infection when the body defenses are abnormal
why do different parts of the body inhabited normally by microbes and others are sterile?
the body parts that are highly inhbited are mouth, colon (largest amount), resp tract, gastrointestinal tract
-things that are sterile: fetus, lymph
what do microbiota need to grow?
nutrients, water, warmth, neutral ph,
uses of microbiota outside of the humans
- food industry
- digestion
- bioremediation (oil spills)
- water treatment
- chemical production
- drug production
- biological warfare
the four forms of infection
- pyogenic (puss producing)
- granulomatous infection (immunodeficiency disease of bacterial or fungal
- toxigenic infection (infection produced by toxins)
- intracelluar infection (bacteria that lives in human cells)
strep throat
- what form of infection is it?
- caused by?
- does bacteria have capsule?
- mechanism?
- pyogenic
- bacteria- streptococcal pharyngitis
- yes– harder to kill of
- throat sore, exotoxin, beefy red throat
tuberculosis
- what form of infection (disease mechanism)?
- transmission
- is bacteria resistant?
- granulomatous infection–bacteria takes a long time to show symptoms
- aerosolized droplet or airborne
- yes- resistant macrophages
tetanus
- what form of infection(disease mechanism)?
- what is the infectious agent?
- is the bacteria resistant?
- toxigenic infection–>neurotoxin that inhbits central ns and causes muscle spasms
- clostridium tetani (bacteria)
- bacteria has a spore–>withstand heat and many other things
Influenza
what form of infection is it?
infectious agent?
what is the disease mechanism?
- intracellular infection
- virus– influenza virus a,b and c
- mechanism- causes fever, cough, muscle pain