nucleic acids Flashcards

1
Q

why are nucleic acids important

A

they are information carrying molecules

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2
Q

what nuclei acids polymers of

A

nucleotides

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3
Q

whats the structure of a nucleotide

A

-phosphate group
-pentose
-nitrogen containing base

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4
Q

what are the components of an RNA nucleotide

A

-phosphate group
-ribose
-one of the organic bases (including uracil)

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5
Q

what do nucleotides join together to form

A

phosphodiester bonds by condensation reactions

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6
Q

where is the phosphodiester bond formed

A

between the phosphate group which is attached to the 5’ carbon on the pentose of the 1st nucleotide and the 3’ carbon on the pentose of the 2nd nucleotide

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7
Q

functions of nucleic acids

A

-DNA holds and stores genetic info and RNA transports the genetic info from DNA to ribosomes
-ribosomes themselves are made from RNA and protein

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8
Q

structure of nucleic acids

A

-DNA molecule consist of 2 polynucleotide chains held together by hydrogen bonds between specific complimentary base pairs
thymine to adenine (2 bonds)
cytosine to guanine (3 bonds)
-2 stands are twisted into a double helix

RNA molecule is formed of a single polynucleotide chain which is usually short in comparison to a DNA molecule

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9
Q

what does ATP stand for

A

adenine triphosphate

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10
Q

what is ATP formed with

A

from a molecule of ribose, molecule of adenine and 3 phosphate groups

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11
Q

what does ATP hydrolase do

A

hydrolyses the ATP and removes the last phosphate group to produce inorganic phosphate and ADP
adenine diphosphate

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12
Q

what type of reaction is ATP

A

exothermic reaction
releases the right amount of energy to be used in a single step of a biochemical process

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13
Q

what happens to the phosphate that is released in the hydrolysis of ATP

A

may be added to another compound (eg when glucose is phosphorylated it makes it more reactive so it can take part in endo thermic reaction)

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14
Q

steps of phosphate being added to glucose

A
  1. glucose + ATP = glucose-1-phosphate
  2. glucose-1-phosphate + glucose = pi + water + maltose
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15
Q

structure and function of DNA

A

-complimentary base pairs- code for genetic info
-helical structure (double)- preserves info - strong sugar phosphate backbone protects base pairs
-base pairs are joined by hydrogen bonds- weak, easily broken for replication, however many hydrogen bonds between base pairs join strands together securely giving stability
double stranded- therefore both strands can be copied in semi-conservation replication
-very long- can hold a lot of info

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16
Q

structure and function of RNA

A

-short- can carry info for 1 or a few genes
-single stranded- bases are exposed on mRNA and combine with tRNA or it can fold and form base pairs with itself in tRNA and rRNA
-less stable than DNA- so mRNA can be broken down after it has been used