Nucleophilic Substitution

Question 1

SN1 rxn

Answer 1

Designation for an unimolecular nucleophilic substitution rxn
(only depends on 1 species, the substrate)

Question 2

Mechanism of SN1 rxn

Answer 2

1. Dissociation of a molecule into a carbocation and a good leaving group
2. combination of the carbocation w/ a nucleophile

Question 3

Summary of SN1

Answer 3

2 steps
favored in polar protic solvent
substrate: 3>2»1
rate: k[RX]

Question 4

SN2 rxn

Answer 4

Involves a strong nucleophile pushing its way into a compound while simultaneously displacing the leaving group

• The rate-limiting step has a molecularity of two
• An inversion of molecular geometry occurs

Question 5

Mechanism of SN2 rxn

Answer 5

1. actively displaces the leaving group in a backside attack

Question 6

Summary of SN2

Answer 6

1 step
favored in polar aprotic solvent
substrate: 1>2»3
rate: k[Nu][RX]