NS4004

Question 1

WHO definition of maternal death

Answer 1

Death of woman whilst pregnant or within 42 days of termination from any cause related or aggravated by pregnancy

Question 2

Classification of maternal deaths?

Answer 2

Direct- primary PPH, ectopic, hypertensive disorder
Indirect- pre-existing conditions, embolism
Incidental- car accident

Question 3

Fetal death/stillborn

Answer 3

No signs respiration/heart beat at 20weeks or more or over 400g

Question 4

Neonatal death definition

Answer 4

Death occurring within 28 days of life

Question 5

Perinatal death

Answer 5

fetal/stillbirths of at least 20w or 400g

Question 6

What is the other name for anterior/posterior pituitary and what hormones do they release?

Answer 6

Neurohypophysis- posterior: Oxytocin, ADH

Adenohypophysis- anterior: all others

Question 7

Where is HCG released and what is its function?

Answer 7

Produced and released from gonatropic cells of placenta. Function: maintenance of corpus lute, inhibits foreign body response on placental cells from mother, induces vomiting

Question 8

Oestrogen production and function

Answer 8

Production: ovaries and then placenta
Function: Uterine growth, vaginal lubrication, fat deposition, decrease gut motility

Question 9

Oxytocin production and function?

Answer 9

Production: Posterior pituitary
Function: Cervical ripening, uterine contractions

Question 10

Progesterone production and function

Answer 10

Production: ovaries, corpus luteum, adrenal glands
Function: Increased endometrial lining, breast development

Question 11

Relaxin production and function

Answer 11

Production: ovaries, placenta
Function: relaxation pelvis, inhibits contractions in pregnancy

Question 12

HPL production and function

Answer 12

Production: placenta
Function: decrease maternal insulin sensitivity, decrease glucose utilisation, increased lipolysis

Question 13

FSH production and function

Answer 13

Production: anterior pituitary
Function: Follicular growth

Question 14

TSH production and function

Answer 14

Production: Produced pituitary and released from thyroid gland
Function: metabolic rate

Question 15

Cortisol production and function

Answer 15

Production: adrenal cortex
Function: stress hormone, increase BSL, control body temp, reduce inflammation

Question 16

Prolactin production and function

Answer 16

Production: anterior pituitary
Function: response milk production, enlargement mammary glands

Question 17

HCG effect on pregnancy

Answer 17

Increased HCG associated with hyperemesis, molar pregnancy. HCG stimulated thyroid gland potentially causing hyperthyroidism

Question 18

Oestrogen effect on pregnancy

Answer 18

Increased- Adenomyosis, uterine fibroids, osteoporosis

Question 19

Oxytocin effect on pregnancy

Answer 19

Contractions

Question 20

Progesterone effect on pregnancy

Answer 20

Asthma- improves, excess associated with congenital adrenal hyperplasia, lack of progesterone- miscarriage

Question 21

Relaxin effect on pregnancy

Answer 21

Decreased tissue fibrosis- PCOS, SLE

Question 22

HPL effect on pregnancy

Answer 22

Insulin resistance- GDM

Question 23

TSH effect on pregnancy

Answer 23

Increased associated molar pregnancy or hyperemesis. Congenital hypothyroidism.

Question 24

Prolactin effect on pregnancy

Answer 24

Excess associated with hypothyroidism or pituitary tumour